Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Low-income groups slow to seek treatment for stroke

People with lower incomes are less likely to present at a hospital within 3 hours of stroke symptoms and thus have lower rates of thrombolysis therapy or post-stroke care than their more affluent counterparts, according to a retrospective analysis.

22 Jan 2013

PathCentral announces roll-out of new pathology network

PathCentral, a technology-enabled company dedicated to the success of the international pathology community, and China-based Kindstar Globalgene Technology, Inc., today announced the roll-out of the PathCentral Pathology Network, an online professional pathology network that will enable Kindstar to access US pathologists and facilitate pathology consultations for more than 3,300 hospitals throughout China.

22 Jan 2013

Scientists identify new mechanism that turns CD4 helper T lymphocytes into killer cells

A research team led by the La Jolla Institute for Allergy & Immunology has discovered the mechanism that enables CD4 helper T cells to assume the more aggressive role of killer T cells in mounting an immune attack against viruses, cancerous tumors and other damaged or infected cells.

21 Jan 2013

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

Research led by St. Jude Children's Research Hospital scientists has identified a possible lead in treatment of two childhood leukemia subtypes known for their dramatic loss of chromosomes and poor treatment outcomes.

21 Jan 2013

New model of tau pathology spread

Brain diseases associated with the misformed protein tau, including Alzheimer's disease and frontotemporal lobar degeneration with tau pathologies, are characterized by neurofibrillary tangles (NFTs) comprised of pathological tau filaments.

19 Jan 2013

New math model may help predict colon cancer resistance to chemotherapy

Scientists may be able to better predict which patients with colorectal cancer will respond to chemotherapy using a new mathematical model that measures the amount of stress required for a cancer cell to die without harming healthy tissue. The results of this study are published in Cancer Research, a journal of the American Association for Cancer Research.

19 Jan 2013

Study to determine prevalence of abnormal anal cytology and HPV in at-risk women

A basic connection of statistics lead a researcher at Women & Infants Hospital of Rhode Island to question whether women should be screened for anal cancer during a regular visit to the gynecologist, and what technique is most effective.

18 Jan 2013

Penn Medicine to establish new center for treatment and research of blood diseases

Penn Medicine will establish the Philadelphia region's first dedicated center for the treatment and research of blood diseases by combining the expertise of physicians who specialize in the care of blood disorder patients of all ages along with basic science and clinical researchers who are working to advance treatments for these illnesses.

18 Jan 2013

Potential stem cell therapy for Duchenne’s

Researchers have found that injecting aorta-derived stem cells into the hearts of dystrophin-deficient mice prevents the onset of dilated cardiomyopathy, raising hopes of a potential new treatment approach to prevent or reverse the condition in human Duchenne muscular dystrophy.

17 Jan 2013

U-M researchers to develop disorders of sex development decision-making tools for parents

When a child is born with a disorder of sex development, decisions regarding gender assignment and genital surgery are often made quickly and under pressure.

17 Jan 2013

Tamoxifen can counteract some pathologic features in mouse model of DMD

A new study has found that tamoxifen, a well-known breast cancer drug, can counteract some pathologic features in a mouse model of Duchenne muscular dystrophy (DMD). At present, no treatment is known to produce long-term improvement of the symptoms in boys with DMD, a debilitating muscular disorder that is characterized by progressive muscle wasting, respiratory and cardiac impairments, paralysis, and premature death.

16 Jan 2013

SPECT-CT improves preop foot diagnosis

Research demonstrates the usefulness of radionuclide bone scans with single photon-emission computed tomography and computed tomography for the assessment of patients awaiting foot or angle surgery.

16 Jan 2013

Florida Atlantic University announces $3M gift to endow medical student scholarships

Florida Atlantic University's Charles E. Schmidt College of Medicine has announced a $3 million gift to endow medical student scholarships. The endowment will be named the "Dr. Morton and Cynthia Levitt Endowed Scholarship for Medical Education," and the announcement was made during the Schmidt College of Medicine's inaugural "Your Medical School" celebration honoring Dick and Barbara Schmidt.

16 Jan 2013

Stem cell transplantation prevents decrease in heart function associated with DMD

Researchers have shown that transplanting stem cells derived from normal mouse blood vessels into the hearts of mice that model the pathology associated with Duchenne muscular dystrophy (DMD) prevents the decrease in heart function associated with DMD.

16 Jan 2013

MI-ONCOSEQ program identifies NAB2-STAT6 fusion in solitary fibrous tumors

It started with a 44-year-old woman with solitary fibrous tumor, a rare cancer seen in only a few hundred people each year. By looking at the entire DNA from this one patient's tumor, researchers have found a genetic anomaly that provides an important clue to improving how this cancer is diagnosed and treated.

16 Jan 2013

Jan. issue of Behavioural Neurology features papers on aphasia and hemispatial neglect

Approximately half a million individuals suffer strokes in the US each year, and about one in five develops some form of post-stroke aphasia, the partial or total loss of the ability to communicate. By comparing different types of aphasia, investigators have been able to gain new insights into the normal cognitive processes underlying language, as well as the potential response to interventions.

16 Jan 2013

Novel system could allow broader screening for esophageal cancer, other conditions

Physicians may soon have a new way to screen patients for Barrett's esophagus, a precancerous condition usually caused by chronic exposure to stomach acid. Researchers at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) have developed an imaging system enclosed in a capsule about the size of a multivitamin pill that creates detailed, microscopic images of the esophageal wall. The system has several advantages over traditional endoscopy.

15 Jan 2013

Pathology News and Research

Further Reading

Low-income groups slow to seek treatment for stroke

PathCentral announces roll-out of new pathology network

Scientists identify new mechanism that turns CD4 helper T lymphocytes into killer cells

Scientists identify a possible lead in treatment of two childhood leukemia subtypes

New model of tau pathology spread

New math model may help predict colon cancer resistance to chemotherapy

Study to determine prevalence of abnormal anal cytology and HPV in at-risk women

Penn Medicine to establish new center for treatment and research of blood diseases

Potential stem cell therapy for Duchenne’s

U-M researchers to develop disorders of sex development decision-making tools for parents

Tamoxifen can counteract some pathologic features in mouse model of DMD

SPECT-CT improves preop foot diagnosis

Florida Atlantic University announces $3M gift to endow medical student scholarships

Stem cell transplantation prevents decrease in heart function associated with DMD

MI-ONCOSEQ program identifies NAB2-STAT6 fusion in solitary fibrous tumors

Jan. issue of Behavioural Neurology features papers on aphasia and hemispatial neglect

Novel system could allow broader screening for esophageal cancer, other conditions

Targeted prostate biopsies skew proportion of high-risk cases

Off-label drug ineffective in frontotemporal dementia

UCSF teams to study new ways to reduce childhood mortality and disease in developing nations

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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