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New cell therapy offers effective treatment for patients with T-cell acute lymphoblastic leukemia

A new cell therapy, targeting CD7 on leukaemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukaemia (T-ALL) who have exhausted all standard treatment options.

7 Oct 2024

Simple intervention can prevent lifelong disability in premature babies

Giving women at risk of premature birth a simple magnesium sulphate infusion (or 'drip') can prevent their babies from developing cerebral palsy, a recent Cochrane review has confirmed. The drug itself costs approximately £5 (~$6.50) per dose in England, and requires hospital admission with experienced staff to administer the drug safely to the mother.

24 Sep 2024

ANNs can identify lung disease in preterm infants by analyzing sleep breathing patterns

Artificial Neural Networks (ANNs) can be trained to detect lung disease in premature babies by analyzing their breathing patterns while they sleep, according to research presented at the European Respiratory Society (ERS) Congress in Vienna, Austria.

9 Sep 2024

Young people with chronic pain more likely to have clinical anxiety or depression

Young people with chronic pain are three times more likely than their peers to also have clinical anxiety or depression, a new review has found.

9 Sep 2024

ChatGPT outperforms trainee doctors in respiratory disease assessments

The chatbot ChatGPT performed better than trainee doctors in assessing complex cases of respiratory disease in areas such as cystic fibrosis, asthma and chest infections in a study presented at the European Respiratory Society (ERS) Congress in Vienna, Austria.

9 Sep 2024

Exclusive breastfeeding aids postpartum weight loss

A KK Women's and Children's Hospital (KKH) study[1] on breastfeeding practices revealed that among the women who exclusively breastfed, those with high body mass index[2] (BMI) before pregnancy lost more weight than women with a healthy BMI pre-pregnancy.

27 Aug 2024

World's first rapid TBI blood test debuts at Orlando Health

Orlando Health Orlando Regional Medical Center (ORMC) is the first hospital in the world to use a new, groundbreaking blood test to help assess patients with suspected mild traumatic brain injuries (TBIs), or concussions.

13 Aug 2024

A close collaboration to help children suffering from cancer

The close collaboration between the Paul Scherrer Institute PSI and the University Children's Hospital Zurich for the benefit of children suffering from cancer began 20 years ago.

8 Jul 2024

Baby boys more likely to achieve HIV cure or remission after in-utero infection

Baby girls are more likely to acquire HIV from their mothers during pregnancy or childbirth than infant boys, who are conversely more likely to achieve cure or remission, researchers say in a new study that sheds light on the gender differences in immune systems.

5 Jul 2024

Study unveils crucial insights into how COVID-19 vaccines mitigate severe illness

A landmark study by scientists at the University of Oxford, has unveiled crucial insights into the way that COVID-19 vaccines mitigate severe illness in those who have been vaccinated.

8 May 2024

Real-world data validates gene therapy for spinal muscular atrophy

Findings from a new study in the Journal of Neuromuscular Diseases, published by IOS Press, demonstrate the effectiveness of disease-modifying treatments (DMTs) in infants with spinal muscular atrophy (SMA).

15 Apr 2024

Cystic fibrosis drug found to be safe and effective in newborns

A Cystic Fibrosis drug targeting the basic defect that causes the condition has been shown to be safe and effective in newborns aged four weeks and above, new research involving RCSI University of Medicine and Health Sciences and Children's Health Ireland has found.

12 Apr 2024

Oxford University and Brazil partner to advance malaria vaccine development

Professor Sue Ann Costa Clemens CBE, Chair of Global Health at the Department of Paediatrics and Head of Oxford Latam Research Group - a collaboration between Oxford and Brazil, aimed at strengthening our commitment to global health - met with His Excellency Antonio Patriota, Brazilian Ambassador to the UK, to discuss the co-development of a Malaria vaccine and advance public health outcomes in Brazil.

10 Apr 2024

Pioneering study launched to examine how the immune system responds to repeated malaria infections

Scientists at the University of Oxford and the University of Edinburgh have launched a pioneering study that examines how the immune system responds to repeated malaria infections.

10 Apr 2024

Systematic reviews find inadequate evidence on the use of puberty blockers and hormones for gender distress

The evidence on the use of puberty blockers and hormones for children and young people experiencing gender related distress is wholly inadequate, making it impossible to gauge their effectiveness or their impact on mental and physical health, find two systematic reviews of the available research, published in the Archives of Disease in Childhood.

10 Apr 2024

New screening tools boost early detection of language delays in children

New screening tools in child health care are effective in identifying early language and communication difficulties in children.

2 Apr 2024

Parental touch can relieve acute procedural pain in neonates and parents' anxiety

The Neuroimaging Group, at the Department of Paediatrics, in collaboration with Bliss, the charity for babies born premature or sick, has launched a new suite of information resources for parents of neonates, designed to make them feel more confident about being involved in the care of their babies.

13 Mar 2024

COVID-19 transmission from mothers to newborns is low, study reveals

A study by KK Women's and Children's Hospital (KKH), Singapore General Hospital (SGH) and National University Hospital (NUH) has revealed that COVID-19 transmission from mothers to their newborns is low.

11 Mar 2024

New animation series launched to improve parental understanding of brain development in premature infants

Professor Caroline Hartley, Principal Investigator, and Dr Marianne van der Vaart, Postdoctoral Researcher, in the Paediatric Neuroimaging Group at the Department of Paediatrics, have today launched a series of animations aimed at improving parental understanding of brain development in premature infants, and the effect it has on breathing and apnoeas (the cessation of breathing).

7 Mar 2024

SickKids study offers new path for pediatric rare disease clinical trials

Using a novel methodology, researchers at The Hospital for Sick Children (SickKids) are the first in pediatric research to use data from an international real-world cohort to overcome the barriers associated with conducting randomized clinical trials in children with rare diseases.

29 Feb 2024

Paediatrics News and Research

New cell therapy offers effective treatment for patients with T-cell acute lymphoblastic leukemia

Simple intervention can prevent lifelong disability in premature babies

ANNs can identify lung disease in preterm infants by analyzing sleep breathing patterns

Young people with chronic pain more likely to have clinical anxiety or depression

ChatGPT outperforms trainee doctors in respiratory disease assessments

Exclusive breastfeeding aids postpartum weight loss

World's first rapid TBI blood test debuts at Orlando Health

A close collaboration to help children suffering from cancer

Baby boys more likely to achieve HIV cure or remission after in-utero infection

Study unveils crucial insights into how COVID-19 vaccines mitigate severe illness

Real-world data validates gene therapy for spinal muscular atrophy

Cystic fibrosis drug found to be safe and effective in newborns

Oxford University and Brazil partner to advance malaria vaccine development

Pioneering study launched to examine how the immune system responds to repeated malaria infections

Systematic reviews find inadequate evidence on the use of puberty blockers and hormones for gender distress

New screening tools boost early detection of language delays in children

Parental touch can relieve acute procedural pain in neonates and parents' anxiety

COVID-19 transmission from mothers to newborns is low, study reveals

New animation series launched to improve parental understanding of brain development in premature infants

SickKids study offers new path for pediatric rare disease clinical trials

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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