Nucleotide News and Research

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MCG selected as designated laboratory for NCI-MATCH trial

The Georgia Esoteric and Molecular Laboratory at the Medical College of Georgia at Augusta University has been selected as a designated laboratory for the National Cancer Institute's Molecular Analysis for Therapy Choice, or MATCH trial, which is assessing the effectiveness of targeting cancer-causing gene changes rather than cancer type.

1 Nov 2018

Scientists decode the longest ever continuous DNA sequence

Scientists have decoded the longest continuous DNA sequence to date, measuring around 10,000 times longer than normal sequencing reads.

1 Nov 2018

Study finds kill code mechanism embedded in every cell to extinguish cancer

A kill code is embedded in every cell in the body whose function may be to cause the self-destruction of cells that become cancerous, reports a new Northwestern Medicine study. As soon as the cell's inner bodyguards sense it is mutating into cancer, they punch in the kill code to extinguish the mutating cell.

29 Oct 2018

Scientists determine normal function of gene associated with ALS and FTD

The normal function of a gene associated with the neurodegenerative diseases amyotrophic lateral sclerosis and frontotemporal dementia has been determined for the first time by University of Bath scientists.

24 Oct 2018

Understanding of metal-free enzymes used by bacteria could lead to new effective antibiotics

Some bacterial pathogens, including those that cause strep throat and pneumonia, are able to create the components necessary to replicate their DNA without the usually required metal ions.

19 Oct 2018

Duke researchers find way to detect blood doping in athletes

A Duke University research team has found a way to help sporting officials detect whether an athlete's blood has been doped by an infusion of their own stored blood.

19 Oct 2018

Next-generation RNA sequencing technology sheds new light on human mitochondrial diseases

The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer RNA (tRNA) molecules to couple recognition of the genetic code with the cognate amino acid, which are the building blocks of proteins.

19 Oct 2018

Genetically modifying zebrafish provides numerous, highly accurate disease models

Research published today describes how zebrafish can be genetically engineered to produce more accurate models of human disease.

18 Oct 2018

DNA Script successfully synthesizes world's first 150-nucleotide strand of DNA

DNA Script, the global leader in the development of enzymatic DNA synthesis, today announced that it has successfully synthesized the world's first 150-nucleotide strand of DNA by de novo enzymatic synthesis.

3 Oct 2018

NorthShore and Ambry announce launch of new test to assess prostate cancer risk

NorthShore University HealthSystem's Center for Personalized Medicine and Ambry Genetics Corporation, announced today the launch of AmbryScore for prostate cancer risk.

26 Sep 2018

Scientist intends to fight pathogenic bacteria with viruses

Dr. Li Deng of Helmholtz Zentrum München has been awarded a Starting Grant of the European Research Council. The scientist intends to tackle antimicrobial resistance by fighting bacteria with their natural enemies - the viruses. The grant is endowed with nearly 1.5 million euros for five years.

21 Sep 2018

Researchers acquire new insights into DNA polymerases

Complex biological systems can be described as a network of chemical processes that take place in molecules. The scientists of the "ChemLife" research initiative at the University of Konstanz are working together in an equally active network with dynamic interconnections - both subject-specific and interdisciplinary.

19 Sep 2018

Researchers find way to map mysterious content of non-coding RNA

Researchers from the University of North Carolina have found a way of categorising long non-coding RNAs (lnc-RNAs) by their probable function.

18 Sep 2018

Health Care Apps and the Empowered Patient

An interview with Evergreen Life, discussing the importance of patient empowerment and how technology is allowing the NHS take a holistic approach to care.

From Evergreen Life 12 Sep 2018

Study links spinal muscular atrophy disease expression with haplotypes

A natural history study has provided the first comprehensive clinical description of spinal muscular atrophy within the Amish and Mennonite communities and correlates ancestral chromosome 5 haplotypes and SMN2 copy number with disease severity.

7 Sep 2018

Natural plant compound exploits newly identified Achilles' heel in uveal melanoma

A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. Louis.

6 Sep 2018

Researchers discover natural plant compound that shuts down uveal melanoma cell growth

A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma.

6 Sep 2018

Severity of asthma depends on genetic profile and air pollution

Asthma patients, with a specific genetic profile, exhibit more intense symptoms following exposure to traffic pollution, according to researchers at the National Institutes of Health and collaborators. The study appeared online in Scientific Reports.

31 Aug 2018

NRGene constructs comprehensive soy genome diversity-haplotype database

NRGene, the leading genomic big data company, has constructed a comprehensive soy genome diversity-haplotype database based on results from GenoMAGIC™, allowing commercial and academic researchers never-before-available insights into the genomic diversity within the soybean crop.

28 Aug 2018

Genetic interindividual variability influences nutritional requirements

Approximately 0.1%: that is the average genetic difference between two individuals. This small percentage is responsible for the variations of certain physical traits, such as eyes, hair, and height, but also for differences in our susceptibility to certain diseases and our capacity to absorb vitamins and phytomicronutrients, involved in the prevention of chronic disease.

24 Aug 2018