Ovaries News and Research

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Human iPSC-derived fallopian tube organoids reveal the origins of common ovarian cancer

Stem cell scientists have revealed the origins of a common ovarian cancer by modeling fallopian tube tissues, allowing them to characterize how a genetic mutation puts women at high risk for this cancer.

29 Dec 2021

Study sheds light on how the immune system behaves during pregnancy

Pregnancy is a challenge for the mother's immune system from the outset. Half of the genes in the fetus are foreign to her body.

29 Dec 2021

Bilateral salpingo-oophorectomy may have risks for younger women, but safe for post-menopausal patients

A study of over 200,500 women who had a hysterectomy for non-cancerous reasons found an increased risk of death in women under 50 years of age when the ovaries and fallopian tubes were also removed during the surgery. The same association was not found in women over 50.

9 Dec 2021

Hypothyroidism and thyroid autoimmunity can negatively affect a woman's ovarian reserve

Thyroid hormones are important for ovarian health and fertility, but the effects of low thyroid hormone levels (hypothyroidism) and thyroid autoimmune diseases on the functioning of a woman's ovaries are not fully understood.

8 Dec 2021

Cancer registry offers a better understanding of ovarian granulosa cell tumors

Examination of Japanese cases of gynecological cancer offers a better understanding of the profile of a rare ovarian tumor and could change treatment guidelines.

4 Dec 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

Researchers identify gene expression involved in cancer progression and chemotherapy resistance

Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy.

11 Nov 2021

Pathway preferential estrogens may be a safer alternative to hormone replacement therapy, study shows

Postmenopausal women have increased risk of non-alcoholic fatty liver disease due to loss of estrogen from metabolic changes. A high-fat diet further exacerbates the disease, which can progress to cirrhosis and liver failure.

29 Oct 2021

New discovery could help better understand how cells migrate during early development

Cells can control their ability to move through the body by using a protein called fascin to control the stiffness of neighboring cells, suggests a study published today in eLife.

26 Oct 2021

Researchers uncover the role of estrogen in exercise

Experts in sex as a biological variable are uncovering the role of estrogen in exercise. The researchers will present their findings virtually at the American Physiological Society's (APS) New Trends in Sex and Gender Medicine conference.

19 Oct 2021

Contraceptive pill can reduce the risk of type 2 diabetes in women with PCOS, study reveals

A study led by the University of Birmingham has revealed for the first time that the contraceptive pill can reduce the risk of type 2 diabetes by over a quarter in women with polycystic ovary syndrome (PCOS).

15 Oct 2021

Researchers identify neurons and signaling pathways that make sexually receptive females more active

Scientists have known for a century that female animals become more active just as they are about to ovulate, a behavior that evolved to enhance their chances of mating when they are fertile.

15 Oct 2021

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Researchers at Johns Hopkins Medicine have found that a drug first developed to treat Alzheimer's disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function — without changes in food intake or daily activity.

7 Oct 2021

Young people with cancer face inequalities in fertility preservation services across the UK

Young people who survive cancer are at risk of missing out on the chance to have children in the future, due to inequalities in fertility preservation services across the UK, new research has found.

22 Sep 2021

Liquid biopsies could help identify, track bladder cancer and peripheral nerve tumors

Liquid biopsies detect tumor DNA in blood or urine samples. Two studies led by Washington University School of Medicine in St. Louis describe the potential of liquid biopsies to identify and track tumor growth in two very different cancers: bladder cancer and peripheral nerve tumors.

31 Aug 2021

Can molecular mimicry impact fertility in female COVID-19 patients?

There exists a possibility that COVID-19 can also affect the reproductive function in the body, which can lead to infertility in infected patients. A study published in the American Journal of Reproductive Immunology explored the impact of SARS-CoV-2 infection on reproductive functions and fertility.

30 Aug 2021

Researchers discover how PARP inhibitors selectively kill BRCA-mutant cancer cells

A team of Massachusetts General Hospital researchers has discovered how an important class of anti-cancer drugs called PARP inhibitors works, a finding that could help improve treatment and prolong survival for patients with breast cancer and other malignancies.

12 Aug 2021

Microbe transmitted between mosquitoes could be key to controlling malaria

A microbe that is transmitted between male and female mosquitoes but can also block reproduction could be key to controlling malaria by targeting its release into mosquito populations, a study says.

10 Aug 2021

Knowledge and support from primary care services can improve women's health during menopause

More knowledge and individual support from primary care services can alleviate women's menopausal problems, a University of Gothenburg thesis shows.

21 Jul 2021

Study finds higher risk of pre-eclampsia, hypertension in pregnancies derived from frozen embryos

A large cohort study drawn from the national IVF registry of France, which included almost 70,000 pregnancies delivered after 22 weeks gestation between 2013 and 2018, has found a higher risk of pre-eclampsia and hypertension in pregnancies derived from frozen-thawed embryos.

30 Jun 2021