Nutrients News and Research

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New genes that regulate longevity

In an effort to understand the molecular mechanisms that control aging, Howard Hughes Medical Institute researchers and their colleagues have now uncovered 10 new genes that regulate longevity in yeast. The studies also suggest a new model for how aging is slowed when caloric intake is restricted.

20 Nov 2005

Biologically engineered blood vessels now an option in cardiac bypass

The first-ever human use of completely biologically engineered blood vessels grown from a person's own cells could be an option for people who have vessels too damaged for heart bypass, researchers reported at the American Heart Association's Scientific Sessions 2005.

16 Nov 2005

Gene therapy potential of the protein vasostatin for treatment of pancreatic cancer

A gene responsible for the production of a protein called vasostatin may prove a promising new way of treating pancreatic cancer, suggests research published ahead of print in Gut.

15 Nov 2005

FLT-1 blockers, cutting the legs of leukaemia

Leukaemia is characterised by an uncontrolled growth of abnormal blood cells in the bone marrow (BM).

14 Nov 2005

Biomedical device allows stem cells derived from adult bone marrow to be grown in sufficient quantities to permit far more research

Human stem cells offer tremendous hope for the development of revolutionary medical treatments for these and a variety of other human health problems.

14 Nov 2005

New understanding of the disease process involved in atherosclerosis

The progression of the artery-clogging disease atherosclerosis is linked to the inability of specialized bone marrow cells to continuously repair damage to the arterial lining, Duke University Medical Center researchers have demonstrated.

13 Nov 2005

Phenolic compounds in olive oil may explain cardiovascular health benefits associated with Mediterranean Diet

Phenolic compounds in olive oil, which have antioxidant, anti-inflammatory and anti-clotting properties, may explain cardiovascular health benefits associated with the so-called Mediterranean Diet, according to a new study in the Nov. 15, 2005, issue of the Journal of the American College of Cardiology.

13 Nov 2005

Cellular signal may determine life or death for damaged brain cells

Scientists at the Universities of Heidelberg and Ulm and a unit of the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, have discovered that a specific signal within brain cells may determine whether they live or die after a stroke.

13 Nov 2005

Human umbilical cord blood cells may widen treatment window for stroke

An experimental treatment that spares disability from acute stroke may be delivered much later than the current three-hour treatment standard – a potential advance needed to benefit more stroke victims.

13 Nov 2005

Vitamin D sufficiency may be more important than high calcium intake for maintaining calcium metabolism

Calcium intake levels of more than 800 mg/day may be unnecessary for maintaining calcium metabolism if vitamin D status is adequate, according to a study in the November 9 issue of JAMA: The Journal of the American Medical Association.

10 Nov 2005

New understanding of sphingosine kinases called SphK1 and SphK2

Virginia Commonwealth University Massey Cancer Center researchers have found that two enzymes that catalyze the same reaction and produce the same product have opposite effects on cell growth and death.

7 Nov 2005

Fundamental insight about protein evolution

While searching for new targets for malaria drugs and vaccines, a team including a Howard Hughes Medical Institute (HHMI) medical student fellow reached a fundamental insight about evolution: different species make use of similar sets of proteins in different ways.

3 Nov 2005

First study to confirm the benefit of anti-angiogenic therapy in patients with breast cancer

Results from the first and only interim analysis of an important trial assessing the potential of Herceptin (trastuzumab) to improve disease-free survival (DFS) in HER-2 positive breast cancer patients after adjuvant chemotherapy, have shown that Herceptin affords a significant survival advantage.

1 Nov 2005

Scientists unravel complex mechanisms in the brain that regulate body weight

Scientists are one step closer to unraveling the complex mechanisms in the brain that regulate body weight. Working with mice -- whose appetites are controlled by systems very similar to those in humans – they have identified a specific type of neuron that is essential for feeding behavior.

30 Oct 2005

Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis

"Recurrent wheeze and breathlessness are common in people with cystic fibrosis, and bronchodilators are commonly prescribed," according to lead author Clare Halfhide, M.D., of the Royal Liverpool Children's Hospital in England. "Despite their wide-scale and often long-term use, there is limited objective evidence about their efficacy in cystic fibrosis."

25 Oct 2005

Surgery to treat obesity far more risky for men

Researchers say that using stomach-shrinking surgery to treat severe obesity is riskier than previously thought for men, the elderly and people with conditions such as hypertension.

19 Oct 2005

Hormone responsible for types of high blood pressure could also cause preeclampsia

Researchers at the University of Cincinnati (UC) Academic Health Center have found evidence of a hormone they say is responsible for certain types of high blood pressure (hypertension), and could also cause preeclampsia, a potentially dangerous condition that occurs during pregnancy.

17 Oct 2005

High fat, low carb diet may help Alzheimer's sufferers

Scientists have discovered that a high fat, low carbohydrate diet improves Alzheimer's disease in mice and say the study results may also have implications for dieters.

17 Oct 2005

High fat, low carb diet improves Alzheimer's disease in mice

A report published today in the BioMed Central, open access journal Nutrition and Metabolism, showed that a brain protein, amyloid-beta, which is an indicator of Alzheimer's disease, is reduced in mice on the so-called ketogenic diet.

16 Oct 2005

$Older men with Parkinson's disease at increased risk of bone fractures$

Older men with Parkinson's disease at increased risk of bone fractures

Researchers found that Parkinson’s disease (PD) in older men is associated with lower bone mineral density and suggested that physicians should consider screening older male patients with PD for osteoporosis.

12 Oct 2005

Nutrients News and Research

New genes that regulate longevity

Biologically engineered blood vessels now an option in cardiac bypass

Gene therapy potential of the protein vasostatin for treatment of pancreatic cancer

FLT-1 blockers, cutting the legs of leukaemia

Biomedical device allows stem cells derived from adult bone marrow to be grown in sufficient quantities to permit far more research

New understanding of the disease process involved in atherosclerosis

Phenolic compounds in olive oil may explain cardiovascular health benefits associated with Mediterranean Diet

Cellular signal may determine life or death for damaged brain cells

Human umbilical cord blood cells may widen treatment window for stroke

Vitamin D sufficiency may be more important than high calcium intake for maintaining calcium metabolism

New understanding of sphingosine kinases called SphK1 and SphK2

Fundamental insight about protein evolution

First study to confirm the benefit of anti-angiogenic therapy in patients with breast cancer

Scientists unravel complex mechanisms in the brain that regulate body weight

Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis

Surgery to treat obesity far more risky for men

Hormone responsible for types of high blood pressure could also cause preeclampsia

High fat, low carb diet may help Alzheimer's sufferers

High fat, low carb diet improves Alzheimer's disease in mice

Older men with Parkinson's disease at increased risk of bone fractures

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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