Opioids News and Research

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An opioid is a chemical that works by binding to opioid receptors, which are found principally in the central nervous system and the gastrointestinal tract. The receptors in these two organ systems mediate both the beneficial effects and the side effects of opioids.

FDA approves Relistor for opioid-induced constipation - helps reduce effects of drugs like morphine on bowel function

The U.S. Food and Drug Administration today approved Relistor (methylnaltrexone bromide) to help restore bowel function in patients with late-stage, advanced illness who are receiving opioids on a continuous basis to help alleviate their pain.

24 Apr 2008

Oral methadone dosing for chronic pain: practitioner's guide

Methadone, a strong opioid analgesic, is an effective and economical choice for the management of cancer pain and chronic noncancer pain, both as a first line medication and as a replacement opioid.

14 Mar 2008

Abuse of prescription medications linked to drug abuse among college students

College students who take frequently abused medications without a prescription appear to have a higher risk for drug abuse than those who use such therapies for medical reasons, according to a report in the March issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

4 Mar 2008

FDA approves Aloxi injection for prevention of postoperative nausea and vomiting

Eisai Corporation of North America, its U.S. subsidiary, MGI PHARMA, INC., and Helsinn Healthcare SA today announced that the U.S. Food and Drug Administration (FDA) has approved Aloxi (palonosetron hydrochloride) injection for the prevention of postoperative nausea and vomiting (PONV) for up to 24 hours following surgery.

4 Mar 2008

Minorities less likely to receive pain-relieving opioid drugs in ER

Blacks and Hispanics who go to hospital emergency departments in pain are significantly less likely than whites to get pain-relieving opioid drugs, according to a new study funded by the U.S. Department of Health and Human Services.

7 Jan 2008

Use of opioid medications for pain in ERs on the rise, but racial differences in use still exist

In the last 15 years, use of opioid medications to treat patients with pain-related emergency department visits has improved although white patients were more likely to receive opioids than patients of a different race/ethnicity, according to a study in the January 2 issue of JAMA: The Journal of the American Medical Association.

2 Jan 2008

Blacks, Hispanics less likely to get strong pain drugs in emergency rooms

Despite increases in the overall use of opioid drugs to relieve severe pain, black and Hispanic patients remain significantly less likely than whites to receive these pain-relievers in emergency rooms, according to a new national study.

2 Jan 2008

Pain treatment in the field: Good for soldiers' comfort and better for rebuilding troop strength

Noncombat-related acute and recurrent chronic pain are the leading causes of soldier attrition in modern war, with the return-to-duty rate as low as 2 percent when these soldiers are treated outside the theaters of operation.

18 Dec 2007

Morphine for cancer pain relief

Cancer patients are suffering unnecessarily because they wrongly believe that morphine and other opioids are only used as “comfort for the dying” and as a “last resort” rather than seeing them as legitimate pain killers that can improve their quality of life.

10 Dec 2007

New non-addictive pain-killers

Two University of Adelaide pharmacologists working with one the world's leading neuroscientists have helped pave the way for the development of new pain-killing drugs that are not addictive.

20 Nov 2007

Anesthesia pouch allows children to go home sooner after surgery

Children recovering from orthopaedic surgery feel less pain and leave the hospital sooner when they go home with a small pouch that delivers local anesthetic agents and blocks pain transmission from surgical sites.

5 Nov 2007

Medicaid pays for one-third of drug abuse hospitalizations

Medicaid paid for more than one-third of the 1.3 million hospital stays related to prescription or illegal drug abuse in 2005, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

2 Nov 2007

Acupuncture before and during surgery reduces the need for powerful painkillers

A new study has found that using acupuncture before and during surgery significantly reduces the level of pain and level of painkillers needed by patients following surgery.

17 Oct 2007

Nicotine patch for prostate surgery relief?

The use of a nicotine patch - successfully used to help many smokers decrease their dependency on nicotine - was shown to reduce pain in men after prostate removal surgery in a new anesthesiology study.

15 Oct 2007

How does the opioid system work?

The opioid system controls pain, reward and addictive behaviors. Opioids exert their pharmacological actions through three opioid receptors, mu, delta and kappa whose genes have been cloned (Oprm, Oprd1 and Oprk1, respectively).

15 Oct 2007

New guidelines for treating low-back pain

The American College of Physicians (ACP) and the American Pain Society (APS) today released joint guidelines on diagnosing and treating low back pain.

2 Oct 2007

Research explains why opioids are thought to be ineffective in people with fibromyalgia

People who have the common chronic pain condition fibromyalgia often report that they don't respond to the types of medication that relieve other people's pain.

27 Sep 2007

Warning about dangerous potential of pain drug Fentora

The Food and Drug Administration (FDA) in the United States has warned doctors about the dangers of a drug used to treat pain in cancer sufferers.

26 Sep 2007

Opioid-based pain medications may cause sleep apnea

Opioid-based pain medications may cause sleep apnea, according to an article in the September issue of Pain Medicine, the journal of the American Academy of Pain Medicine.

10 Sep 2007

Watson Pharmaceuticals receives FDA approval for generic Duragesic

Watson Pharmaceuticals, Inc. announced today that it has received final approval from the United States (U.S.) Food and Drug Administration (FDA) on its Abbreviated New Drug Application (ANDA) for fentanyl transdermal system in the 25, 50, 75 & 100 mcg/hour strengths.

21 Aug 2007