Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Organoids derived from cancer cells can reduce the need for trial and error in identifying effective treatments

Researchers created organoids from cancer cells to reduce the need for trial and error in identifying effective cancer treatments in one of many cancer studies scheduled for presentation this week at Digestive Disease Week (DDW) 2023.

8 May 2023

Organoid models provide new scientific insights into a rare childhood liver cancer

Scientists of the Princess Máxima Center for pediatric oncology and Hubrecht Institute in the Netherlands have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer

3 May 2023

Mechanism to protect the liver from destruction in case of obesity revealed

Scientists from the Immanuel Kant Baltic Federal University found out that blocking of receptor gp130 on the surface of liver cells helps to protect this organ from destruction in case of obesity.

27 Apr 2023

Researchers explore the role of a genetic process in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer. It's also one of the deadliest. More than 90% of PDAC patients die within five years of diagnosis.

26 Apr 2023

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Researchers explored increasing replicative fitness of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

20 Apr 2023

New approach identifies significant molecular changes linked to pediatric bipolar disorder

It's extremely difficult to study the biological basis of psychiatric disorders, in part because researchers can't easily collect brain cells from living people to study in the laboratory. Now, University of Utah Health scientists have developed a way around that.

12 Apr 2023

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Developing and testing new treatments or vaccines for humans almost always requires animal trials, but these experiments can sometimes take years to complete and can raise ethical concerns about the animals' treatment.

12 Apr 2023

Bioprinting combined with AI allows to obtain high-quality homogenized in vitro models

In the process of organoid manufacturing, bioprinting technology can not only facilitate the creation and maintenance of complex biological 3D shapes and structures, but also allow for standardization and quality control during production.

11 Apr 2023

A creative new approach to make vaccine against norovirus

Every year, norovirus causes hundreds of millions of cases of food poisoning -; and the deaths of at least 50,000 children -; yet there exists no real way to control it.

11 Apr 2023

Ingenious device enables construction of complex 3D organoids in a simpler way

A team led by Masaya Hagiwara of RIKEN national science institute in Japan has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques.

7 Apr 2023

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Researchers assessed the extent of SARS-CoV-2 Omicron VOC BA.5 sub-VOC infection-associated brain infection and death.

5 Apr 2023

Using brain organoids to test gene therapies for a rare disease in children

Brain tissue grown in a laboratory by University of Queensland researchers will be used to test a treatment for a rare disease in children and help unlock therapies for a range of neurological disorders.

5 Apr 2023

Researchers develop a method for making “mini-heart” using pluripotent stem cells

A team at the Technical University of Munich has induced stem cells to emulate the development of the human heart.

5 Apr 2023

Innovative approach to customize treatments for colorectal cancer

How to determine the most effective treatment for colon cancer? The response to chemotherapy varies greatly from one patient to another.

4 Apr 2023

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy and diagnostic applications, today announced the launch of its new spinning disk confocal microscope system, CICERO.

From CrestOptics 3 Apr 2023

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

A National Institutes of Health team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

29 Mar 2023

Understanding how to better prescribe probiotics based on our individual microbiome profiles

Bacteria have thousands of genes and functions that we, the human host, do not have. For instance, bacteria can help us digest fiber, provide support to our immune systems, and absorb important nutrients. But reaping the benefits of "good bacteria" is easier said than done.

28 Mar 2023

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

A new UCLA-led study suggests that advanced genome editing technology could be used as a one-time treatment for the rare and deadly genetic disease CD3 delta severe combined immunodeficiency.

21 Mar 2023

Embryonic stem cells used to recreate thyroid cancer histotypes

A recent Nature Communications study revealed the recapitulating capacity of human embryonic stem cells (hESCs) to elucidate the cellular hierarchy of the thyroid gland. Furthermore, these cells possessed the capacity to reproduce the oncogenic process using the CRISPR-based genetic editing method.

14 Mar 2023

ACE2: its diverse functions, relationship with SARS-CoV-2, and the implications for COVID-19 disease sequelae

Researchers assessed the role of ACE2 in the COVID-19 pandemic.

9 Mar 2023

Organoids News and Research

Further Reading

Organoids derived from cancer cells can reduce the need for trial and error in identifying effective treatments

Organoid models provide new scientific insights into a rare childhood liver cancer

Mechanism to protect the liver from destruction in case of obesity revealed

Researchers explore the role of a genetic process in pancreatic cancer

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

New approach identifies significant molecular changes linked to pediatric bipolar disorder

New organoid platform could make vaccine screening quicker and greatly reduce animal testing

Bioprinting combined with AI allows to obtain high-quality homogenized in vitro models

A creative new approach to make vaccine against norovirus

Ingenious device enables construction of complex 3D organoids in a simpler way

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Using brain organoids to test gene therapies for a rare disease in children

Researchers develop a method for making “mini-heart” using pluripotent stem cells

Innovative approach to customize treatments for colorectal cancer

CrestOptics launches CICERO system to provide all-in-one solution for widefield and spinning disk confocal microscopy

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

Understanding how to better prescribe probiotics based on our individual microbiome profiles

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

Embryonic stem cells used to recreate thyroid cancer histotypes

ACE2: its diverse functions, relationship with SARS-CoV-2, and the implications for COVID-19 disease sequelae

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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