Pancreas News and Research

RSS

The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

Gene blockade could reverse type 2 diabetes: Study

Australian scientists report that they may be on the brink of reversing type 2 diabetes after a genetic discovery. The finding centers on how a particular gene responds to high-fat diets by disrupting insulin production in the pancreas and triggering diabetes.

26 Sep 2011

Cedars-Sinai inaugurates new facility to generate induced pluripotent stem cells

The Cedars-Sinai Regenerative Medicine Institute has opened a new Induced Pluripotent Stem Cell (iPSC) Core Facility to produce powerful cells capable of making all tissues of the body from adult human skin cells.

23 Sep 2011

First ever domino liver transplant

For the first time ever, a surgical team led by Alan Hemming, MD, has successfully performed a domino transplant using a liver with a rare genetic disorder called methylmalonic acidemia.

22 Sep 2011

GI Dynamics introduces EndoBarrier Gastrointestinal Liner in Austria

GI Dynamics, Inc. today announced the launch of the EndoBarrier Gastrointestinal Liner in Austria, the establishment of the first two Centers of Excellence and the treatment of patients at each new Center.

21 Sep 2011

Vigorous exercise results in stronger bones, reduced diabetes risk and less visceral fat

Cells in bone, fat and the pancreas appear to be talking to each other and one thing they likely are saying is, "Get moving."

20 Sep 2011

Neuroticism affects brain processing during anticipation and experience of pain

Neuroticism - the tendency to experience negative emotions -significantly affects brain processing during pain, as well as during the anticipation of pain, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. Neuroticism tends to be higher in patients with irritable bowel syndrome (IBS), and is a risk factor for chronic, unexplained pain in IBS.

20 Sep 2011

Two newer Type 2 diabetes drugs could be linked to increased risk of pancreatic cancer

Two newer drugs used to treat Type 2 diabetes could be linked to a significantly increased risk of developing pancreatitis and pancreatic cancer, and one could also be linked to an increased risk of thyroid cancer, according to a new UCLA study.

19 Sep 2011

High-fat maternal diet during pregnancy results in deposition of excess body fat in the newborn

New research in mice indicates that babies born to moms who eat a high-fat diet before and during pregnancy have a higher fat mass and smaller livers than babies whose moms consume low-fat fare, according to scientists at Oregon Health & Science University Doernbecher Children's Hospital.

17 Sep 2011

New diabetes drugs linked to increased risk of pancreatitis and pancreatic cancer

17 Sep 2011

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Bristol-Myers Squibb Company and AstraZeneca today announced results from an investigational Phase 3b clinical study in which the addition of ONGLYZA (saxagliptin) 5 mg to ongoing insulin therapy (with or without metformin) maintained reductions of blood sugar levels (glycosylated hemoglobin levels, or HbA1c) in adult patients with type 2 diabetes compared to the addition of placebo (with or without metformin) from 24 to 52 weeks.

16 Sep 2011

Uterine stem cells could help treat diabetes

Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published in the journal Molecular Therapy.

15 Sep 2011

Delcath announces updated Phase 2 trial results from metastatic neuroendocrine tumor cohort

Delcath Systems, Inc. announced that updated results from the metastatic neuroendocrine tumor (mNET) cohort of the Company's recently completed Phase 2 clinical trial were presented at the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) congress held this week in Munich, Germany.

13 Sep 2011

Researchers identify glucokinase triggers beta cell regeneration in pancreas

Researchers at the Hebrew University of Jerusalem have identified the key signal that prompts production of insulin-producing beta cells in the pancreas -- a breakthrough discovery that may ultimately help researchers find ways to restore or increase beta cell function in people with type 1 diabetes.

12 Sep 2011

InnoCentive, JDRF announce $100,000 Challenge to uncover solutions for insulin-dependent diabetes

The Juvenile Diabetes Research Foundation (JDRF), the worldwide leader for research to cure, treat, and prevent type 1 diabetes, and InnoCentive, Inc., the pioneer in open innovation and crowdsourcing, today announced a $100,000 Challenge calling for innovative ways to approach the discovery and development of a glucose-responsive insulin drug as a means to treat insulin-dependent diabetes.

9 Sep 2011

SFDA approves MedWaves' AveCure microwave coagulation-ablation system for cancer

MedWaves' AveCure microwave coagulation-ablation (MWA) system uses microwave energy to volumetrically coagulate-ablate (destroy) soft-tissue lesions safely, effectively, precisely and with repeatability.

7 Sep 2011

Pancreatic mesenchyme plays central role in the formation of mature beta cells

A somewhat mysterious soft tissue found in the fetus during early development in the womb plays a pivotal role in the formation of mature beta cells the sole source of the body's insulin. This discovery, made by scientists at University of California, San Francisco (UCSF) and Texas A&M University, may lead to new ways of addressing Type 1 and Type 2 diabetes.

7 Sep 2011

Scientists uncover new ways to stimulate pancreatic beta cell growth

One of the holy grails in diabetes research is to discover molecules that stimulate beta cell growth and to find drugs that target these molecules. Now, JDRF-funded researchers in collaboration with the pharmaceutical company Hoffmann-La Roche, have done both, discovering not only a protein that regulates beta cell growth, but also a chemical compound that stimulates it.

7 Sep 2011

First report of alternative lengthening of telomeres in human cancer subtypes

The first report of the presence of alternative lengthening of telomeres (ALT) in cancers arising from the bladder, cervix, endometrium, esophagus, gallbladder, liver, and lung was published today in The American Journal of Pathology. The presence of ALT in carcinomas can be used as a diagnostic marker and has implications for the development of anti-cancer drug therapies.

3 Sep 2011

Results of Aeterna Zentaris' AEZS-131 anticancer Erk inhibitor presented at ACS 2011 meeting

Aeterna Zentaris Inc. today announced that a poster on its novel orally active anticancer Erk inhibitor, which includes AEZS-131, was presented at the 242nd American Chemical Society National Meeting held at the Colorado Convention Center in Denver, Colorado.

30 Aug 2011

Zinc may act as tumor suppressor in commonist form of pancreatic cancer

The essential element zinc has been shown in a new study to be a likely tumor suppressor in the commonist form of pancreatic cancer, University of Maryland scientists report in the current issue of the journal Cancer Biology & Therapy.

26 Aug 2011

Pancreas News and Research

Further Reading

Gene blockade could reverse type 2 diabetes: Study

Cedars-Sinai inaugurates new facility to generate induced pluripotent stem cells

First ever domino liver transplant

GI Dynamics introduces EndoBarrier Gastrointestinal Liner in Austria

Vigorous exercise results in stronger bones, reduced diabetes risk and less visceral fat

Neuroticism affects brain processing during anticipation and experience of pain

Two newer Type 2 diabetes drugs could be linked to increased risk of pancreatic cancer

High-fat maternal diet during pregnancy results in deposition of excess body fat in the newborn

New diabetes drugs linked to increased risk of pancreatitis and pancreatic cancer

ONGLYZA used with insulin maintains improvement in glucose control in adults with type 2 diabetes

Uterine stem cells could help treat diabetes

Delcath announces updated Phase 2 trial results from metastatic neuroendocrine tumor cohort

Researchers identify glucokinase triggers beta cell regeneration in pancreas

InnoCentive, JDRF announce $100,000 Challenge to uncover solutions for insulin-dependent diabetes

SFDA approves MedWaves' AveCure microwave coagulation-ablation system for cancer

Pancreatic mesenchyme plays central role in the formation of mature beta cells

Scientists uncover new ways to stimulate pancreatic beta cell growth

First report of alternative lengthening of telomeres in human cancer subtypes

Results of Aeterna Zentaris' AEZS-131 anticancer Erk inhibitor presented at ACS 2011 meeting

Zinc may act as tumor suppressor in commonist form of pancreatic cancer

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News