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Beyond COVID-19: the potential future applications of mRNA vaccines

Researchers described the production, mechanisms, and potential applications of mRNA vaccines.

6 Jul 2022

LMU cell biologists show how interactions between RNA-binding proteins affect synaptic plasticity in neurons

LMU scientists demonstrate that interactions between RNA-binding proteins affect translation and consequently the complexity of neurons.

4 Jul 2022

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Researchers developed a new detection assay for SARS-CoV-2.

1 Jul 2022

Effectiveness of Pfizer-BioNTech’s BNT162b2 vaccine against SARS-CoV-2 Delta and Omicron variants among teens

Researchers evaluated Pfizer-BioNTech’s BNT162b2 vaccine effectiveness after two and three doses against SARS-CoV-2 variants of concern such as Delta and in Canadian adolescent community residents.

30 Jun 2022

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

In a recent study posted to the medRxiv* pre-print server, researchers in the United States characterized differential host immune responses in acute coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) to inform future development of novel biomarkers for both diseases.

23 Jun 2022

How effective are mRNA COVID-19 vaccine boosters against Omicron?

In a recent study posted to the medRxiv* preprint server, researchers University of Washington, University of Michigan, Duke University, and Veterans Affairs Portland Healthcare System assessed the effectiveness of the coronavirus disease 2019 (COVID-19) booster vaccines.

19 Jun 2022

The potential mechanisms of SARS-CoV-2 to induce DNA damage

Researchers described potential mechanisms of coronaviruses that could lead to DNA damage and the potential link between SARS-CoV-2 activity and such mechanisms.

14 Jun 2022

University screening programs gave scientists early insights about omicron’s spread

Omicron was first reported in South Africa on Nov. 24, 2021, and within mere days it was already making the rounds in the United States, spiking SARS-CoV-2 case numbers as it infiltrated every school, restaurant, and family gathering. But when exactly did omicron unseat the delta variant to become dominant? And how quickly did it actually take over?

9 Jun 2022

New fluorogenic probe could quickly detect the presence of influenza A virus

The influenza A virus, which is responsible for seasonal flu outbreaks, is also the only influenza virus that has previously caused flu pandemics.

6 Jun 2022

Nanotechnology enhanced DNA-chip for SARS-CoV-2 detection with variant differentiation

Researchers differentiated between SARS-CoV-2 variants using nanotechnology.

26 May 2022

FIND to present an overview of disease surveillance status and diagnostics to combat monkeypox

Diagnostic testing and disease surveillance are back in the spotlight as scientists and public health workers closely monitor the current outbreak of monkeypox that has emerged in cities across Europe, the US, Australia and Canada.

26 May 2022

Development of a rapid, inexpensive and highly accurate diagnostic method to fight African Swine Fever

While the attention of public health authorities has been rivetted on the current COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, many other viruses have been stealthily circling the globe, causing serious disease and death in humans and other animals.

25 May 2022

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reviewed available mucosal vaccines discussing the current challenges and ways to advance the existing approaches.

25 May 2022

Findings from the CoVaccS study on parental intention to vaccinate children against COVID

In the current preprint posted to the medRxiv* server, the researchers looked at UK parental intention to vaccinate their children during a time of selective pediatric vaccination.

24 May 2022

Researchers discover osteogenetic oligodeoxynucleotide that promotes bone differentiation

Bone tissue homeostasis is maintained by a balance between bone formation by osteoblasts and bone resorption by osteoclasts.

23 May 2022

Antibiotic rifampicin attenuates C9orf72-linked dementia in genetically modified mice

What did Stephen Hawking and Mao Zedong have in common? They both suffered from Amyotrophic Lateral Sclerosis (ALS), a cure for which remains elusive. Scientists from Osaka Metropolitan University took an important step toward prevention of ALS and another brain disorder called Frontotemporal dementia (FTD) with their research on the effects of the antibiotic rifampicin on genetically modified mice.

23 May 2022

Health authorities must revolutionize testing to deal with future covid-19 prevalence

Dealing with lower covid-19 levels will require improved understanding of what diagnostic tests are best used for. It will also need more accurate tests, but as testing demand will fall, delivering that needs incentive-based support.

23 May 2022

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

A new study aimed to evaluate the immunostimulatory potential of mRNA vaccines in AGS patients.

23 May 2022

Study shows the QuickNavi-COVID19 Ag test has a high diagnostic performance for SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in nasopharyngeal samples

Researchers evaluated the diagnostic performance of a COVID-19 antigen test during the recent surge caused by the SARS-CoV-2 Omicron variant.

23 May 2022

RNA binding-induced structural dynamics of SARS-CoV-2 nucleocapsid protein

Researchers predict structure models of the full-length SARS-CoV-2 N protein in both the presence and absence of RNA.

19 May 2022

Nucleic Acid News and Research

Beyond COVID-19: the potential future applications of mRNA vaccines

LMU cell biologists show how interactions between RNA-binding proteins affect synaptic plasticity in neurons

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Effectiveness of Pfizer-BioNTech’s BNT162b2 vaccine against SARS-CoV-2 Delta and Omicron variants among teens

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

How effective are mRNA COVID-19 vaccine boosters against Omicron?

The potential mechanisms of SARS-CoV-2 to induce DNA damage

University screening programs gave scientists early insights about omicron’s spread

New fluorogenic probe could quickly detect the presence of influenza A virus

Nanotechnology enhanced DNA-chip for SARS-CoV-2 detection with variant differentiation

FIND to present an overview of disease surveillance status and diagnostics to combat monkeypox

Development of a rapid, inexpensive and highly accurate diagnostic method to fight African Swine Fever

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Findings from the CoVaccS study on parental intention to vaccinate children against COVID

Researchers discover osteogenetic oligodeoxynucleotide that promotes bone differentiation

Antibiotic rifampicin attenuates C9orf72-linked dementia in genetically modified mice

Health authorities must revolutionize testing to deal with future covid-19 prevalence

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

Study shows the QuickNavi-COVID19 Ag test has a high diagnostic performance for SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in nasopharyngeal samples

RNA binding-induced structural dynamics of SARS-CoV-2 nucleocapsid protein

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Realizing the Importance of Medical Electronic Devices

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