Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Scientists observe gene activity outside the body

Researchers at Jefferson Medical College and Jefferson's Kimmel Cancer Center in Philadelphia have used PET imaging to see hyperactive cancer genes inside breast tumors in laboratory animals, marking the first time such gene activity has been observed from outside the body.

29 Nov 2007

MIT radar technology fights breast cancer

Treating breast cancer with a type of heat therapy derived from MIT radar research can significantly increase the effectiveness of chemotherapy, according to results from the fourth clinical trial of the technique reported online Nov. 25 in the journal Cancer Therapy.

27 Nov 2007

Wyeth receives European approval for TORISEL

Wyeth Pharmaceuticals, a division of Wyeth, has announced that the European Commission has approved TORISEL (temsirolimus) for the first-line treatment of patients with advanced renal cell carcinoma (RCC) who have at least three of six prognostic risk factors. TORISEL is the only approved cancer therapy that specifically inhibits the mTOR (mammalian target of rapamycin) kinase, an important regulator of cell proliferation, cell growth and cell survival.

27 Nov 2007

Whole-body positron emission tomography can reassure cervical cancer patients

Whole-body PET (positron emission tomography) scans done three months after completion of cervical cancer therapy can ensure that patients are disease-free or warn that further interventions are needed, according to a study at Washington University School of Medicine in St. Louis.

21 Nov 2007

Bortezomib pushes cancer cells into overdrive, so that they self-destruct

University of Michigan Comprehensive Cancer Center researchers have discovered that bortezomib, a promising cancer drug, is able to strike a blow against melanoma tumor cells by revving up the action of a cancer-promoting gene.

21 Nov 2007

Schering-Plough acquires Organon BioSciences

Schering-Plough Corporation has announced that it has completed the acquisition of Organon BioSciences N.V., creating a stronger combined company with broader human and animal health portfolios, an enhanced pipeline and increased R&D capabilities. Schering-Plough's agreement to acquire Organon BioSciences was announced on March 12, 2007.

20 Nov 2007

New device delivers radiation therapy to specific tumor sites

Physicians at the Rebecca and John Moores UCSD Cancer Center will present the initial outcomes of their use of a new device that delivers radiation therapy to a specific tumor site at the annual meeting of the Radiological Society of North America (RSNA), November 25-30, 2007, in Chicago, Illinois.

19 Nov 2007

U.S. approval of Nexavar (sorafenib) for inoperable liver cancer

The U.S. Food and Drug Administration has approved Nexavar (sorafenib) for use in patients with a form of liver cancer known as hepatocellular carcinoma, when the cancer is inoperable.

19 Nov 2007

Pfizer to acquire Coley Pharmaceutical Group

Pfizer has announced that it has entered into an agreement to acquire Coley Pharmaceutical Group, a publicly-held biopharmaceutical company specializing in vaccine adjuvant technology and a new class of immunomodulatory drug candidates designed to fight cancers, allergy and asthma disorders, and autoimmune diseases.

19 Nov 2007

Avastin (bevacizumab) shows promise in phase II study of glioblastoma multiforme

Genentech, Inc. has announced that both study arms of a randomized, multi-center Phase II clinical study of Avastin (bevacizumab) administered alone or in combination with irinotecan chemotherapy demonstrated encouraging six-month progression-free survival (PFS) and objective response rate in patients with relapsed glioblastoma multiforme (GBM), the most common and aggressive type of brain cancer.

19 Nov 2007

Pre-malignant mammary lesions in dogs and humans display many of the same characteristics

...a discovery that could lead to better understanding of breast cancer progression and prevention for people and pets, said a Purdue University scientist from the School of Veterinary Medicine.

16 Nov 2007

More women opting to have both breasts removed when cancer has been found in only one breast

Researchers are reporting a 150 percent increase between 1998 and 2003 in American women opting to have both breasts removed when cancer has been found in only one breast—a procedure called contralateral prophylactic mastectomy (CPM).

16 Nov 2007

Freeze-dried grape powder blocks genes linked to colon cancer

Low doses of freeze-dried grape powder inhibit genes linked to the development of sporadic colorectal cancer, University of California, Irvine cancer researchers found.

15 Nov 2007

Captopril may limit radiation kidney damage in bone marrow transplant patients

Researchers at the Medical College of Wisconsin in Milwaukee have found that the risk of radiation injury in normal tissue after exposure may be reduced by a drug in common use. Their study in press appears in the on line issue of the International Journal of Radiation Oncology, Biology and Physics.

15 Nov 2007

GPRC5A gene found to be a tumor-suppressor for lung cancer

The GPRC5A gene, which is under-expressed in human lung cancer cells, suppresses lung tumors in mouse models and could provide a key to attacking lung cancer in humans, researchers at The University of Texas M. D. Anderson Cancer Center report in the Nov. 21 edition of The Journal of the National Cancer Institute.

14 Nov 2007

Tumor-suppressor gene for lung cancer identified

14 Nov 2007

Real-time 3-D analysis of breast cancer biopsies

A sophisticated microscope that offers a “real-time” 3-D analysis of tissue samples might, in the future, reduce the number of needle biopsies traditionally needed from women suspected of having breast cancer, according to recent research published at Georgetown University Medical Center's Lombardi Comprehensive Cancer Center.

14 Nov 2007

Is the inability to express emotions hereditary?

The inability to express emotions (alexithymia) is thought to be hereditary. The largest study so far has provided new data in the current issue of Psychotherapy and Psychosomatics.

13 Nov 2007

Synthetic version of chlorotoxin shows promise in treatment of brain tumors

A drug developed and tested at UAB (University of Alabama at Birmingham) targeted at malignant brain tumors known as glioma has shown promising results in a Phase 1 trial, according to results presented at the American Society for Therapeutic Radiology and Oncology annual meeting.

6 Nov 2007

Li-Fraumeni syndrome found, for the first time, in Singapore

A rare hereditary disorder that strongly predisposes carriers to develop cancer at an early age has been found in an Asian female, report researchers at the American Association for Cancer Research Centennial Conference on Translational Cancer Medicine.

6 Nov 2007