Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Nerve disorder expert Jack Griffin passes away

Jack Griffin, an internationally acclaimed and admired expert on diseases of the peripheral nervous system, founding director of the Johns Hopkins Brain Science Institute, and former director of Hopkins School of Medicine's Department of Neurology, died Saturday, April 16, after a long battle with bladder cancer. He was 69.

18 Apr 2011

Scientists develop new compound for multiple sclerosis treatment

Scientists from the Florida campus of The Scripps Research Institute have developed the first of a new class of highly selective compounds that effectively suppresses the severity of multiple sclerosis in animal models.

18 Apr 2011

Team of researchers study development of mesoderm

During the development of an embryo, a large number of different, specialised cell-types arise from the fertilised egg. The genetic information is identical in all cells of an organism. Different properties of cells arise because the activity of genes is controlled and regulated by so called transcription factors. By switching genes on or off, the body makes muscle cells, bone cells, liver cells and many more.

16 Apr 2011

Study: Low-carb diet greatly reduces liver fat

Curbing carbohydrates is more effective than cutting calories for individuals who want to quickly reduce the amount of fat in their liver, report UT Southwestern Medical Center researchers.

15 Apr 2011

Acute high-fat diets can protect against heart attack

Approximately one million Americans suffer a heart attack each year of which some 400,000 attacks are fatal. A key cause of heart attacks is atherosclerosis, a process in which cholesterol builds up in the arteries and impedes the ability of the blood to flow to our most vital organ.

15 Apr 2011

Researchers classify chronic ulcerative stomatitis as a new autoimmune disease

In the first study investigating the origins of a little-known condition called chronic ulcerative stomatitis, researchers at Tufts University School of Dental Medicine provide evidence that an autoimmune response contributes to the painful oral sores that characterize the disease. The study findings support the classification of CUS as a new autoimmune disease.

15 Apr 2011

Walking slows progression of nonalcoholic fatty liver disease in obese people

Walking on a treadmill for one hour a day may slow the progression of nonalcoholic fatty liver disease in obese people with prediabetes by jump-starting their metabolism and slowing the oxidative damage wrought by the condition, say researchers at the Cleveland Clinic.

15 Apr 2011

Brain damage starts decade earlier in Alzheimer’s patients

A new study published in the journal Neurology has shown that the brains of people diagnosed with Alzheimer's disease start shrinking up to a decade before symptoms appear. Researchers from Rush University Medical Center in Chicago and Massachusetts General Hospital in Boston did brain imaging tests on older adults with no signs of memory loss.

15 Apr 2011

Klotho hormone can protect kidney from renal fibrosis

A natural hormone known to inhibit aging can also protect kidneys against renal fibrosis, UT Southwestern Medical Center researchers have demonstrated.

15 Apr 2011

Changes in hormonal status have no impact on women's voice parameters

In recent years several studies have suggested that women's voices change at different times over the menstrual cycle, with the tone rising as ovulation approaches. Now a study conducted by researchers at the West Texas A&M University in which women's voices were subjected to computerized acoustical analysis contradicts those findings.

12 Apr 2011

Early uMSC transplantation may treat lupus nephritis

Human umbilical cord blood-derived mensenchymal stem cells have been found to offer benefits for treating lupus nephritis when transplanted into mouse models of systemic lupus erythematosus.

12 Apr 2011

Study to discover mysterious biological cause of Gulf War Illness

For nearly two decades following the 1991 Gulf War, doctors noticed a trend in many of veterans of that conflict: an unexplainable cluster of symptoms including but not limited to chronic fatigue, memory loss, and depression. It wasn't until 2008 that a scientific panel from the U.S. Department of Veterans Affairs concluded that a third of American troops who served in the Gulf War were suffering from combinations of these symptoms, now recognized collectively as Gulf War Illness (GWI).

12 Apr 2011

African-American adults with CVD may benefit from 'sunshine vitamin'

In recent years supplementation with Vitamin D has been shown to reduce the risk of cardiovascular disease in people who are deficient in the vitamin.

12 Apr 2011

Study shows neutralizing antibodies to C5a protein may prevent heart failure

New research published online in The FASEB Journal details research in rats and mice that offers hope for stopping the devastating, and often fatal, effects of sepsis in humans. In the study, University of Michigan researchers show how neutralizing the effects of a key protein fragment, called C5a, used by the immune system to attract white blood cells may ultimately prevent heart failure.

12 Apr 2011

Obesity impacts gene clock of cardiovascular system

Obese individuals typically suffer more medical problems than their leaner counterparts. They are more likely to be diagnosed with insulin resistance, diabetes, increased stress hormones, hypothyroidism, and sleep apnea. Researchers at the Georgia Health Sciences University in Augusta have also found the potential for something else, using an animal model.

12 Apr 2011

Researchers discover new mechanism underlying esophageal cancer

A gene thought to be associated with cancer development can be a tumor suppressor gene in mice, researchers have discovered. Understanding which genes are involved in spreading cancer could lead to future therapies.

12 Apr 2011

Research on rare cancers

A cancer diagnosis can be a life-changing event. Many questions arise, with one of the first being, "Where should I be treated?" Patients diagnosed with rare cancers may have difficulty finding a physician knowledgeable in treating their type of cancer.

11 Apr 2011

Study on 'health halo effect'

Jenny Wan-chen Lee, a graduate student in Cornell University's Dyson School of Applied Economics and Management, has been fascinated with a phenomenon known as "the halo effect" for some time.

11 Apr 2011

Tai chi, green tea may help reduce inflammatory diseases in postmenopausal women

C.S. Lewis, the famous author and Oxford academic, once proclaimed "You can't get a cup of tea big enough or a book long enough to suit me." We sip it with toast in the morning, enjoy it with sweets and biscuits in the afternoon, and relax with it at the end of the day.

11 Apr 2011

Takeda, Heptares collaborate to develop new drugs against CNS disorders

Heptares Therapeutics and Takeda Pharmaceutical Company today announced the formation of a two-year drug discovery collaboration focused on a single G-protein coupled receptor that plays an important role in the pathology of central nervous system disorders.

11 Apr 2011