Pancreatitis News and Research

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Pancreatitis is inflammation of the pancreas. The pancreas is a large gland behind the stomach and close to the duodenum—the first part of the small intestine. The pancreas secretes digestive juices, or enzymes, into the duodenum through a tube called the pancreatic duct. Pancreatic enzymes join with bile—a liquid produced in the liver and stored in the gallbladder—to digest food. The pancreas also releases the hormones insulin and glucagon into the bloodstream. These hormones help the body regulate the glucose it takes from food for energy.

Normally, digestive enzymes secreted by the pancreas do not become active until they reach the small intestine. But when the pancreas is inflamed, the enzymes inside it attack and damage the tissues that produce them.

Pancreatitis can be acute or chronic. Either form is serious and can lead to complications. In severe cases, bleeding, infection, and permanent tissue damage may occur.

Endoscopic ultrasound-guided therapy safe for severe gastrointestinal bleeding patients

A new Mayo Clinic study found that endoscopic ultrasound-guided therapy appears to be a safe and effective treatment for patients with severe gastrointestinal bleeding for whom conventional therapies have failed.

21 Feb 2008

Probiotics help keep elite athletes fit and well

According to the latest Australian research the immune system of long-distance runners was enhanced by probiotics - dietary supplements containing potentially beneficial bacteria or yeasts.

13 Feb 2008

Early surgical treatment contributes to better outcomes in gallstone pancreatitis cases

Although delaying surgical treatment remains the standard of care for patients with severe gallstone pancreatitis, a new study published in the December issue of the Journal of the American College of Surgeons shows that, contrary to widespread belief, early cholecystectomy -- or surgical removal of the gallbladder -- significantly reduces hospital stays in patients with mild to moderate gallstone pancreatitis with no increase in complications or mortality.

20 Dec 2007

New understanding on alcohol's role in developing alcoholic chronic pancreatitis

Chronic, excessive alcohol consumption is a major risk factor for developing chronic pancreatitis (pancreatic inflammation).

18 Dec 2007

Gene variants behind pancreatic stone formation

Stone formation is an important feature of chronic pancreatitis, especially tropical calcific pancreatitis (TCP), where the stones are large in size, highly irregular in shape and cause enormous tissue destruction.

14 Nov 2007

Large dose dexamethasone plays important roles in severe acute pancreatitis

Severe acute pancreatitis (SAP) is a fatal systemic disease featuring acute onset, serious conditions, high incidence of complications and 20 - 30% mortality, mainly due to multiple organ failure at its early stage.

5 Nov 2007

Is it pancreatitis in acute abdominal pain in acute viral hepatitis?

Hepatitis viruses have a strong tropism for hepatocytes; viral antigen also has been detected in pancreas and gallbladder.

1 Nov 2007

Exclusion of common bile duct stones prior to gallstone operations

CBDS occur in 7-20% of all patients undergoing a gallstone operation and may complicate the course of surgery.

1 Nov 2007

Acute pancreatitis and cholangitis

Percutaneous endoscopic gastrostomy (PEG) is generally considered to be safe with a low rate of serious complications.

25 Oct 2007

Baicalin shows promise for severe acute pancreatitis

¡°Qingyitang¡±, a representative prescription of Traditional Chinese Medicine for SAP was widely used in the orients countries.

18 Oct 2007

New analyses of long-term LIALDA (mesalamine) data presented at ACG

Post-hoc and other analyses of secondary endpoints of a long-term safety and tolerability study of Shire plc's ulcerative colitis (UC) drug LIALDA (mesalamine) provide further data on LIALDA in patients with mild to moderate ulcerative colitis.

16 Oct 2007

Mortality rates 71 percent lower at top-rated hospitals

Patients have on average a 71 percent lower chance of dying at the nation's top-rated hospitals compared with the lowest-rated hospitals across 18 procedures and conditions analyzed in the tenth annual HealthGrades Hospital Quality in America Study, issued today by HealthGrades, the healthcare ratings company.

16 Oct 2007

A tumor marker Ca 19-9 in diabetics can lead to misdiagnosis of pancreatic cancer

Diabetes is increasing all over the world along with the increase of obesity and associated diseases and is a well-known risk factor for pancreatic cancer. The incidence of pancreatic cancer is also increasing and has one of the lowest survival rates of all cancers.

16 Oct 2007

Short-term hemofiltration is cost-effective for severe acute pancreatitis

Early nasogastric enteral nutrition is a breakthrough in the management of severe acute pancreatitis.

15 Oct 2007

New guide on pancreatic cancer

A new guide on pancreatic cancer, co-authored by the chair of Surgery at Thomas Jefferson University Hospital, offers a better understanding to patients and caregivers of the unique challenges associated with a diagnosis of pancreatic cancer.

8 Oct 2007

Improving diagnosis of pancreatic cancer

In the August issue of Molecular & Cellular Proteomics, scientists provide the first large-scale identification of proteins that are overexpressed in chronic pancreatitis, an inflammatory condition of the pancreas that shares many features with pancreatic cancer.

30 Aug 2007

New detection techniques for pancreatic cancer

Using novel light-scattering techniques, researchers have found the first evidence that early stage pancreatic cancer causes subtle changes in part of the small intestine.

3 Aug 2007

Screening method for pancreatic cancer in asymptomatic patients

EVANSTON, Ill. --- Optical technology developed by a Northwestern University biomedical engineer shown to be effective in the early detection of colon cancer now appears promising for detecting pancreatic cancer, the fourth most common cause of cancer deaths in the United States.

2 Aug 2007

Gene therapy offers promising approach to tackle pancreatic cancer

A molecularly engineered therapy selectively embeds a gene in pancreatic cancer that shrinks or eradicates tumors, inhibits metastasis, and prolongs survival with virtually no toxicity, researchers from The University of Texas M. D. Anderson Cancer Center report in the July 9 edition of Cancer Cell.

10 Jul 2007

Levels of protein CA 19-9 in blood predicts pancreatic cancer outcome after surgery

A team of researchers, led by surgeons at the Kimmel Cancer Center at Jefferson in Philadelphia, has found further evidence supporting the ability of a protein to predict how well a patient with advanced pancreatic cancer will do after surgery, chemotherapy and radiation.

23 Jun 2007