Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

Enrollment stopped in one of two global necitumumab Phase III studies in NSCLC

Eli Lilly and Company and Bristol-Myers Squibb Company announced today that they have stopped enrollment in one of their two global Phase III studies evaluating necitumumab, an investigational anti-cancer agent, as a first-line treatment for advanced non-small cell lung cancer (NSCLC).

3 Feb 2011

New study to address causes and risk factors of ovarian cancer in African American women

University Hospitals Case Medical Center and Case Western Reserve University School of Medicine are conducting an important new study addressing the lack of knowledge about causes and risk factors for ovarian cancer in African American women. The five-year study is funded by the National Cancer Institute through Case Western Reserve University School of Medicine.

2 Feb 2011

New robotic technique can better predict tumors during radiotherapy, prevent severity of side effects

Medical physicists at Thomas Jefferson University and Jefferson's Kimmel Cancer Center have demonstrated a new real-time tumor tracking technique that can help minimize the amount of radiation delivered to surrounding healthy tissue in a patient—up to 50 percent less in some cases—and maximize the dose the tumor receives.

2 Feb 2011

American Cancer Society reports racial disparity continues to increase death rate for some cancers

While the overall death rate for cancer continues to drop among African Americans, the group continues to have higher death rates and shorter survival of any racial and ethnic group in the U.S. for most cancers. The findings come from Cancer Facts & Figures for African Americans 2011-2012, the latest edition of a report produced every two years by the American Cancer Society.

1 Feb 2011

Budget woes lead states to seek ways to ease Medicaid's requirements

While The Hill reports that CMS administrator Donald Berwick says his agency is trying to help states find solutions, National Journal notes that mounting budgetary pressure has put the program in "dire fiscal straits."

29 Jan 2011

PCMD forms 6M research and analysis network to investigate role of virus infection in type 1 diabetes

The Peninsula College of Medicine and Dentistry (PCMD), University of Exeter, is one of 13 academic institutions and businesses across Europe to form a -6m research and analysis network, funded by the EU for a five-year period, which is designed to investigate the possible role of virus infection in the cause of type 1 diabetes.

28 Jan 2011

Researchers discover new sensory neurons that mediate BP and metabolism regulation in liver

For 60 years, scientists have puzzled over the possibility of a hepatic osmoreceptor that influences blood pressure regulation. Now, researchers of the Max Delbr-ck Center for Molecular Medicine Berlin-Buch, the Experimental and Clinical Research Center of the MDC and Charit- and the Hannover Medical School appear to have made a breakthrough discovery.

27 Jan 2011

Elimination of glucagon action may help convert Type 1 diabetes into non-insulin-dependent disorder

Type 1 diabetes could be converted to an asymptomatic, non-insulin-dependent disorder by eliminating the actions of a specific hormone, new findings by UT Southwestern Medical Center researchers suggest.

27 Jan 2011

Raptor completes enrollment in DR Cysteamine Phase 3 clinical trial in cystinosis

Raptor Pharmaceutical Corp., today announced it has completed enrollment in its Phase 3 clinical trial of its proprietary delayed-release oral formulation of cysteamine bitartrate ("DR Cysteamine") in patients with nephropathic cystinosis ("cystinosis").

24 Jan 2011

FibroGen announces FG-3019 interim results from phase 1/2 trial against pancreatic cancer

FibroGen, today announced interim results of a phase 1/2 trial of FG-3019, a therapeutic antibody against connective tissue growth factor, in combination with gemcitabine and erlotinib in individuals with unresectable pancreatic cancer.

23 Jan 2011

Immunomedics reports encouraging results from Y-90-labeled clivatuzumab tetraxetan study in pancreatic cancer

Immunomedics, Inc., a biopharmaceutical company primarily focused on the development of monoclonal antibody-based products for the targeted treatment of cancer, autoimmune and other serious diseases, today announced that repeated therapy cycles of its proprietary antibody, clivatuzumab tetraxetan, labeled with yttrium-90 plus low-dose gemcitabine, extended median overall survival.

21 Jan 2011

Additional data from HyperAcute Pancreas cancer immunotherapy Phase 2 trial to be presented at ASCO 2011

NewLink Genetics Corporation today announced that additional data from its Phase 2 clinical trial of the company's investigational HyperAcute® Pancreas cancer immunotherapy will be presented during a poster session at the American Society of Clinical Oncology 2011 Gastrointestinal Cancers Symposium in San Francisco, California.

21 Jan 2011

Researchers discover several key mutations in pancreatic neuroendocrine tumors

Through a grant provided by the Caring for Carcinoid Foundation, researchers at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center have discovered several key mutations in pancreatic neuroendocrine tumors.

21 Jan 2011

Scientists decipher genetic code for a pancreatic cancer type

Scientists at Johns Hopkins have deciphered the genetic code for a type of pancreatic cancer, called neuroendocrine or islet cell tumors. The work, described online in the Jan. 20 issue of Science Express, shows that patients whose tumors have certain coding "mistakes" live twice as long as those without them.

21 Jan 2011

Successful larynx transplant for Californian woman

In a breakthrough, a surgical team in California on Thursday announced that they had successfully replaced the larynx of a 52-year-old woman who hadn’t been able to speak or breathe on her own for more than a decade.

20 Jan 2011

Data on Ensituximab for treatment of pancreatic and colorectal cancers to be presented at ASCO 2011

Neogenix Oncology announced today that Dr. Luis Diaz of The Johns Hopkins University Hospital will present data from Ensituximab, the company's novel, therapeutic antibody to treat pancreatic and colorectal cancers. The presentation is scheduled at the American Society of Clinical Oncology (ASCO) 2011 Gastrointestinal Cancers Symposium to be held January 20-22, 2011 at the Moscone Center in San Francisco, CA, USA.

19 Jan 2011

MGH researchers discover massive overexpression of DNA sequences in cancer cells

Massachusetts General Hospital Cancer Center researchers have discovered a previously unknown feature of common tumor cells - massive overexpression of certain DNA sequences that do not code for proteins.

14 Jan 2011

Research study to develop rapid, inexpensive blood screening test for early diagnosis of pancreatic cancer

A clinical research study to develop a rapid and inexpensive blood screening test for the early diagnosis of pancreatic cancer has been launched by Henry Ford Health System and the Barbara Ann Karmanos Cancer Institute.

14 Jan 2011

NIH awards VistaGen and NuPotential $500,000 grant to advance iPS stem cell technology

VistaGen Therapeutics, Inc. and NuPotential, Inc. today announced that the National Heart, Lung and Blood Institute of the U.S. National Institutes of Health (NIH) has awarded to the companies a grant of approximately $500,000 to accelerate development of novel and safer approaches to generate patient-specific induced pluripotent stem (iPS) cells for regenerative medicine, drug discovery and drug rescue.

13 Jan 2011

FDA Advisory Committee recommends non-approval of liprotamase for exocrine pancreatic insufficiency

Eli Lilly and Company announced the U.S. Food and Drug Administration (FDA) Gastrointestinal Drugs Advisory Committee voted today to recommend non-approval of liprotamase, a non-porcine pancreatic enzyme replacement therapy (PERT), currently under FDA review for the treatment of exocrine pancreatic insufficiency (EPI).

13 Jan 2011

Pancreas News and Research

Further Reading

Enrollment stopped in one of two global necitumumab Phase III studies in NSCLC

New study to address causes and risk factors of ovarian cancer in African American women

New robotic technique can better predict tumors during radiotherapy, prevent severity of side effects

American Cancer Society reports racial disparity continues to increase death rate for some cancers

Budget woes lead states to seek ways to ease Medicaid's requirements

PCMD forms 6M research and analysis network to investigate role of virus infection in type 1 diabetes

Researchers discover new sensory neurons that mediate BP and metabolism regulation in liver

Elimination of glucagon action may help convert Type 1 diabetes into non-insulin-dependent disorder

Raptor completes enrollment in DR Cysteamine Phase 3 clinical trial in cystinosis

FibroGen announces FG-3019 interim results from phase 1/2 trial against pancreatic cancer

Immunomedics reports encouraging results from Y-90-labeled clivatuzumab tetraxetan study in pancreatic cancer

Additional data from HyperAcute Pancreas cancer immunotherapy Phase 2 trial to be presented at ASCO 2011

Researchers discover several key mutations in pancreatic neuroendocrine tumors

Scientists decipher genetic code for a pancreatic cancer type

Successful larynx transplant for Californian woman

Data on Ensituximab for treatment of pancreatic and colorectal cancers to be presented at ASCO 2011

MGH researchers discover massive overexpression of DNA sequences in cancer cells

Research study to develop rapid, inexpensive blood screening test for early diagnosis of pancreatic cancer

NIH awards VistaGen and NuPotential $500,000 grant to advance iPS stem cell technology

FDA Advisory Committee recommends non-approval of liprotamase for exocrine pancreatic insufficiency

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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