Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

“Fail Fast, But More Confidently”: Developing Organoids for Drug Development and Discovery

Richard Eglen discusses the use of organoids in drug discovery, including the screening of candidate compounds for efficacy, toxicity, and pharmacokinetics.

From Corning Life Sciences 13 Mar 2019

Creating increasingly complex brain organoids

Scientists improved the initial steps of a standard protocol and produced organoids displaying regionalized brain structures, including retinal pigmented cells. The announcement was published today in BMC Developmental Biology by the D'Or Institute for Research and Education's team.

8 Mar 2019

Lonza expands portfolio with addition of new 'Verified for Spheroids Human Hepatocytes'

Lonza has further expanded its hepatocytes portfolio characterization with the addition of Verified for Spheroids Human Hepatocytes, which are pre-screened for their ability to promote rapid spheroid formation in cell culture.

From Lonza 5 Mar 2019

Scientists successfully create kidney organoids from urine cells

Scientists from Utrecht University, University Medical Center Utrecht and Hubrecht Institute have successfully created kidney organoids from urine cells.

5 Mar 2019

New clues to triggers of gut inflammation uncovered

New detail about what happens when a key cellular process is impaired in cells that are vital for a healthy gut have been uncovered by a wide-ranging analysis.

28 Feb 2019

MD&M West 2019: Medical Devices, 3D Printing and Staying Compliant

Between February 5 - 7 2019, the Anaheim Convention Center in Southern California hosted the annual MD&M West medical manufacturing conference.

27 Feb 2019

Miniature tumor organoids could help guide treatment decisions for people with rare cancers

UCLA scientists have developed a new method to quickly screen hundreds of drugs in order to identify treatments that can target specific tumors.

26 Feb 2019

Researchers develop powerful new approach to improve maturation of miniature kidneys

In recent years, researchers have created mini-organs known as organoids in the culture dish that contain many of the cell types and complex microarchitectures found in human organs, such as the kidney, liver, intestine, and even the brain.

13 Feb 2019

New autism mouse model shows how epigenetic regulation impacts downstream gene

The causes of autism spectrum disorder are diverse and to some extent, unknown. But without doubt, they are complex, layered and deeply nuanced.

31 Jan 2019

Corning Life Sciences to highlight advanced 3D cell culture technologies and tools at SLAS 2019

Corning Incorporated will showcase advanced 3D cell culture technologies and workflow solutions, and including those for high throughput screening and ADME/toxicology at SLAS 2019.

From Corning Life Sciences 30 Jan 2019

Researchers develop new tool that images blood flow through tiny capillaries

More than 40 billion capillaries -- tiny, hair-like blood vessels -- are tasked with carrying oxygen and nutrients to the far reaches of the human body.

28 Jan 2019

Cancer Research UK announces £60 million funding to tackle global cancer challenges

Cancer Research UK announced today that it is funding three major new international research initiatives on the microbiome, chronic inflammation and why some cancers are specific to certain tissues and not others.

23 Jan 2019

Top institutions in the U.S. win Cancer Research UK's Grand Challenge competition

The U.S. will lead three new global research projects, tackling some of the biggest challenges in cancer research, it was announced today by Cancer Research UK.

23 Jan 2019

UCLA researchers demonstrate new technique to develop cancer-fighting T cells

A study by UCLA researchers is the first to demonstrate a technique for coaxing pluripotent stem cells -- which can give rise to every cell type in the body and which can be grown indefinitely in the lab -- into becoming mature T cells capable of killing tumor cells.

18 Jan 2019

Blood vessels can now be created perfectly in a petri dish

Researchers have now successfully created perfect blood vessels in the labs and this may be a huge step in benefitting people with diabetes and other conditions. The report of the procedure appears in a study titled, “Human blood vessel organoids as a model of diabetic vasculopathy,” published in the latest issue of the journal Nature.

17 Jan 2019

New project finds how endocrine disruptors interfere with thyroid functions

Endocrine disruptors are a class of chemicals used to produce materials commonly found in everyday life, such as some plastics, tin cans, electrical and household appliances, cosmetics, pesticides, etc.

17 Jan 2019

Researchers cultivate vascular organoids that perfectly mimic human blood vessels

For the first time, researchers have successfully cultivated “vascular organoids” in a petri dish that perfectly mimic real human blood vessels.

16 Jan 2019

LifeTime receives fund to develop a plan to embed its vision for healthier future

Our body's cells are constantly changing. But which of these changes are healthy developments and which lead to serious diseases? This is what LifeTime, a new transnational and interdisciplinary initiative of leading European researchers, aims to discover.

16 Jan 2019

University of Cincinnati professor awarded $1.6 million NIAID grant to study Hamburger E. coli

Alison Weiss, PhD, professor in the Department of Molecular Genetics, Biochemistry and Microbiology in UC College of Medicine, has been awarded a four-year grant of $1.6 million from the National Institute of Allergy and Infectious Diseases to study Shiga toxin producing Escherichia coli 0157:H7, also sometimes referred to as Hamburger E. coli.

9 Jan 2019

Olympus and USC announce new partnership to advance cancer research

The University of Southern California and Olympus have announced their first-ever co-development partnership with the goal of advancing multiscale research into cancer prevention, diagnosis, and treatment through precision medicine.

From Evident Corporation - Life Sciences 9 Jan 2019