Nucleic Acid News and Research

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New and efficient method Monkeypox virus sequencing

In a recent study posted to the medRxiv* preprint server, Spanish researchers described a new enrichment method for metagenomic sequencing of the monkeypox virus (MPXV).

2 Aug 2022

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

The role of cellular or cytokine response and vaginal microbiome dysbiosis in the clearance, persistence, and recurrence of HPV infection

Researchers have reviewed the role of cytokine or cellular response and vaginal microbiome dysbiosis in the persistence, clearance, and recurrence of HPV infection

28 Jul 2022

Investigating an effective linear deoxyribonucleic acid COVID-19 vaccine option for domestic cats

In a new study, investigators studied a linear deoxyribonucleic acid (linDNA) SARS-CoV-2 vaccine option in felines.

27 Jul 2022

Innovative technology reveals new insights into cellular reservoirs of HIV

In a presentation today at AIDS 2022, the 24th International AIDS Conference in Montreal, scientists with the National Institute of Allergy and Infectious Diseases' (NIAID) Vaccine Research Center (VRC) and their collaborators described how their use of cutting-edge technology revealed new insights into cellular reservoirs of HIV and what those observations could mean for the next steps in HIV cure research. NIAID is part of the National Institutes of Health.

27 Jul 2022

Novel compound inhibits SARS-CoV-2 replication by binding a genome target

Researchers assessed the biodistribution and safety of SBCoV202, a novel antiviral agent based on antisense technology that can specifically and effectively bind to the SARS-CoV-2 genome target to inhibit SARS-CoV-2 replication.

27 Jul 2022

Scientists explore post-COVID-19 conditions among children

Scientists evaluated post coronavirus disease 2019 conditions across children 90 days following COVID-19.

27 Jul 2022

MolGen showcases its lab automation solutions at AACC in Chicago

MolGen B.V. of Veenendaal (NL), a global solutions provider of hardware, reagents, consumables, software and service for human and animal diagnostics, the agriculture and biotech industries, participates in the American Association for Clinical Chemistry Fair (AACC) in Chicago on July 24th - 28th, 2022.

From MolGen 25 Jul 2022

Microplate optimised for magnetic bead separations

Porvair Sciences has introduced a 96-well deep well microplate designed for labs using magnetic beads for nucleic acid purification, clean up and protein purifications.

From Porvair Sciences Limited 15 Jul 2022

New anticoagulant platform holds promise as a revolutionary advancement over the current blood thinners

While blood clotting is important to prevent blood loss and for our immunity, coagulation also can cause health issues and even death. Currently, one in four people worldwide dies from diseases and conditions caused by blood clots.

15 Jul 2022

The disease burden and clinical severity of the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Shanghai

Researchers estimated the severity and burden of COVID-19 in a recent outbreak in Shanghai, China.

14 Jul 2022

Doggybone DNA COVID-19 vaccine can effectively neutralize SARS-CoV-2 variants

Researchers assessed the efficacy of the novel SARS-CoV-2 doggybone deoxyribonucleic acid (DNA) vaccine.

13 Jul 2022

Novel COVID-19 antibody delivery approach advances to clinical trials

Under a Defense Advanced Research Projects Agency (DARPA) and Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense (JPEO-CBRND) funded program, a novel COVID-19 antibody delivery approach has advanced to clinical trials.

7 Jul 2022

2022 monkeypox presents with new symptoms

In a recent study published in The Lancet Infectious Diseases, researchers described the clinical and demographical characteristics of monkeypox virus infections among individuals attending sexual health centers in the United Kingdom (UK).

6 Jul 2022

Beyond COVID-19: the potential future applications of mRNA vaccines

Researchers described the production, mechanisms, and potential applications of mRNA vaccines.

6 Jul 2022

LMU cell biologists show how interactions between RNA-binding proteins affect synaptic plasticity in neurons

LMU scientists demonstrate that interactions between RNA-binding proteins affect translation and consequently the complexity of neurons.

4 Jul 2022

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Researchers developed a new detection assay for SARS-CoV-2.

1 Jul 2022

Effectiveness of Pfizer-BioNTech’s BNT162b2 vaccine against SARS-CoV-2 Delta and Omicron variants among teens

Researchers evaluated Pfizer-BioNTech’s BNT162b2 vaccine effectiveness after two and three doses against SARS-CoV-2 variants of concern such as Delta and in Canadian adolescent community residents.

30 Jun 2022

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

In a recent study posted to the medRxiv* pre-print server, researchers in the United States characterized differential host immune responses in acute coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) to inform future development of novel biomarkers for both diseases.

23 Jun 2022

How effective are mRNA COVID-19 vaccine boosters against Omicron?

In a recent study posted to the medRxiv* preprint server, researchers University of Washington, University of Michigan, Duke University, and Veterans Affairs Portland Healthcare System assessed the effectiveness of the coronavirus disease 2019 (COVID-19) booster vaccines.

19 Jun 2022

Nucleic Acid News and Research

New and efficient method Monkeypox virus sequencing

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

The role of cellular or cytokine response and vaginal microbiome dysbiosis in the clearance, persistence, and recurrence of HPV infection

Investigating an effective linear deoxyribonucleic acid COVID-19 vaccine option for domestic cats

Innovative technology reveals new insights into cellular reservoirs of HIV

Novel compound inhibits SARS-CoV-2 replication by binding a genome target

Scientists explore post-COVID-19 conditions among children

MolGen showcases its lab automation solutions at AACC in Chicago

Microplate optimised for magnetic bead separations

New anticoagulant platform holds promise as a revolutionary advancement over the current blood thinners

The disease burden and clinical severity of the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Shanghai

Doggybone DNA COVID-19 vaccine can effectively neutralize SARS-CoV-2 variants

Novel COVID-19 antibody delivery approach advances to clinical trials

2022 monkeypox presents with new symptoms

Beyond COVID-19: the potential future applications of mRNA vaccines

LMU cell biologists show how interactions between RNA-binding proteins affect synaptic plasticity in neurons

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Effectiveness of Pfizer-BioNTech’s BNT162b2 vaccine against SARS-CoV-2 Delta and Omicron variants among teens

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

How effective are mRNA COVID-19 vaccine boosters against Omicron?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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