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Geldanamycin degrades VEGFR2 protein that triggers blood vessel growth

The drug, geldanamycin, is well known for attacking a protein associated with the spread of breast cancer. However, a laboratory-based study found it also degraded a different protein that triggers blood vessel growth.

6 Nov 2012

Some types of bariatric surgery may cause bone loss, say endocrinologists

Bariatric surgery, which significantly curtails the amount of food a person can eat, is the most effective treatment against obesity and is being recognized as a potentially valuable tool in the fight against diabetes related to obesity.

3 Nov 2012

Mass spectrometry can help visualize how drugs work inside living cells to kill infectious microbes

Weill Cornell Medical College researchers report that mass spectrometry, a tool currently used to detect and measure proteins and lipids, can also now allow biologists to "see" for the first time exactly how drugs work inside living cells to kill infectious microbes.

3 Nov 2012

Hospital for Special Surgery physical therapist offers marathon recovery tips

Close to 47,000 runners have spent the past several months training for the ING New York City Marathon. Once they have completed the race and achieved their goals, there are measures they can take to facilitate recovery, decrease post-race discomfort, and return to running without injury.

3 Nov 2012

Malarial drug shows promise in stopping breast cancer

A malarial drug is showing promise in stopping breast cancer before it starts, Mason researchers are discovering during a clinical trial.

2 Nov 2012

Ischemic stroke: an interview with Dr Gregory Ford

A stroke is a sudden interruption of blood flow to the brain which deprives the brain of oxygen and nutrients. Approximately two millions brain cells die each minute during a stroke. This can lead to brain damage, physical and mental disability and death.

1 Nov 2012

Oily fish consumption may reduce risk of stroke

Eating at least two servings of oily fish a week is moderately but significantly associated with a reduced risk of stroke, finds a study published on bmj.com today.

31 Oct 2012

Intravenous catheter replacement: an interview with Claire Rickard

Peripheral intravenous catheters (“IV drips”) are small plastic tubes inserted into veins, most frequently in the hand or arm.

30 Oct 2012

Mouse model may provide clues on mechanism that links diabetes and aging to Alzheimer's

Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. In a new study published in Aging Cell, researchers at the Salk Institute for Biological Studies show, for the first time, that diabetes enhances the development of aging features that may underlie early pathological events in Alzheimer's.

29 Oct 2012

Researchers identify genes that control regeneration of the intestine in planarian flatworms

Researchers report in the journal Developmental Cell that they have identified genes that control growth and regeneration of the intestine in the freshwater planarian Schmidtea mediterranea.

26 Oct 2012

Targeted deletion of major VEGF gene in mice induces vision loss

Millions of people with "wet" macular degeneration are prescribed a class of medication known as anti-VEGF drugs. But now scientists at The Scripps Research Institute (TSRI) have found that a drastic reduction of VEGF activity may do more harm than good.

26 Oct 2012

New NCAA feeding protocol for athletes

Sports registered dietitians working in college and professional sports are asking the NCAA to toss out rules that restrict athletes to only one meal per day and instead permit unlimited interval feedings as needed throughout the day to fully restore athletes and make them 'whole again.'

26 Oct 2012

Pica and geophagy far more prevalent in Madagascar

Though it was identified as a disorder as early as the 14th century, pica, or the eating of non-food items, has for years believed to be all but non-existent in a few corners of the globe - a 2006 study that reviewed research on pica found just four regions - the South of South America, Japan, Korea and Madagascar -where the behavior had never been observed.

25 Oct 2012

Article describes most promising strategies for vascularization of bone tissue substitutes

New, advanced techniques are needed that can mimic the normal blood supply that feeds natural bone to improve the viability and success of restorative procedures to replace damaged or diseased bone tissue using engineered constructs. A comprehensive review article describing the most promising strategies for vascularization of bone tissue substitutes is published in Tissue Engineering, Part B: Reviews, a peer-reviewed journal from Mary Ann Liebert, Inc.

25 Oct 2012

Meat from wild animals is increasingly important in central Africa

Animals like antelope, frogs and rodents may be tricky to catch, but they provide protein in places where traditional livestock are scarce. According to the authors of a new paper in Animal Frontiers, meat from wild animals is increasingly important in central Africa.

25 Oct 2012

Chronic electrical stimulation may help treat gastroparesis symptoms

Diabetic patients who suffer from a common complication of diabetes called gastroparesis may find that chronic electrical stimulation (ES) at specific acupuncture points could relieve gastroparesis symptoms such as nausea, vomiting, early satiety, abdominal fullness, upper abdominal pain and bloating, according to study results unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas.

22 Oct 2012

CNN program examines childhood stunting

In this episode of CNN's "Amanpour," correspondent Christiane Amanpour talks with UNICEF Executive Director Anthony Lake and Grammy award-winning singer and songwriter Angelique Kidjo, a UNICEF goodwill ambassador, about childhood stunting, which "threatens 180 million children below the age of five all over the world."

19 Oct 2012