Optical Imaging News and Research

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High-resolution still images alongside high-speed video footage for detailed scientific imaging

Scientists funded by the Biotechnology and Biological Sciences Research Council and the British Heart Foundation at the University of Oxford have developed a revolutionary way of capturing a high-resolution still image alongside very high-speed video - a new technology that is attractive for science, industry and consumer sectors alike.

15 Feb 2010

Noninvasive optical imaging probes to determine amount and type of cell death in tumors

For quite some time, the "Holy Grail" in medical imaging has been the development of an effective method to image cell death as a means to intervene early in diseases and rapidly determine the effectiveness of treatments. A new paper by researchers at the University of Notre Dame and the Washington University School of Medicine describes important progress in using a synthetic probe to target dead and dying cells in mammary and prostate tumors in living animals.

30 Jan 2010

Top pharmaceutical companies select CRi solutions for drug research and development

Growth of OMI equipment sales to reach $400M in 2014

In vivo optical molecular imaging (OMI) is poised to move into clinical use as one of the key tools in personalized medicine, complementing more established imaging tools such as CT and MRI. Growth of equipment sales is on track to reach $400 million in 2014 and nearly $1 billion by the end of the decade.

21 Jan 2010

Portugal life scientist awarded ERC's Advanced Investigator Grant

Zachary Mainen, coordinator of the Champalimaud Foundation Neuroscience Programme at the IGC, has become one of the most recent winners of the prestigious and highly competitive European Research Council grants, to the value of 2.3 million euro, for a period of five years. This grant, which recognises Mainen's contribution to the Neuroscience field, will be used to elucidate the biological role of the neurotransmitter serotonin.

18 Jan 2010

IGC scientist wins ERC grant for neuroscience research

18 Jan 2010

Axsun Technologies reports successful testing of novel OCT imaging integrated light source architecture

Axsun Technologies, Inc., a wholly-owned subsidiary of Volcano Corporation, today announced the initial development and successful testing of a novel integrated light source architecture for OCT imaging. Axsun believes this proprietary optical engine design raises the bar on imaging speed and overcomes fundamental limitations of laser-based designs for swept source OCT light sources.

4 Dec 2009

Study suggests brain can integrate new information without jeopardizing established memories

Our ability to learn new information and adapt to changes in our daily environment, as well as to retain lifelong memories, appears to lie in the minute junctions where nerve cells communicate, according to a new study by NYU Langone Medicine Center researchers. The study is published online this week in the journal Nature.

4 Dec 2009

CRi announces study results of imaging and analysis platform for drug and molecular diagnostic development

Cambridge Research & Instrumentation, Inc. (CRi), a leader in biomedical imaging, today announced the results of a study demonstrating for the first time the capability to detect and automatically measure key activity indicators of cancer cell signal transduction pathways in intact tissue.

2 Dec 2009

Caliper Life Sciences unveils XenoLight Rediject reagents series at WMIC

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery and life sciences research, today introduced a series of XenoLight Rediject reagents at the World Molecular Imaging Congress (WMIC) in Montreal, Canada. Rediject D-Luciferin Ultra is the latest in an expanding range of XenoLight reagents for Caliper's IVIS optical imaging systems.

25 Sep 2009

Twinkling nanostars improve optical imaging of tumors

Researchers at Purdue University have created magnetically responsive gold nanostars that may offer a new approach to biomedical imaging. The nanostars gyrate when exposed to a rotating magnetic field and can scatter light to produce a pulsating or "twinkling" effect. This twinkling allows them to stand out more clearly from noisy backgrounds such as those found in biological tissue. Alexander Wei, Ph.D., and Kenneth Ritchie, Ph.D., M.Sc., led the team that created the new gyromagnetic imaging method. The work appears in a paper published in the Journal of the American Chemical Society.

23 Sep 2009

IVIS Lumina XR in vivo imaging system from Caliper Life Sciences

Caliper Life Sciences, Inc., a leading provider of tools and services for drug discovery and life sciences research, today introduced the IVIS Lumina XR in vivo imaging system, the latest addition to the IVIS product family.

14 Sep 2009

Specific targeting of brain tumors with an optical/magnetic resonance imaging nanoprobe across the blood-brain barrier

Earlier this year, researchers at the University of Washington reported that they had developed a toxin-nanoparticle combination that inhibits brain cancer invasion when added to tumor cells growing in culture.

7 Sep 2009

SoftScan clinical results from a breast cancer treatment monitoring study to be presented at IEEE International Conference

ART Advanced Research Technologies Inc. (ART) (TSX:ARA), a Canadian medical device company and a leader in optical molecular imaging products for the healthcare and pharmaceutical industries, is pleased to announce that Dr. Gregory Czarnota, MD, PhD, Radiation Oncologist at Odette Cancer Centre, Sunnybrook Health Sciences Centre, will be presenting SoftScan® clinical results from a breast cancer treatment monitoring study, at the IEEE Engineering in Medicine and Biology Society 31st Annual International Conference in Minneapolis, Minn.

5 Sep 2009

BF STEM tomography allows to visualize fine details of cell structure

Scientists in the National Institute of Biomedical Imaging and Bioengineering (NIBIB) Laboratory of Bioengineering and Physical Science have developed a new technique that allows researchers to visualize fine details of cell structure three-dimensionally in thick sections, thus providing greater insight into how cells are organized and how they function. The work is described in a report published online this week in Nature Methods.

4 Sep 2009

Two-photon microscopy technique tracks calcium levels in mice neurons

For over a century, scientists have been using electrical stimulation to explore and treat the human brain. The technique has helped identify regions responsible for specific neural functions-for instance, the motor cortex and pleasure center-and has been used to treat a variety of conditions from Parkinson's disease to depression.

27 Aug 2009

Scientists illuminate brain tumors with fluorescent nanoparticles

Brain cancer is among the deadliest of cancers. It's also one of the hardest to treat. Imaging results are often imprecise because brain cancers are extremely invasive. Surgeons must saw through the skull and safely remove as much of the tumor as they can. Then doctors use radiation or chemotherapy to destroy cancerous cells in the surrounding tissue.

3 Aug 2009

A new prostate cancer "homing device" for drug delivery

A new prostate cancer "homing device" could improve detection and allow for the first targeted treatment of the disease. A team of Purdue University researchers has synthesized a molecule that finds and penetrates prostate cancer cells and has created imaging agents and therapeutic drugs that can link to the molecule and be carried with it as cargo.

6 Jul 2009

Early detection of pancreatic cancer closer thanks to multifunctional nanoparticles

Pancreatic cancer has a devastatingly low survival rate (less than 5 percent after 5 years) because it is usually diagnosed at an advanced stage. The initial symptoms, such as pain, jaundice, or weight loss, often do not allow the disease to be caught early enough for surgery and chemotherapy to be effective.

28 Jun 2009

Taxol-carrying nanoparticles

Nanoparticles specially engineered by University of Central Florida Assistant Professor J. Manuel Perez and his colleagues could someday target and destroy tumors, sparing patients from toxic, whole-body chemotherapies.

17 Jun 2009