Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Quitting hormone therapy can lead to breast tumor regression

As soon as women quit hormone therapy, their rates of new breast cancer decline, supporting the hypothesis that stopping hormones can lead to tumor regression, according to a report e-published in Cancer Epidemiology, Biomarkers, & Prevention.

29 Feb 2012

Low levels of omega-3 in blood ‘ups’ risk of dementia and brain aging: Study

Researchers looked at 1,575 adults who averaged 67 years old and had no signs of dementia and had not had a stroke. They were given MRI brain scans and a battery of tests to measure memory and thinking abilities; they also had blood drawn to check the level of docosahexaenoic acid (DHA) or omega-3 fatty acids in their red blood cells. Those with the lowest levels of omega-3s showed signs of accelerated aging. They had lower brain volume, indicating shrinkage comparable to two additional years of aging. Compared with those with the highest blood levels of omega-3s, they scored lower on cognitive tests measuring such things as memory, problem solving, abstract thinking and multi-tasking.

28 Feb 2012

Aurora-A protein blocks proper functioning of tumor-suppressor p73

A protein abundantly found in treatment-resistant cancers holds an important tumor-suppressor out of the cell nucleus, where it would normally detect DNA damage and force defective cells to kill themselves, a team of scientists reports in the current Cancer Cell.

28 Feb 2012

LA BioMed to honor Women & Infants physician as 'Legend'

The Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) recently announced that it will honor John E. Buster, MD, associate director of the Center for Reproduction and Infertility at Women & Infants Hospital of Rhode Island and Tufts Medical Center, as one of its three "Legends" this May.

28 Feb 2012

FDA grants 510(k) clearance for Ventana Ki-67 image analysis algorithm

Ventana Medical Systems, Inc., a member of the Roche Group, received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for the VENTANA Companion Algorithm Ki-67 (30-9) image analysis application used with the VENTANA iScan Coreo Au scanner running VIRTUOSO software.

27 Feb 2012

GSK, Angiochem to develop and commercialize LSD treatments

Angiochem announced today a global collaboration with GlaxoSmithKline (GSK) to discover, develop and commercialize treatments for lysosomal storage diseases.

27 Feb 2012

New, less toxic radiotherapy technique specifically targets cancerous tissue

Researchers at the University of Granada and the university hospital Virgen de las Nieves in Granada have developed a new radiotherapy technique that is much less toxic than that traditionally used and only targets cancerous tissue.

24 Feb 2012

MGH Pathology Service selects Corista's Digital Image Management Platform

The Massachusetts General Hospital Pathology Service has chosen Corista's Digital Image Management Platform (DP3) to support its goal of providing clinical review of pathology cases with a digital platform. This new capability will allow MGH clinical experts to extend their reach to remote patients and their physicians for second opinions in real time.

24 Feb 2012

Real beauty and self-esteem begins from within, not from makeup

The Renfrew Center Foundation, a non-profit charitable organization dedicated to advancing the education, prevention, research and treatment of eating disorders, today announced survey results which revealed that nearly half of all women have negative feelings about their image when not wearing makeup and associate a "bare face" with feeling unattractive and insecure.

23 Feb 2012

Maintaining differential diagnosis inclusive of infectious etiology may help save children's life

Neurologic tics and obsessive-compulsive behaviors caused by a bacterial infection in children were once thought to occur exclusively in PANDAS (Pediatric Autoimmune Disease Associated with Streptococcus infections).

23 Feb 2012

Gonadal dysgenesis may also increase risk of gonadal tumors

Pediatric and Developmental Pathology - Gonadal dysgenesis—defective development of the ovaries or testes— may also bring with it an increased risk of gonadal tumors. A recent discovery at the histologic level could help identify cells at risk of conversion into a tumor.

23 Feb 2012

Elevated levels of two TLRs can trigger heart disease and diabetes

UC Davis scientists have uncovered a key suspect in the destructive inflammation that underlies heart disease and diabetes. The new research shows elevated levels of a receptor present on leucocytes of the innate immune response in people at risk for these chronic diseases.

23 Feb 2012

Study examines abdomyosarcoma growth in mouse models of muscular dystrophy

Inflammation, cell division and cell differentiation that occur during skeletal muscle regeneration may provide an ideal environment for the highly malignant tumor, rhabdomyosarcoma to arise. These are the findings from a Nationwide Children's Hospital study that examined rhabdomyosarcoma growth in mouse models of muscular dystrophy.

23 Feb 2012

International effort to define ECG interpretation standards in athletes

On Feb. 13-14, the American Medical Society for Sports Medicine (AMSSM) partnered with the ESC Sports Cardiology Section, the PACES, other leading U.S. cardiologists, BJSM, and F-MARC in an effort to define ECG interpretation standards in athletes and develop a comprehensive online training module for physicians around the world to gain expertise in ECG interpretation and the proper evaluation of ECG abnormalities suggestive of a pathologic cardiovascular disorder.

22 Feb 2012

Researchers discover identical antibiotic resistant genes in soil bacteria and in pathogens from clinics

Disease-causing bacteria's efforts to resist antibiotics may get help from their distant bacterial relatives that live in the soil, new research at Washington University School of Medicine suggests.

21 Feb 2012

Charité launches new EU research project to personalize breast cancer treatment

Adjusting breast cancer therapy to individual patients to avoid ineffective treatment: Charité Universitätsmedizin Berlin and eleven partner institutions from six countries have set this as their goal. They have launched the EU research project RESPONSIFY.

20 Feb 2012

Substituting smokeless tobacco products can save smokers' lives

Substituting smokeless tobacco products can save smokers' lives, and there is a scientific foundation that proves it.

20 Feb 2012

Scientists discover molecular pathway by which maternally inherited deafness appears to occur

Yale scientists have discovered the molecular pathway by which maternally inherited deafness appears to occur: Mitochondrial DNA mutations trigger a signaling cascade, resulting in programmed cell death.

17 Feb 2012

Epilepsy community concerned over AHRQ's AED drug comparison study

Leading representatives of the American Epilepsy Society, American Academy of Neurology, and the Epilepsy Foundation today reported they have grave concerns about the implications and potential misuse of the anticonvulsant (AED) drug comparisons study recently released by the U.S. Agency for Health Research and Quality.

17 Feb 2012

Controversy over psychiatric diagnosis reaches a fever pitch

As the Diagnostic and Statistical Manual of Mental Disorders is revised for the first time since 1994, controversy about psychiatric diagnosis is reaching a fever pitch.

16 Feb 2012