Neuroscience News and Research

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Triggering CD45 molecule blocks early development of AD

A new target for the prevention of adverse immune responses identified as factors in the development of Alzheimer's disease (AD) has been discovered by researchers at the University of South Florida's Department of Psychiatry and the Center of Excellence for Aging and Brain Repair.

27 Jan 2011

Researchers discover new sensory neurons that mediate BP and metabolism regulation in liver

For 60 years, scientists have puzzled over the possibility of a hepatic osmoreceptor that influences blood pressure regulation. Now, researchers of the Max Delbr-ck Center for Molecular Medicine Berlin-Buch, the Experimental and Clinical Research Center of the MDC and Charit- and the Hannover Medical School appear to have made a breakthrough discovery.

27 Jan 2011

Teen brains react with erratic excitement during reward-driven tasks

University of Pittsburgh researchers have recorded neuron activity in adolescent rat brains that could reveal the biological root of the teenage propensity to consider rewards over consequences and explain why adolescents are more vulnerable to drug addiction, behavioral disorders, and other psychological ills.

27 Jan 2011

Abbott fourth quarter worldwide sales increase 13.4% to nearly $10 billion

Abbott today announced financial results for the fourth quarter ended Dec. 31, 2010.

27 Jan 2011

Inviragen completes memorandum of understanding with Duke-NUS

Inviragen, and the Duke-National University of Singapore Graduate Medical School announced today that they have completed a memorandum of understanding to establish a partnership between the two organizations.

27 Jan 2011

Potential therapy to enhance memory and prevent loss of long-term memory

Researchers from Mount Sinai School of Medicine have identified a therapy that may enhance memory and prevent the loss of long-term memory. The research is published in the January 27th issue of Nature.

27 Jan 2011

NINDS awards AndroScience $3.8M cooperative translational research grant for Kennedy's Disease

AndroScience Corp., based in San Diego, California, announced receiving a $3.8 Million, 3-year milestone-driven, cooperative translational research grant from the National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health (NIH).

25 Jan 2011

Eisai to seek marketing authorization for perampanel in the U.S. and EU

Eisai announced today that it will submit Marketing Authorization Applications in the United States and the European Union for the investigational compound perampanel (E2007) based on the results of three Phase III pivotal studies. Perampanel is a first-in-class, highly selective non-competitive AMPA-type glutamate receptor antagonist, discovered and being developed by Eisai for adjunctive treatment of partial onset seizures in patients with epilepsy.

25 Jan 2011

Glioblastoma's molecular flexibility helps resist nearly all treatment efforts

Glioblastoma, the most common and lethal form of brain cancer and the disease that killed Massachusetts Senator Ted Kennedy, resists nearly all treatment efforts, even when attacked simultaneously on several fronts. One explanation can be found in the tumor cells' unexpected flexibility, discovered researchers at the Salk Institute for Biological Studies.

25 Jan 2011

Eisai's eritoran ACCESS study in severe sepsis does not meet primary endpoint

Based on the preliminary findings from the ACCESS (A Controlled Comparison of Eritoran and Placebo in Patients with Severe Sepsis) trial, Eisai Inc. announced today that the company will not submit marketing authorization applications to regulatory authorities in the United States, the European Union and Japan by the end of the fiscal year (March 31, 2011), as previously planned.

25 Jan 2011

Researchers discover new treatment for difficult-to-control high blood pressure

Researchers were surprised to discover what may be a potential new treatment for difficult-to-control high blood pressure, according to a case report published in the January 25, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

25 Jan 2011

New research reveals dynamics behind signal transmission in brain

Surprising rate at which neuronal networks in the cerebral cortex delete sensory information. The dynamics behind signal transmission in the brain are extremely chaotic. This conclusion has been reached by scientists from the Max Planck Institute for Dynamics and Self-Organization at the University of Göttingen and the Bernstein Center for Computational Neuroscience Göttingen.

24 Jan 2011

Sleep on it to remember it better: Study

A new study says that the best way to remember something important is to remember it while you are asleep. The research, led by Bjorn Rasch of the University of Basel in Switzerland says that newly learned memories during sleep rather than when awake does a better job of strengthening the memory trace. This could help people with disorders such as post-traumatic stress disorder (PTSD) feel researchers.

24 Jan 2011

Perceived threat, rather than actual events, predict brain adaptation

A study of soldiers who took part in the ISAF mission in Afghanistan between 2008 and 2010 has found that their brains adapt when they are continuously exposed to stress. The perceived threat appears to be the major predictor of brain adaptation, rather than the actual events. In other words, if a roadside bomb goes off right in front of you, the degree to which you perceive this as threatening is what counts. This is what determines how the brain and the stress system adapt.

21 Jan 2011

Repligen enters exclusive license agreement with UCI for use of HDAC3 inhibitors for memory disorders

Repligen Corporation announced today that it has entered into an exclusive license agreement with the University of California, Irvine (UCI) for a patent application covering the use of histone deacetylase 3 (HDAC3) inhibitors for the treatment of disorders involving preservation or extinction of memory including Alzheimer's disease, memory impairment and post traumatic stress disorder.

21 Jan 2011

New research suggests humans use senses to keep track of time

Humans use their senses to help keep track of short intervals of time according to new research, which suggests that our perception of time is not maintained by an internal body clock alone.

21 Jan 2011

Anaesthetising an arm affects brain activity and rapidly impairs body perception

An Inserm research team in Toulouse, led by Dr Stein Silva (Inserm Unit 825 "Brain imaging and neurological handicaps"), working with the "Modelling tissue and nociceptive stress" Host Team (MATN IFR 150), were interested in studying the illusions described by many patients under regional anaesthetic.

20 Jan 2011

Study validates MultiStem as potential stem cell therapy for spinal cord injury

Case Western Reserve University School of Medicine and Athersys, Inc. announced a joint scientific study on spinal cord injury will be published today in the January issue of The Journal of Neuroscience.

20 Jan 2011

Takeda Cambridge, Evotec enter collaboration to identify novel modulators against GPCR

Evotec AG today announced that it has entered into a collaboration with Takeda Cambridge Limited, to identify small molecule modulators against GPCR and Protease targets involved in various CNS and Metabolic diseases.

20 Jan 2011

New research: HIV individuals are more likely to have stroke

New research suggests that people infected with human immunodeficiency virus may be up to three times more likely to have a stroke compared to those not affected with HIV. The study is published in the January 19, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

20 Jan 2011