Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Challenges and opportunities for better lung cancer care for the elderly

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 17, entitled, "Promising trends in lung cancer care, but are we overlooking the majority?"

28 Sep 2023

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.

28 Sep 2023

SARS-CoV-2 infects coronary vessels, inducing plaque inflammation

SARS-CoV-2, the virus that causes COVID-19, can directly infect the arteries of the heart and cause the fatty plaque inside arteries to become highly inflamed, increasing the risk of heart attack and stroke, according to a study funded by the National Institutes of Health.

28 Sep 2023

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

28 Sep 2023

Examining the cardiac pathology in fatal cases of yellow fever

The characteristics of yellow fever (YF)-related myocardial damage.

28 Sep 2023

Blocking Notch signaling pathway could reverse age-related bone loss

A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.

27 Sep 2023

New imaging agent predicts early metabolic response to HER2-targeted therapy in metastatic breast cancer

A new imaging agent, 68Ga-ABY-025, can predict early metabolic response to human epidermal growth factor receptor 2 (HER2)-targeted treatment in HER2-positive metastatic breast cancer patients, according to new research published in the September issue of The Journal of Nuclear Medicine.

27 Sep 2023

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

Researchers utilize imaging findings to elucidate how Alzheimer's dementia can present considerable variations depending on the sex of the individual.

27 Sep 2023

$10.2M NIH grant awarded to study risk factors for malignant arrhythmias in mitral valve prolapse

Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a $10.2 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to investigate risk factors for malignant arrhythmias in mitral valve prolapse.

26 Sep 2023

SwRI and UTSA develop breath analysis techniques to detect TBI

Researchers from Southwest Research Institute (SwRI) and The University of Texas at San Antonio (UTSA) are developing techniques to detect traumatic brain injury (TBI) by analyzing breath for specific biomarkers.

26 Sep 2023

Living donor liver transplantation improves waitlist outcomes in high-risk cirrhosis patients

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 17, entitled, "Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients."

26 Sep 2023

Study aims to cast light on the impact of combined alcohol and e-cigarette use on blood brain barrier

With a variety of flavors and widespread perceptions of safety, e-cigarettes appeal to an array of users and especially to adolescents. E-cigarette use, however, is linked to increased alcohol consumption, as well as the use of other substances and drugs.

26 Sep 2023

Intranasal vaccine shows promise against COVID variants in hamsters

Intranasal mRNA-LNP vaccines show promise in Syrian golden hamsters, effectively reducing SARS-CoV-2 viral loads and lung pathology. The study suggests potential efficacy against new variants, setting the stage for future research in human applications.

25 Sep 2023

New AI model improves accuracy of tumor removal in breast cancer surgery

Artificial intelligence (AI) and machine learning tools have received a lot of attention recently, with the majority of discussions focusing on proper use.

25 Sep 2023

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy-;one that boosts T cells, and another that boosts dendritic cells-;can control tumors in preclinical models of triple negative breast cancer, a cancer type that's typically resistant to immunotherapy alone.

25 Sep 2023

Engineered mice reveal how Omicron subvariant BA.5 is more virulent

New research used engineered mice to compare SARS-COV-2 omicron subvariants and found one of them – BA.5 – was more virulent likely due to its ability to rapidly replicate early during infection.

25 Sep 2023

Future-proof vaccine candidate protects against wide range of coronaviruses

Studies of a 'future-proof' vaccine candidate have shown that just one antigen can be modified to provide a broadly protective immune response in animals.

25 Sep 2023

3DHISTECH at the Comenius University in Slovakia

The Ministry of Health of Slovakia, in cooperation with the Slovak Society of Pathologists, organized a Presentation Day of Digital Pathology Solutions at Comenius University in Bratislava.

From 3DHISTECH Ltd. 25 Sep 2023

3DHISTECH and Epredia open pathology innovation incubator to accelerate advancements in cancer diagnostics

Two leading pathology and diagnostics companies, 3DHISTECH of Hungary and Epredia, a member of PHC Group (headquartered in Japan), announce the opening of the Pathology Innovation Incubator in Budapest to develop methods and equipment for faster and more precise diagnosis of cancer and tumor lesions.

From 3DHISTECH Ltd. 25 Sep 2023

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Researchers compared two commercially available blood tests based on the biomarker p-tau217 for diagnosing Alzheimer's disease in 294 patients. Both tests demonstrated robust diagnostic capabilities, strongly correlating with established Alzheimer's biomarkers from PET scans.

24 Sep 2023

Pathology News and Research

Further Reading

Challenges and opportunities for better lung cancer care for the elderly

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

SARS-CoV-2 infects coronary vessels, inducing plaque inflammation

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Examining the cardiac pathology in fatal cases of yellow fever

Blocking Notch signaling pathway could reverse age-related bone loss

New imaging agent predicts early metabolic response to HER2-targeted therapy in metastatic breast cancer

Vascular risk factors influence cognitive health differently in men and women with Alzheimer's disease

$10.2M NIH grant awarded to study risk factors for malignant arrhythmias in mitral valve prolapse

SwRI and UTSA develop breath analysis techniques to detect TBI

Living donor liver transplantation improves waitlist outcomes in high-risk cirrhosis patients

Study aims to cast light on the impact of combined alcohol and e-cigarette use on blood brain barrier

Intranasal vaccine shows promise against COVID variants in hamsters

New AI model improves accuracy of tumor removal in breast cancer surgery

Radiation therapy combined with two types of immunotherapy could be effective against cold tumors

Engineered mice reveal how Omicron subvariant BA.5 is more virulent

Future-proof vaccine candidate protects against wide range of coronaviruses

3DHISTECH at the Comenius University in Slovakia

3DHISTECH and Epredia open pathology innovation incubator to accelerate advancements in cancer diagnostics

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Arrayed CRISPR Screening for Revolutionizing Target Discovery

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

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