Orthostatic Hypotension News and Research

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Dizziness could be an early sign of dementia finds study

A new study has found that people who feel dizzy when they stand up from lying down or sitting positions, are more at risk of developing dementia or stroke. The study was published in the latest issue of the journal Neurology.

25 Jul 2018

Aggressive lowering of blood pressure reduces MCI risk, study shows

Significant reductions in the risk of mild cognitive impairment (MCI), and the combination of MCI and dementia, have been shown for the first time through aggressive lowering of systolic blood pressure in new research results from the federally-funded SPRINT MIND Study reported at the Alzheimer's Association International Conference 2018 in Chicago.

25 Jul 2018

Adults with orthostatic hypotension may have undiagnosed cardiovascular disease

Orthostatic hypotension - a rapid drop in blood pressure upon standing up from a sitting or lying down position - is a frequently encountered clinical sign among patients.

3 Jul 2018

Simple bedside test may help doctors diagnose certain degenerative brain diseases

A simple bedside test that matches a change in heart rate with a drop in blood pressure after a patient stands may help doctors diagnose certain degenerative brain diseases.

28 Mar 2018

Bowel care ranks top concern for individuals with spinal cord injury, study shows

Cardiovascular physiology researcher Victoria Claydon's latest study, published in the Journal of Neurotrauma, focuses on the results of her multi-national study, which surveyed almost 300 participants with spinal cord injuries at or above the mid-thoracic level (middle of the chest ).

9 Mar 2018

Experimental treatment improves invisible symptoms of a man with spinal cord injury

An experimental treatment that sends electrical currents through the spinal cord has improved "invisible" yet debilitating side effects for a B.C. man with a spinal cord injury.

19 Feb 2018

Study recommends revision of current guidelines for assessing orthostatic hypotension

A new study led by Johns Hopkins researchers suggests that testing for the presence of orthostatic hypotension, a form of low blood pressure, be performed within one minute of standing after a person has been lying down.

31 Jul 2017

Diabetes leads to increase in autonomic and small fiber neuropathy

Autonomic and small fiber neuropathy used to be considered rare conditions. But with approximately 30 million Americans affected by diabetes – one of the main underlying causes for these diseases – it's an emerging problem.

13 Jul 2017

Temporary blood pressure drops in middle age may increase risk of dementia in later years

Middle-aged people who experience temporary blood pressure drops that often cause dizziness upon standing up may be at an increased risk of developing cognitive decline and dementia 20 years later, new Johns Hopkins Bloomberg School of Public Health research suggests.

10 Mar 2017

Upright posture in patients with Parkinson's disease exacerbates cognitive deficits, study shows

In a new study published online today in the journal Neurology, a research team led by neurologists at Beth Israel Deaconess Medical Center and neuropsychologists at Boston University has shown that when patients with Parkinson's disease experience a drop in blood pressure upon standing up - a condition known as orthostatic hypotension (OH) - they exhibit significant cognitive deficits.

30 Nov 2016

$New review looks at complexity of fracture epidemiology in diabetes$

New review looks at complexity of fracture epidemiology in diabetes

Due to the ageing of populations as well as increasing obesity and adverse lifestyle factors, type 2 diabetes (T2D) is reaching epidemic proportions in many parts of the world.

17 Oct 2016

Promising phase II results for ozanimod in MS

The selective sphingosine 1-phosphate receptor inhibitor ozanimod significantly reduces lesion activity in patients with relapsing-remitting multiple sclerosis, shows a phase II study published in The Lancet Neurology.

17 Feb 2016

Feeling dizzy after standing up may signal serious conditions, increased risk of death

People who get dizzy several minutes after standing up may be at risk of more serious conditions and even an increased risk of death, according to new research published in the September 23, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

24 Sep 2015

Nonmotor features may predict PD progression

The presence of mild cognitive impairment, orthostatic hypotension, and rapid eye movement sleep behaviour disorder may identify a subset of Parkinson’s disease patients with a poor prognosis, research suggests.

19 Jun 2015

FDA approves RYTARY for Parkinson's disease treatment

Impax Pharmaceuticals, a division of Impax Laboratories, Inc., today announced that the U.S. Food and Drug Administration approved RYTARY, an extended-release oral capsule formulation of carbidopa-levodopa, for the treatment of Parkinson's disease, post-encephalitic parkinsonism, and parkinsonism that may follow carbon monoxide intoxication and / or manganese intoxication.

8 Jan 2015

Many pediatric chest X-rays unnecessary, offer no clinical benefit

Researchers at Mayo Clinic found that some children are receiving chest X-rays that may be unnecessary and offer no clinical benefit to the patient, according to a study presented today at the annual meeting of the Radiological Society of North America.

3 Dec 2014

Nonmotor predictors of Parkinson’s dementia revealed

Researchers have identified nonmotor and nondopaminergic motor features that predict incident dementia in patients with Parkinson’s disease.

22 Oct 2014

Study of astronauts show heart becomes more spherical when exposed to microgravity in space

New findings from a study of 12 astronauts show the heart becomes more spherical when exposed to long periods of microgravity in space, a change that could lead to cardiac problems, according to research to be presented at the American College of Cardiology's 63rd Annual Scientific Session.

31 Mar 2014

FDA grants accelerated approval to NORTHERA (droxidopa) for patients with symptomatic NOH

Chelsea Therapeutics International, Ltd. today announced that the U.S. Food and Drug Administration granted accelerated approval of NORTHERA (droxidopa) for the treatment of symptomatic neurogenic orthostatic hypotension (NOH). NORTHERA is the first and only therapy approved by the FDA which demonstrates symptomatic benefit in patients with NOH.

18 Feb 2014

Sleep disorder linked to poor nonmotor status in Parkinson’s disease

The presence of rapid eye movement sleep behavior disorder is associated with more severe nonmotor symptoms in patients with early-stage Parkinson’s disease, a study shows.

8 Jan 2014