Peripheral Artery Disease News and Research

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Peripheral arterial disease (PAD) occurs when leg arteries become narrowed or blocked by plaque. These blockages can result in severe pain for patients, limited physical mobility, and life-threatening non-healing leg ulcers. According to the American Heart Association, this condition affects approximately 8 to 12 million Americans. With only about 25 percent of PAD patients undergoing treatment, it is a disease that is largely under-diagnosed and under-treated. If left untreated, PAD can lead to critical leg ischemia, a condition where not enough blood is being delivered to the leg to keep the tissue alive. Total loss of circulation to the legs and feet can cause gangrene and lead to amputation.

Research highlights cardiovascular benefits of semaglutide for overweight adults with impaired kidney function

The anti-obesity medication semaglutide may help to prevent heart attacks, strokes, and other major adverse cardiovascular events (MACE) as well as death in adults with overweight or obesity who don't have diabetes, whether or not they also have impaired kidney function, according to new research to be presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Madrid (9-13 Sept).

13 Sep 2024

Semaglutide reduced mortality in obese patients by lowering infection-related deaths during COVID-19 pandemic

Semaglutide significantly reduces all-cause mortality in non-diabetic obese patients, particularly by lowering infection-related deaths during the COVID-19 pandemic. However, the study's findings should be interpreted with caution due to potential competing risks and unique pandemic circumstances.

5 Sep 2024

Semaglutide shown to cut major adverse cardiovascular events in heart failure patients

Semaglutide shows promise in reducing cardiovascular risks in obese patients with heart failure, improving outcomes in a recent large-scale clinical trial.

27 Aug 2024

New tool could revolutionize cardiovascular risk management: PRESS score validated

The association between platelet hyperreactivity and the risk of cardiovascular events.

22 Aug 2024

Revolutionary platelet score offers better risk assessment for heart attacks

Platelets are circulating cell fragments known to clump up and form blood clots that stop bleeding in injured vessels.

20 Aug 2024

Job strain and effort-reward imbalance linked to higher risk of atrial fibrillation

Work-related stress caused by job strain and an imbalance between efforts applied vs. rewards received may increase the risk of developing atrial fibrillation, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

14 Aug 2024

Beyond the anti-obesity benefits of glucagon-like peptide-1 drugs

The advantages of glucagon-like peptide-1 (GLP-1) medicines beyond glycemic and weight control.

23 Jul 2024

Study reveals age-related differences in amputation rates following PAD surgery

People in their 50s with severe peripheral artery disease or PAD may be more likely than people in their 80s to undergo leg amputation one to five years after emergency surgery to restore blood flow to the lower limbs, according to new research published today in the American Heart Association's flagship journal Circulation.

22 Jul 2024

Semaglutide reduces heart risks in overweight and obese individuals without diabetes

The SELECT trial found that semaglutide significantly reduces cardiovascular events in individuals with overweight or obesity and preexisting cardiovascular disease, regardless of baseline HbA1c or changes in HbA1c levels.

26 Jun 2024

Nicotinamide riboside boosts walking endurance in peripheral artery disease

The over-the-counter supplement nicotinamide riboside, a form of vitamin B3, increased the walking endurance of patients with peripheral artery disease, a chronic leg condition for which there are few effective treatments.

18 Jun 2024

Long-term health risks linger for severe COVID-19 patients three years after hospitalization

Three years after severe COVID-19 hospitalization, significant risks of mortality and long-term symptoms persist, impacting overall health and quality of life.

2 Jun 2024

New joint guideline highlights importance of coordinated care for peripheral artery disease

Timely diagnosis and proper management of peripheral artery disease (PAD), including coordinated care from a multispecialty team, are essential to help prevent amputation and other cardiovascular complications and to allow patients with PAD to live longer lives with better physical function and improved quality of life, according to a new joint guideline published today in the American Heart Association's flagship, peer-reviewed journal Circulation and simultaneously in the Journal of the American College of Cardiology.

14 May 2024

New studies underscore the importance of inclusive approaches in peripheral artery disease treatment

New clinical results highlight the need for inclusive approaches and comprehensive examinations of treatment options for peripheral artery disease (PAD), including endovascular therapy and revascularization.

3 May 2024

IVUS guidance improves angioplasty success rates in patients with peripheral artery disease

One-year success rates from angioplasty procedures to open clogged arteries in the legs were significantly higher among patients whose procedures were guided by intravascular ultrasound (IVUS) alongside angiography compared with those whose procedures were guided by angiography alone, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Migraines and other nontraditional factors linked to higher stroke risk in young adults

Adults younger than 35- to 45-years old may have a higher risk of developing a stroke from nontraditional risk factors such as migraines than from traditional risks like high blood pressure.

26 Mar 2024

Free weekly fresh produce linked to improved nutrition and reduced cardiovascular risk

Programs that provided free, weekly home delivery of fresh fruits and vegetable from local farms helped improve recipients' nutrition levels, physical activity levels and cardiovascular disease risk factors, according to preliminary research to be presented at the American Heart Association's Epidemiology and Prevention│Lifestyle and Cardiometabolic Scientific Sessions 2024, held March 18- 21, in Chicago.

20 Mar 2024

Study reveals alarming cholesterol levels among American Indian adolescents and young adults

Young American Indians, ages 15-39, had cholesterol levels more than two times higher than the general U.S. population, according to new research published in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

8 Mar 2024

Socioeconomic consideration in Medicare penalty calculation could ease financial strain on safety-net hospitals

The Affordable Care Act requires Medicare to issue penalties that reduce payment to hospitals if post-operative readmission rates within 30 days exceed the national average.

12 Feb 2024

Dementia risk can be the highest in the first year after stroke

Having a stroke may significantly increase the risk of developing dementia. The risk of dementia was the highest in the first year after a stroke and remained elevated over a period of twenty years, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2024.

1 Feb 2024

American Heart Association report highlights disparities in heart disease, calls for equitable healthcare

The American Heart Association's report on heart disease and stroke statistics emphasizes health equity and addresses structural racism in healthcare, revealing disparities in cardiovascular risk factors and disease prevalence among different communities.

29 Jan 2024