Osteoclast News and Research

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Intermittent fasting's impact on bone health

Although several studies have indicated intermittent fasting (IF) promotes weight loss and improves metabolic health, its effect on bone health is unclear. Recently, scientists reviewed existing literature and summarized the effect of varied forms of IF, such as the 5:2 diet, alternate day fasting (ADF), and time-restricted eating/feeding (TRE/TRF), on bone health. This review is available in the British Journal of Nutrition.

7 Mar 2023

Study opens new therapeutic avenues for treatment of rheumatoid arthritis

A research team, led by Professor Sung Ho Park in the Department of Biological Sciences at UNIST announced the results of a study on osteoblasts that damage joint bones in patients with rheumatoid arthritis.

31 Jan 2023

Unique technology uses ultrasound-responsive nanobubbles for treating osteoporosis

University of Central Florida researchers have created unique technology for treating osteoporosis that uses nanobubbles to deliver treatment to targeted areas of a person's body.

6 Dec 2022

Treg transplantation improves bone remodeling, study says

The building blocks of a structure consist of load-bearing elements that rarely change despite renovations or repairs. They remain intact and consistent over time, but in the human body, our building blocks do just the opposite.

13 Sep 2022

$Elevated blood levels of certain chemokine linked with higher hip fracture risk in men$

Elevated blood levels of certain chemokine linked with higher hip fracture risk in men

Bone health requires a balanced activity of various bone cell types including bone-forming osteoblasts and bone-resorbing osteoclasts.

17 Aug 2022

$Chemokines likely to be associated with the risk of osteoporotic hip fracture in older men$

Chemokines likely to be associated with the risk of osteoporotic hip fracture in older men

Bone health requires a balanced activity of various bone cell types including bone-forming osteoblasts and bone-resorbing osteoclasts. Osteoporosis occurs when osteoclasts dominate without adequate bone formation to compensate. In new research published in the Journal of Bone and Mineral Research, elevated blood levels of a certain chemokine, or small signaling protein, that promotes osteoclast formation were linked with a higher risk of hip fracture in men.

17 Aug 2022

Bisphosphonates appear to improve COVID-19 exposure outcomes

A new retrospective study examines the effect of bisphosphonates on COVID-19 outcomes.

27 Jun 2022

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

Researchers profiled the binding sites of the entire SARS-CoV-2 spike protein sequence.

26 May 2022

Researchers discover new mechanisms for bone loss in gum disease

Tokyo University of Agriculture and Technology researchers reported on a new discovery regarding the mechanisms for bone loss in gum disease (periodontitis). They found that double stranded RNA molecules can activate the immune system response that leads to deterioration of bone.

8 Apr 2022

Scientists reveal molecular mechanisms behind bone loss caused by chronic liver injury

A research team led by Prof. Chen Di from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences along with other collaborators have revealed the molecular mechanisms behind bone loss caused by chronic liver injury.

1 Mar 2022

Osteoblast-derived vesicles regulate the switch from bone formation to resorption via a miRNA-mediated mechanism

Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown.

25 Feb 2022

Study shows link between oral microbiome and naturally occurring alveolar bone loss

It is becoming increasingly clear that the human microbiome – the collection of bacteria, viruses and fungi that live on and within us – significantly contributes to our health.

17 Feb 2022

Study improves understanding of the link between obesity and gum disease

Chronic inflammation caused by obesity may trigger the development of cells that break down bone tissue, including the bone that holds teeth in place, according to new University at Buffalo research that sought to improve understanding of the connection between obesity and gum disease.

12 Nov 2021

New discovery suggests potential treatment target for osteoporosis and rheumatoid arthritis

A new discovery about osteoporosis suggests a potential treatment target for that brittle-bone disease and for bone loss from rheumatoid arthritis.

14 Oct 2021

Molecular underpinning of chronic bone infection in patients with mycobacterial disease revealed

About a quarter of the world's population is infected with tuberculosis bacteria, according to the World Health Organization, but only about 5 to 10% of those infected will develop symptoms. These pathogens are mycobacteria, which are everywhere, including in chlorine-treated tap water.

8 Sep 2021

Osteoclast News and Research

Intermittent fasting's impact on bone health

Study opens new therapeutic avenues for treatment of rheumatoid arthritis

Unique technology uses ultrasound-responsive nanobubbles for treating osteoporosis

Treg transplantation improves bone remodeling, study says

Elevated blood levels of certain chemokine linked with higher hip fracture risk in men

Chemokines likely to be associated with the risk of osteoporotic hip fracture in older men

Bisphosphonates appear to improve COVID-19 exposure outcomes

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

Researchers discover new mechanisms for bone loss in gum disease

Scientists reveal molecular mechanisms behind bone loss caused by chronic liver injury

Osteoblast-derived vesicles regulate the switch from bone formation to resorption via a miRNA-mediated mechanism

Study shows link between oral microbiome and naturally occurring alveolar bone loss

Study improves understanding of the link between obesity and gum disease

New discovery suggests potential treatment target for osteoporosis and rheumatoid arthritis

Molecular underpinning of chronic bone infection in patients with mycobacterial disease revealed

SARS-CoV-2 can alter bone marrow macrophage (BMM)-to-osteoclast differentiation, study finds

Researchers discover potential cellular target for eliminating bone breakdown in osteoporosis

Heat and gut microbiota promote stronger bones

Researchers develop new strategies to treat osteoporosis

Researchers develop a novel strategy to fight osteoporosis

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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