Pathophysiology News and Research

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Cayetano Heredia, UT Southwestern sign five-year affiliation agreement

UT Southwestern Medical Center and the Universidad Peruana Cayetano Heredia in Peru have signed a five-year affiliation agreement that establishes an exchange program for medical students and related educational opportunities.

6 Dec 2011

ASH recognizes abstract presenters at 53rd annual meeting in San Diego

The American Society of Hematology (ASH) recognizes the following abstract presenters at the 53rd ASH annual meeting in San Diego, CA, with the highest scoring abstracts in the categories of undergraduate student, medical student, graduate student, resident physician, and postdoctoral fellow.

2 Dec 2011

Study highlights importance of diagnosing 'overlap syndrome' in sufferers of ALS, FTD

In order to better counsel patients, it is key for clinicians of different disciplines to be aware of, and diagnose, the 'overlap syndrome' between two medical disorders - ALS and FTD - since it significantly affects patient survival. In her new study, Catherine Lomen-Hoerth, from the University of California San Francisco in the US, also highlights that from a research perspective, identifying the syndrome early is an opportunity to study damaged nerve cells and understand more about the early stages of both ALS and FTD.

30 Nov 2011

Genetic, lifestyle factors and HRT increase risk of breast cancer

The risk of breast cancer is increased by genetic and lifestyle factors such as the inherited BRCA2 gene, age of having first child, or use of hormone replacement therapy (HRT).

28 Nov 2011

The AJMS launches new series on 'Pathophysiology in Medicine'

As scientific research delves into the processes underlying human disease, doctors are challenged to integrate these new discoveries into patient care. To help bridge the gap between basic science research and clinical practice, a new series on "Pathophysiology in Medicine" begins this month in The American Journal of the Medical Sciences (The AJMS), official journal of the Southern Society for Clinical Investigation.

18 Nov 2011

UM to host Summit on Childhood Obesity at Hilton Baltimore

Science and medical reporters are invited to sample a wide diversity of new research and policy initiatives at a Summit on Childhood Obesity on Tues., Nov. 15 and Wed., Nov. 16 at the Hilton Baltimore.

13 Nov 2011

Study finds spinal bleeding in young children with abusive head trauma

A new study found that spinal bleeding is found often in young children who are victims of abusive trauma. The findings support performing complete spine imaging for children undergoing brain magnetic resonance imaging (MRI) for moderate or severe traumatic brain injury and suggest a pathway for distinguishing between abusive and accidental injury.

8 Nov 2011

Pharmacyclics first quarter GAAP net loss increases to $14.5M

Pharmacyclics, Inc. today reported financial results and recent developments for its fiscal first quarter ended September 30, 2011.

7 Nov 2011

Heidelberg scientists identify single protein responsible for varicose veins

Dr. Thomas Korff and his group at the Division of Cardiovascular Physiology of Heidelberg University's Institute of Physiology and Pathophysiology have now shown that the pathological remodeling processes causing varicose veins are mediated by a single protein.

5 Nov 2011

Impulsive men have lower levels of GABA in dorsolateral prefrontal cortex

Impulsive individuals tend to display aggressive behavior and have challenges ranging from drug and alcohol abuse, to problem gambling and difficult relationships. They are less able to adapt to different social situations. Impulsivity is also a common feature of psychiatric disorders.

4 Nov 2011

Study highlights profound impact of maternal separation on infants

A woman goes into labor, and gives birth. The newborn is swaddled and placed to sleep in a nearby bassinet, or taken to the hospital nursery so that the mother can rest. Despite this common practice, new research published in Biological Psychiatry provides new evidence that separating infants from their mothers is stressful to the baby.

3 Nov 2011

Oscillatory signals in basal ganglia cause motor deficits in Parkinson's

The research group headed by Professor Atsushi Nambu and Professor Masahiko Takada has shown that the 'oscillatory' nature of electrical signals in subcortical nuclei, the basal ganglia, causes severe motor deficits in Parkinson's disease, by disturbing the information flow of motor commands.

1 Nov 2011

Deficits in endocannabinoid function may contribute to eating disorders

A new report in Biological Psychiatry suggests that deficits in endocannabinoid function may contribute to anorexia nervosa and bulimia.

1 Nov 2011

Thyroid researcher to receive ATA's John B. Stanbury Pathophysiology Medal

Each year, the American Thyroid Association (ATA) recognizes the outstanding research contributions of one of its members to a greater understanding of thyroid physiology or the pathophysiology of thyroid disease, with its presentation of the John B. Stanbury Pathophysiology Medal at its Annual Meeting.

29 Oct 2011

New, more effective DBS paradigm may manage Parkinson's symptoms

Parkinson's disease (PD) is a devastating and incurable disease that causes abnormal poverty of movement, involuntary tremor, and lack of coordination. A technique called deep brain stimulation (DBS) is sometimes used to improve motor symptoms in patients with advanced disease. Now, a study published by Cell Press in the October 20 issue of the journal Neuron describes a new and more effective DBS paradigm that makes real-time adjustments in response to disease dynamics and progression and may be better for managing symptoms of advanced PD.

20 Oct 2011

AAWC, ACES to offer online educational opportunity for wound care experts

The Association for the Advancement of Wound Care (AAWC) announces the Virtual Wound - an exciting and unique online educational opportunity for AAWC members through a partnership with Applied Computer Education Services, Inc.

19 Oct 2011

Sex differences in heart disease

Heart disease affects men and women in different ways. In women, symptoms of burgeoning heart disease are often more insidious, but when a heart attack strikes, it is more lethal than it is in men. Roughly 25 percent of men will die within a year of their first heart attack, but among women, 38 percent will die. Women are twice as likely as men to have a second heart attack within 6 years of their first one, and women are twice as likely as men to die after bypass surgery.

15 Oct 2011

Researchers assess new guidelines for preclinical Alzheimer's disease

Addressing the earliest stages of Alzheimer's disease, before a patient shows outward signs of cognitive problems, has sometimes been a challenge for physicians and researchers, in part because they have not been using common and specific terms to describe the disease's initial phases.

11 Oct 2011

Gantenerumab appears to reduce brain amyloid levels in patients with AD

Although it is a small study and more clinical trials are needed, treatment with the medication gantenerumab appeared to result in a reduction in brain amyloid levels in patients with Alzheimer disease, according to a report published Online First by Archives of Neurology, one of the JAMA/Archives journals.

11 Oct 2011

Four-gene signature may predict patients at higher risk of OSCC recurrence

Oral Squamous Cell Carcinoma (OSCC) is responsible for nearly a quarter of all head and neck cancers. It is one of the leading causes of cancer death - largely due to the failure of current histological procedures in predicting the recurrence of the disease. New research published in BioMed Central's open access journal BMC Cancer shows that a four-gene signature may accurately predict which patients are at higher risk of OSCC recurrence.

11 Oct 2011