Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Pitt researchers validate comprehensive blood test for Alzheimer's biomarkers

University of Pittsburgh scientists independently validated a new blood test platform that can simultaneously measure more than a hundred biomarkers of Alzheimer's disease.

9 Oct 2024

Study illuminates the origin and progression of bladder cancer

How bladder cancer originates and progresses has been illuminated as never before in a study led by researchers at Weill Cornell Medicine and the New York Genome Center.

9 Oct 2024

Novel antibody shows promise for pain relief in peripheral nerves

Cell surface proteins play a crucial role in cell communication and in sensing changes in the extracellular environment.

9 Oct 2024

Transposable elements found to be dysregulated in Alzheimer's brains, revealing potential targets for therapy

Study reveals widespread dysregulation of transposable elements (TEs) in aging human brains with Alzheimer's disease, using advanced techniques like CRISPR interference to identify TE-related risk genes.

9 Oct 2024

NYU Langone Health transforms pathology with digital imaging technology

NYU Langone Health has launched a digital pathology program, transforming disease diagnosis from microscopes to high-definition images, shareable in real time across the hospital network.

9 Oct 2024

New study links persistent SARS-CoV-2 proteins to long COVID symptoms

Brigham researchers found people with wide-ranging long COVID symptoms were twice as likely to have SARS-CoV-2 proteins in their blood, compared to those without long COVID symptoms.

9 Oct 2024

Replicating Lewy body formation in living neurons to understand Parkinson's disease

Lewy bodies are a hallmark of Parkinson's disease (PD) and other related neurological conditions. Understanding why and how they develop is critical to developing better treatments.

8 Oct 2024

Researchers use AI to reveal sex-based differences in glioblastoma prognosis

For years, cancer researchers have noticed that more men than women get a lethal form of brain cancer called glioblastoma.

7 Oct 2024

Study reveals diverse lengths of luteal phases in healthy women

The current expectation is that every ovulatory menstrual cycle will have a luteal phase (the time from egg released until the next flow) that lasts approximately 14 days.

7 Oct 2024

Understanding behavioral changes in early dementia

When most people think of dementia, including Alzheimer's disease, they probably think of memory loss first.

7 Oct 2024

Epigenetic testing opens new doors for multiple myeloma treatment

Multiple myeloma is a type of blood cancer that appears mainly after the age of sixty. Its incidence, therefore, increases with the aging of the population.

7 Oct 2024

Researchers reveal mechanisms of how CDK12 alterations drive prostate cancer development

When researchers at the University of Michigan Rogel Cancer Center first identified a new subtype of aggressive prostate cancer, they knew they needed to understand how this genetic alteration was driving cancer and how to target it with treatment.

4 Oct 2024

Stem cell transplants show promise for macular hole repair in monkeys

Human stem cell transplants successfully repaired macular holes in a monkey model, researchers report October 3rd in the journal Stem Cell Reports. After transplantation, the macular holes were closed by continuous filling of the space with retinal tissue.

3 Oct 2024

International experts to gather for ALS symposium in Chicago

The 2024 Les Turner Symposium on ALS will be held on Monday, Nov. 4 in Chicago. Hosted by the Les Turner ALS Foundation and the Les Turner ALS Center at Northwestern Medicine, this event will assemble internationally-renowned ALS researchers, clinicians, advocates, and people living with ALS to discuss the latest research and perspectives on the disease.

3 Oct 2024

SWOG S1011 trial questions the benefits of extended lymphadenectomy in bladder cancer

The SWOG S1011 randomized phase 3 trial found no significant improvement in disease-free or overall survival but a higher rate of grade 3-4 adverse events and an increased risk of death in the 90 days after surgery.

3 Oct 2024

New insights into the link between respiratory infections and chronic lung diseases

A 3D reconstruction of a mouse lung four days after infection with fluorescent Sendai virus reveals widespread virus presence (red) and active replication (green).

3 Oct 2024

Epigenetic hallmarks of cancer unveiled in new research

Cancer mortality has just surpassed cardiovascular disease for the first time ever and one in two men, and one in three women, will be diagnosed with some form of the disease in the US, according to the NIH.

1 Oct 2024

The role of FOXM1 and PD-L1 in malignant peripheral nerve sheath tumor resistance

A new mini review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, "Linking FOXM1 and PD-L1 to CDK4/6-MEK targeted therapy resistance in malignant peripheral nerve sheath tumors."

1 Oct 2024

NIH grant supports research on cognitive decline in individuals with Lewy body diseases

Penn Medicine researchers will advance their understanding of the underlying causes of cognitive decline in individuals with Lewy body diseases, like Parkinson's, and identify biomarkers that predict which individuals are more likely to develop dementia with a $18 million grant from the National Institutes of Health/National Institute on Aging.

30 Sep 2024

New insights into astrocytes offer hope for Alzheimer's treatment

A research team led by Dr. Hoon Ryu from the Korea Institute of Science and Technology (KIST, President Sang-Rok Oh) Brain Disease Research Group, in collaboration with Director Justin C. Lee of the Institute for Basic Science (IBS, President Do-Young Noh) and Professor Junghee Lee from Boston University Chobanian & Avedisian School of Medicine, has uncovered a new mechanism involving astrocytes for treating Alzheimer's disease (AD) and proposed a novel therapeutic target.

30 Sep 2024