Peripheral arterial disease (PAD) occurs when leg arteries become narrowed or blocked by plaque. These blockages can result in severe pain for patients, limited physical mobility, and life-threatening non-healing leg ulcers. According to the American Heart Association, this condition affects approximately 8 to 12 million Americans. With only about 25 percent of PAD patients undergoing treatment, it is a disease that is largely under-diagnosed and under-treated. If left untreated, PAD can lead to critical leg ischemia, a condition where not enough blood is being delivered to the leg to keep the tissue alive. Total loss of circulation to the legs and feet can cause gangrene and lead to amputation.
ACIST Medical Systems, Inc., a Bracco Group Company, today announced the global launch of its ACIST RXi Mini System, the next generation system of its RXi Rapid Exchange FFR System. The RXi Mini System will debut at the 29th Transcatheter Cardiovascular Therapeutics scientific symposium in Denver, Colorado.
Stem cell researchers at Emory University School of Medicine have made an advance toward having a long-lasting "repair caulk" for blood vessels. The research could form the basis of a treatment for peripheral artery disease, derived from a patient's own cells. Their results were recently published in the journal Circulation.
Ischemia is a serious medical condition in which the flow of blood and delivery of oxygen to tissues is restricted, thus resulting in pain, weakness, and more seriously, tissue and organ damage. Ischemia in muscle tissue, most commonly as a result of atherosclerosis, leads to life-threatening diseases like coronary artery disease and stroke, but also to chronic peripheral artery disease (PAD).
Rivaroxaban plus aspirin improves survival and reduces stroke and heart attack in patients with stable coronary or peripheral artery disease, according to late-breaking results from the COMPASS trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in the NEJM.
A major international study has found that the combination of two drugs - rivaroxaban and aspirin -- is superior to aspirin alone in preventing further heart complications in people with vascular disease.
European Society of Cardiology Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, developed in collaboration with the European Society for Vascular Surgery (ESVS), are published online today in European Heart Journal, European Journal of Vascular and Endovascular Surgery, and the ESC website.
High blood sugar, also known as hyperglycemia, occurs when the body does not produce enough insulin to turn blood glucose into energy.
Less than half of individuals with peripheral artery disease, which is a narrowing of arteries to the limbs, stomach and head, are treated with appropriate medications and lifestyle counseling. These findings highlight the need to improve the quality of care for this high-risk group of individuals.
Two immune responses are important for recovery after a heart attack -; an acute inflammatory response that attracts leukocyte immune cells to remove dead tissue, followed by a resolving response that allows healing.
Increased activity in a deep-lying region of the brain called the amygdala is associated with a higher risk of heart attack and stroke, according to a study published in The Lancet.
The amygdala is known to process emotions such as fear and anger and the finding sheds light on the possible mechanism by which stress can lead to cardiovascular disease (CVD), say the study authors.
Using technology adapted from NASA's Mars lander as part of a large-scale bedsore reduction program, over half of the 13 participating hospitals were able to eliminate the occurrence of new bedsores completely; an additional 3 hospitals achieved reductions ranging from 11% to 90%.
OrbusNeich has announced the launch of its latest generation Dual Therapy Stent (DTS), the COMBO Plus.
New guidelines for the treatment of peripheral artery disease (PAD), include recommendations on the use of antiplatelet therapy to reduce the risk of blood clots and statin drugs to lower cholesterol and advise PAD patients to participate in a structured exercise program.
A large national study has confirmed the value of high-intensity statin treatments for people with cardiovascular disease, according to researchers at the Stanford University School of Medicine.
Researchers at the University of North Carolina School of Medicine have found a major clue that may explain why some people sustain relatively little damage from strokes or heart attacks despite severe arterial blockages.
In an effort to determine if stem cell therapy can prevent or improve a condition called "diabetic foot" caused by poor blood flow in patients with diabetes, a team of researchers in China has found that transplanting human placenta-derived mesenchymal stem cells (MSCs) into rats modeled with diabetes can affect blood vessel growth, potentially improving blood flow and preventing critical limb ischemia (CLI), a condition that results in diabetic foot and frequently leads to amputation.
MILabs will provide an advanced U-SPECT4CT system to the Yale Translational Research Imaging Center (Y-TRIC) in New Haven-Connecticut, with support of an NIH Shared Instrument Grant for advancing their program in multimodality molecular and translational cardiovascular imaging research.
The short-term risk of developing cardiovascular disease following a first pregnancy is higher for women experiencing placental syndromes and a preterm birth or an infant born smaller than the usual size, a University of South Florida study reports.
A research advance from the Sanford Burnham Prebys Medical Discovery Institute and Stanford University could lead to new drugs that minimize the damage caused by heart attacks.
A first-in-human trial of an everolimus-eluting bioresorbable vascular scaffold has shown that the device can achieve a high 2-year patency rate and low 2-year target lesion revascularisation rate in patients with peripheral artery disease involving the external iliac artery and superficial femoral artery.