OCT News and Research

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Diabetes complications linked to increased risk of colorectal cancer recurrence and death

Complications of diabetes can have numerous negative health effects, from impaired vision and nerve damage to kidney dysfunction and heart disease. In an analysis of information on adults with colorectal cancer, patients who also had diabetes-;particularly those with diabetic complications-;faced a higher risk of dying early.

24 Oct 2023

Perioperative durvalumab may change standard-of-care for patients with resectable lung cancer

A regimen of pre-surgical immunotherapy and chemotherapy followed by post-surgical immunotherapy significantly improved event-free survival (EFS) and pathologic complete response (pCR) rates compared to chemotherapy alone for patients with operable non-small cell lung cancer (NSCLC), according to results of a Phase III trial reported by researchers at The University of Texas MD Anderson Cancer Center.

24 Oct 2023

Research suggests shorter isolation periods for children with COVID-19

School policies that require students with COVID-19 to stay out of the classroom for five days are more than sufficient.

24 Oct 2023

Researchers discover new way to trigger programmed cell death in cancer cells

A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die.

24 Oct 2023

Study reveals unexpected role of pulmonary ionocytes in lung function

A new study by University of Iowa researchers finds that rare lung cells known as pulmonary ionocytes facilitate the absorption of water and salt from the airway surface.

24 Oct 2023

Neoadjuvant pembrolizumab achieves major pathologic response in more than half of patients with resectable melanoma

In exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major pathologic response in more than half of surgical specimens taken from patients who had been treated with neoadjuvant (pre-operative) pembrolizumab.

24 Oct 2023

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

24 Oct 2023

New "pseudo cell" formulation could revolutionize treatment of vitreoretinal diseases

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and Beijing Chaoyang Hospital have developed a new "pseudo cell" formulation based on self-healing microcapsule-loading exosomes to treat diverse vitreoretinal diseases.

24 Oct 2023

New method provides valuable insights into the brain's noradrenaline system

An international team of researchers has provided valuable insights into the brain's noradrenaline (NA) system, which has been a longtime target for medications to treat attention-deficit/hyperactivity disorder, depression, and anxiety.

24 Oct 2023

Study reveals an alternate origin of brain mosaicism in some children with focal epilepsy

In most people, every cell in their body contains the same genetic information. However, sometimes people can have two or more genetically different sets of cells.

24 Oct 2023

Heated yoga sessions linked to greater reductions in depressive symptoms

In a randomized controlled clinical trial of adults with moderate-to-severe depression, those who participated in heated yoga sessions experienced significantly greater reductions in depressive symptoms compared with a control group.

24 Oct 2023

Apoptotic cells play key role in hair follicle regression

A new research paper was published in Oncotarget's Volume 14 on October 19, 2023, entitled, "Apoptotic cells may drive cell death in hair follicles during their regression cycle."

24 Oct 2023

Homeless people have a 16-fold higher rate of sudden death from heart attacks

A study led by UC San Francisco has found that people who are experiencing homelessness have a 16-fold higher rate of sudden death from heart attacks, as well as other causes.

24 Oct 2023

Study shows TAVR as a good alternative to open-heart surgery in younger patients with aortic stenosis

Patients with a dysfunctional aortic heart valve who received a new, prosthetic valve through a minimally invasive procedure had similar outcomes at five years as those who underwent open-heart surgery, a new study shows.

24 Oct 2023

Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

A secondary analysis from the SWOG S0931 EVEREST trial has found that in the subgroup of patients with clear-cell renal cell carcinoma (RCC) who were at very-high risk of recurrence, those who were treated with everolimus after surgery had a statistically significant improvement in recurrence-free survival compared to patients getting placebo after surgery.

22 Oct 2023

Why is finding covid shots for young children still so hard?

On Sept. 12, the Centers for Disease Control and Prevention recommended the next round of covid shots for everyone 6 months and older.

20 Oct 2023

Scientists uncover a group of immune cells that may drive severe asthma in older men

Scientists from La Jolla Institute for Immunology (LJI) and The University of Southampton, UK, have uncovered a group of immune cells that may drive severe asthma.

20 Oct 2023

Scientists develop gene therapy approach for rare paralyzing disease

The 50 families stretch from the Netherlands and the United Kingdom to the United States and China. Each family has a child who is paralyzed from a mutation in a single gene named Contactin-Associated Protein 1 (Cntnap1).

20 Oct 2023

New method uses magnets to align muscle cells

Stimulating muscle fibers with magnets causes them to grow in the same direction, aligning muscle cells within tissue, Massachusetts Institute of Technology (MIT) and Boston University investigators report October 20 in the journal Device.

20 Oct 2023

Study reveals how tuberculosis bacteria form cords to resist antibiotics

The ability of Mycobacterium tuberculosis (MTB), a serious respiratory infection, to form snake-like cords was first noted nearly 80 years ago. In a study published October 20 in the journal Cell, investigators report the biophysical mechanisms by which these cords form and demonstrate how several generations of dividing bacteria hang together to create these structures that enable resistance to antibiotics.

20 Oct 2023

OCT News and Research

Diabetes complications linked to increased risk of colorectal cancer recurrence and death

Perioperative durvalumab may change standard-of-care for patients with resectable lung cancer

Research suggests shorter isolation periods for children with COVID-19

Researchers discover new way to trigger programmed cell death in cancer cells

Study reveals unexpected role of pulmonary ionocytes in lung function

Neoadjuvant pembrolizumab achieves major pathologic response in more than half of patients with resectable melanoma

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

New "pseudo cell" formulation could revolutionize treatment of vitreoretinal diseases

New method provides valuable insights into the brain's noradrenaline system

Study reveals an alternate origin of brain mosaicism in some children with focal epilepsy

Heated yoga sessions linked to greater reductions in depressive symptoms

Apoptotic cells play key role in hair follicle regression

Homeless people have a 16-fold higher rate of sudden death from heart attacks

Study shows TAVR as a good alternative to open-heart surgery in younger patients with aortic stenosis

Everolimus after surgery may benefit patients with very-high-risk clear cell renal cell carcinoma

Why is finding covid shots for young children still so hard?

Scientists uncover a group of immune cells that may drive severe asthma in older men

Scientists develop gene therapy approach for rare paralyzing disease

New method uses magnets to align muscle cells

Study reveals how tuberculosis bacteria form cords to resist antibiotics

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Expanding research and clinical options for children with cancer

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