Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Prostate Center of Academic Urology receives accreditation from ACR, ASTRO

The Prostate Center of Academic Urology has been awarded a three-year term of accreditation in radiation oncology from the American College of Radiology (ACR) and The American Society for Radiation Oncology.

19 Mar 2012

Paper describes results of BMT in models of Rett Syndrome

A paper published online today in Nature describes the results of using bone marrow transplant (BMT) to replace faulty immune system cells in models of Rett Syndrome. The procedure arrested many severe symptoms of the childhood disorder, including abnormal breathing and movement, and significantly extended the lifespan of Rett mouse models.

19 Mar 2012

Exposure to MEHP shortens reproductive life of female mice

Female mouse fetuses exposed to very high doses of a common industrial chemical that makes plastics more pliable develop significant reproductive alterations and precancerous lesions as they grow up, according to a new toxicology study conducted at Brown University.

17 Mar 2012

HGF/C-MET signaling pathway plays a key role in gestational diabetes development

Researchers at the University of Pittsburgh School of Medicine have identified a cell-signaling pathway that plays a key role in increasing insulin secretion during pregnancy and, when blocked, leads to the development of gestational diabetes.

17 Mar 2012

New guidelines on cervical cancer screening

Many women over the last few decades have gone in for their Pap smear tests each year. Now, two influential groups of medical experts say that having cervical cancer screening once a year is not necessary and, in fact, should be discouraged. Many women can wait as long as five years between screenings, the new guidelines say.

15 Mar 2012

Prostate cancer screening debate continues

Routine tests that help detect prostate cancer actually do reduce the risk of death from the disease, researchers said. Screening is done with a simple blood test that measures levels of prostate-specific antigen, or PSA.

15 Mar 2012

Scientists discover cells that chaperone food antigens in the intestine

With every meal, immune cells in the intestine stand like sentries at a citadel, turning away harmful bacteria but allowing vitamins and nutrients to pass. Now, researchers at Washington University School of Medicine in St. Louis have identified the cells that chaperone food antigens, or proteins, in the intestine so that the immune system doesn't mount an attack.

15 Mar 2012

MAPKAP kinase 2 plays an important role in progression of GIST

Gastrointestinal stroma tumours (GIST) are a very particular challenge for cancer research. For once the tumours, which are mostly located in the stomach, are relatively rare (approx. 100 new cases/year in Austria) and hence are difficult to research. On the other side its behaviour varies quite a lot. While some GIST tumours are relatively harmless, others may become metastatic.

15 Mar 2012

Researchers identify epigenetic signatures within reprogrammed skin cells

A research team has identified epigenetic signatures, markers on DNA that control transient changes in gene expression, within reprogrammed skin cells.

15 Mar 2012

ACS, ASCCP and ASCP release new screening guidelines for cervical cancer

The American Cancer Society (ACS), the American Society for Colposcopy and Cervical Pathology (ASCCP), and the American Society for Clinical Pathology (ASCP) have released new guidelines for the prevention and early detection of cervical cancer.

15 Mar 2012

Bayer HealthCare receives FDA approval for Natazia to treat HMB

Bayer HealthCare Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved a new indication for Natazia (estradiol valerate and estradiol valerate/dienogest) tablets for the treatment of heavy menstrual bleeding (HMB) that is not caused by any diagnosed conditions of the uterus (womb), in women who choose an oral contraceptive (OC) for contraception.

15 Mar 2012

Potential new way to treat rare inherited metabolic disorders

A University of Michigan cell biologist and his colleagues have identified a potential drug that speeds up trash removal from the cell's recycling center, the lysosome.

14 Mar 2012

FDA clears Ventana PR (1E2) image analysis algorithm and digital read applications

Ventana Medical Systems, Inc., a member of the Roche Group, received 510(k) clearance from the U.S. Food and Drug Administration for the VENTANA Companion Algorithm Progesterone Receptor (PR) (1E2) image analysis application used with the VENTANA iScan Coreo Au scanner running VIRTUOSO software.

14 Mar 2012

FTY720 improves locomotor recovery in mice with SCI

A new study suggests that administering FTY720, an oral drug that has shown promise in trials for human multiple sclerosis, significantly improves locomotor recovery in mice with spinal cord injury.

13 Mar 2012

Scientists develop realistic model to explain cellular signal processing

Scientists at the Charité - Universitätsmedizin Berlin and the US National Institutes of Health (NIH) have developed a realistic model for explaining cellular signal processing.

13 Mar 2012

Allon advances into second phase of work in preclinical PD model

Allon Therapeutics Inc. announced today the completion of its first phase of work in a preclinical Parkinson's disease model and advancement into the second phase of work. Both phases are funded by The Michael J. Fox Foundation for Parkinson's Research and carried out by Prof. Marie-Francoise Chesselet's lab at the University of California Los Angeles.

12 Mar 2012

HSS summit: Current classification system for osteoarthritis is inadequate

A recent summit that brought together international multidisciplinary experts has provided a foundation for addressing what is the leading cause of disability in the United States: osteoarthritis.

12 Mar 2012

New Burn Medical Education app for physicians, students

A newly released mobile app designed to educate medical students, physicians and health care workers around the globe on how to care for burn victims is one of a fast-growing number of medical apps being developed at Johns Hopkins Medicine.

12 Mar 2012

APTA honors Women & Infants physical therapist with Elizabeth Noble Award

Wendy Baltzer-Fox, PT, DPT, GCS, WCS, of Cranston, supervisor of Women's Health Physical Therapy Services at Women & Infants Hospital of Rhode Island, has been presented with the Elizabeth Noble Award from the Section on Women's Health American Physical Therapy Association.

12 Mar 2012

Blood vessels that form within brain cancers predominantly not made up of cancer cells

Johns Hopkins scientists have published laboratory data refuting studies that suggest blood vessels that form within brain cancers are largely made up of cancer cells. The theory of cancer-based blood vessels calls into question the use and value of anticancer drugs that target these blood vessels, including bevacizumab (Avastin).

10 Mar 2012