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How best to treat chronic pain? The jury is still out

How best to alleviate chronic pain, a leading cause of disability and employee absenteeism, continues to perplex both patients and their doctors.

5 Jun 2008

Cephalon files patent infringement case against Watson Pharmaceuticals

Cephalon, Inc. today announced that it and its wholly-owned subsidiary CIMA LABS INC. have filed a lawsuit in U.S. District Court in Delaware against Watson Pharmaceuticals, Inc. and its wholly-owned subsidiary, Watson Laboratories, Inc., for infringement of U.S. Patent Nos. 6,200,604 and 6,974,590, which cover methods of use for the Cephalon product FENTORA(R) (fentanyl buccal tablet) [C-II].

3 Jun 2008

FDA approves Entereg (alvimopan) to restore bowel function

The U.S. Food and Drug Administration approved Entereg (alvimopan) today to accelerate the restoration of normal bowel function in patients 18 years and up who have undergone partial large or small bowel resection surgery. Entereg will be used in hospitalized patients who can receive no more than 15 doses.

20 May 2008

Big differences in depressed brains

Depressed people may have far fewer of the receptors for some of the brain's "feel good" stress-response chemicals than non-depressed people, new University of Michigan Depression Center research shows.

8 May 2008

Enkephalin pathway shows potential as new target for Alzheimer's

Alzheimer's disease (AD) is an incurable disease that is increasing in prevalence and will increase even more rapidly as the Baby Boom generation enters the age of highest risk. The available AD drugs are only partially effective in some patients. New strategies are urgently needed.

7 May 2008

FDA approves Relistor for opioid-induced constipation - helps reduce effects of drugs like morphine on bowel function

The U.S. Food and Drug Administration today approved Relistor (methylnaltrexone bromide) to help restore bowel function in patients with late-stage, advanced illness who are receiving opioids on a continuous basis to help alleviate their pain.

24 Apr 2008

Psychological intervention reduces postembolization pain

Psychological intervention has been shown to reduce the postembolization pain during hepatic arterial chemoembolizatiom therapy.

14 Mar 2008

Oral methadone dosing for chronic pain: practitioner's guide

Methadone, a strong opioid analgesic, is an effective and economical choice for the management of cancer pain and chronic noncancer pain, both as a first line medication and as a replacement opioid.

14 Mar 2008

Abuse of prescription medications linked to drug abuse among college students

College students who take frequently abused medications without a prescription appear to have a higher risk for drug abuse than those who use such therapies for medical reasons, according to a report in the March issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

4 Mar 2008

FDA approves Aloxi injection for prevention of postoperative nausea and vomiting

Eisai Corporation of North America, its U.S. subsidiary, MGI PHARMA, INC., and Helsinn Healthcare SA today announced that the U.S. Food and Drug Administration (FDA) has approved Aloxi (palonosetron hydrochloride) injection for the prevention of postoperative nausea and vomiting (PONV) for up to 24 hours following surgery.

4 Mar 2008

Epidemic of pain addressed by leading physicians

The public health problem that needs to be addressed next is the epidemic of pain, according to pain medicine physicians who have come together to discuss the latest in pain research and treatment at the 24th Annual Meeting of the American Academy of Pain Medicine (AAPM), February 12-16 at the Gaylord Palms in Kissimmee (Orlando), Florida.

17 Feb 2008

Gene therapy for pain

Researchers in the Department of Medicine and Department of Neurosciences at Mount Sinai School of Medicine have discovered that chronic pain can be successfully treated with novel targeted gene therapy.

23 Jan 2008

Minorities less likely to receive pain-relieving opioid drugs in ER

Blacks and Hispanics who go to hospital emergency departments in pain are significantly less likely than whites to get pain-relieving opioid drugs, according to a new study funded by the U.S. Department of Health and Human Services.

7 Jan 2008

Use of opioid medications for pain in ERs on the rise, but racial differences in use still exist

In the last 15 years, use of opioid medications to treat patients with pain-related emergency department visits has improved although white patients were more likely to receive opioids than patients of a different race/ethnicity, according to a study in the January 2 issue of JAMA: The Journal of the American Medical Association.

2 Jan 2008

Blacks, Hispanics less likely to get strong pain drugs in emergency rooms

Despite increases in the overall use of opioid drugs to relieve severe pain, black and Hispanic patients remain significantly less likely than whites to receive these pain-relievers in emergency rooms, according to a new national study.

2 Jan 2008

Pain treatment in the field: Good for soldiers' comfort and better for rebuilding troop strength

Noncombat-related acute and recurrent chronic pain are the leading causes of soldier attrition in modern war, with the return-to-duty rate as low as 2 percent when these soldiers are treated outside the theaters of operation.

18 Dec 2007

Morphine for cancer pain relief

Cancer patients are suffering unnecessarily because they wrongly believe that morphine and other opioids are only used as “comfort for the dying” and as a “last resort” rather than seeing them as legitimate pain killers that can improve their quality of life.

10 Dec 2007