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Esomeprazole is a proton pump inhibitor (brand names Sompraz, Zoleri, Nexium, Lucen, Esopral; Axagon in Italy, Nexiam in Belgium and South Africa) developed and marketed by AstraZeneca which is used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and Zollinger-Ellison syndrome. Esomeprazole is the ''S''-enantiomer of omeprazole (marketed as Losec/Prilosec), and AstraZeneca claims improved efficacy of this single enantiomer product over the racemic mixture of omeprazole. However, this greater efficacy has been disputed, with some claiming it offers no benefit from its older form.
Study links heartburn drugs to fatal cases of heart, kidney disease and gastrointestinal cancer

Study links heartburn drugs to fatal cases of heart, kidney disease and gastrointestinal cancer

Common acid reflux drugs tied to elevated risk for kidney disease

Common acid reflux drugs tied to elevated risk for kidney disease

Invasive surgery should be done for select patients with acid reflux, says study

Invasive surgery should be done for select patients with acid reflux, says study

Common acid reflux drugs linked to progression of chronic liver disease

Common acid reflux drugs linked to progression of chronic liver disease

Proton pump inhibitors linked to increased death risk

Proton pump inhibitors linked to increased death risk

Longtime use of heartburn drugs linked to increased risk of death

Longtime use of heartburn drugs linked to increased risk of death

Former pharma reps’ new mission: To school docs on high drug costs

Former pharma reps’ new mission: To school docs on high drug costs

Prolonged use of popular heartburn drugs linked to silent, gradual kidney damage

Prolonged use of popular heartburn drugs linked to silent, gradual kidney damage

Common heartburn medications could decrease effects of chemotherapy in cancer patients

Common heartburn medications could decrease effects of chemotherapy in cancer patients

Chronic use of antacid drugs may speed up aging of blood vessels

Chronic use of antacid drugs may speed up aging of blood vessels

Acid suppression drugs frequently prescribed for high-risk newborns, study shows

Acid suppression drugs frequently prescribed for high-risk newborns, study shows

Camber Pharmaceuticals releases generic version of Nexium (Esomeprazole) capsules

Camber Pharmaceuticals releases generic version of Nexium (Esomeprazole) capsules

Mylan announces launch of Esomeprazole Magnesium Delayed-release Capsules USP in U.S.

Mylan announces launch of Esomeprazole Magnesium Delayed-release Capsules USP in U.S.

Proton pump inhibitors linked to increased risk of heart attack

Proton pump inhibitors linked to increased risk of heart attack

ViiV Healthcare initiates Phase III trial to evaluate dolutegravir and rilpivirine in HIV patients

ViiV Healthcare initiates Phase III trial to evaluate dolutegravir and rilpivirine in HIV patients

St. John Hospital first in Michigan to offer new alternative treatment for acid reflux disease

St. John Hospital first in Michigan to offer new alternative treatment for acid reflux disease

MHRA reclassifies Pfizer’s Nexium Control as an OTC treatment for heartburn

MHRA reclassifies Pfizer’s Nexium Control as an OTC treatment for heartburn

Antacid medicines improve overall survival in patients with head and neck cancer

Antacid medicines improve overall survival in patients with head and neck cancer

LINX Reflux Management System safe for patients suffering from GERD, shows new data

LINX Reflux Management System safe for patients suffering from GERD, shows new data

Generic drug delays cost U.S. payers millions

Generic drug delays cost U.S. payers millions