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Pomegranate's power: Studies show promise in cardiovascular and diabetic health

Researchers reviewed existing data on the bio-modulatory effects of pomegranate (Punica granatum l., PG) polyphenols on metabolic disorders.

24 Nov 2023

Neural circuits respond to rapid dopamine surges

Researchers assess the pharmacodynamics of dopamine signaling, brain connectivity/activity, and self-documented 'high' following methylphenidate exposure.v

14 Nov 2023

Pharmacogenomics holds promise for personalized dementia therapies

Pharmacogenomics-based studies in the research for personalized therapeutics for dementia

8 Nov 2023

Does your gut microbiome play a role in therapeutic outcomes?

The role of the gut microbiome and its metabolites in altering the therapeutic outcomes

12 Oct 2023

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Researchers examine the mechanisms responsible for the increased risk of neurocognitive impairment in HIV patients and explore potential treatments.

12 Oct 2023

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

The intricate interactions between gut microbiota and drugs.

11 Oct 2023

Improving treatment outcomes for individuals with acute spinal cord injury

A special focus issue of the peer-reviewed Journal of Neurotrauma highlights the latest findings of the North American Clinical Trials Network (NACTN), aimed at improving outcomes for individuals with acute spinal cord injury (SCI).

27 Sep 2023

Can muvalaplin achieve safe and tolerable plasma concentrations adequate to reduce steady-state Lp(a) levels without modulating plasminogen activity in humans?

Researchers evaluated the tolerability, safety, pharmacodynamics, and pharmacokinetic properties of muvalaplin.

30 Aug 2023

Breast cancer drug development work moves forward with support from STTR grant

Triple negative breast cancer is an aggressive subtype of breast cancer with worse survival outcomes than most.

14 Jun 2023

Are quaternary ammonium compounds associated with adverse environmental and health outcomes?

Researchers presented an overview of quaternary ammonium compounds and their environmental and human health concerns.

11 May 2023

Clockwork in cancer: the importance of the circadian rhythm in the formation and progression of tumors

Researchers reviewed the importance of the circadian rhythm in the formation and progression of tumors.

29 Mar 2023

First-in-woman study of a non-hormonal vaginal film showed safety, potential contraceptive efficacy, and supports future development

Researchers developed a novel contraceptive 'ZB-06' a vaginal film containing a human contraceptive antibody called HC4-N that agglutinates sperm.

7 Mar 2023

Study finds high doses of oral CBD can exacerbate THC’s effects by inhibiting THC metabolism

Researchers compare the pharmacokinetics and pharmacodynamics of oral Δ9-tetrahydrocannabinol-dominant and cannabidiol-dominant cannabis extracts that contained the same Δ9-THC dose (20 mg).

24 Feb 2023

High doses of cannabidiol may increase the effects of THC in edible cannabis products

Contrary to some common claims, a study led by Johns Hopkins Medicine researchers found that relatively high doses of cannabidiol (CBD) may increase the adverse effects of delta-9-tetrahydrocannabinol (THC), the main active ingredient in cannabis that can cause a mood alteration or a "high" sensation.

13 Feb 2023

Pharmacodynamics News and Research

Pomegranate's power: Studies show promise in cardiovascular and diabetic health

Neural circuits respond to rapid dopamine surges

Pharmacogenomics holds promise for personalized dementia therapies

Does your gut microbiome play a role in therapeutic outcomes?

Unlocking hope: Promising treatments for cognitive impairment in HIV patients on the horizon

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

Improving treatment outcomes for individuals with acute spinal cord injury

Can muvalaplin achieve safe and tolerable plasma concentrations adequate to reduce steady-state Lp(a) levels without modulating plasminogen activity in humans?

Breast cancer drug development work moves forward with support from STTR grant

Are quaternary ammonium compounds associated with adverse environmental and health outcomes?

Clockwork in cancer: the importance of the circadian rhythm in the formation and progression of tumors

First-in-woman study of a non-hormonal vaginal film showed safety, potential contraceptive efficacy, and supports future development

Study finds high doses of oral CBD can exacerbate THC’s effects by inhibiting THC metabolism

High doses of cannabidiol may increase the effects of THC in edible cannabis products

The therapeutic effects and safety of psychedelics

New fentanyl vaccine could prevent deadly opioid from entering the brain

Exploring molecular docking and molecular dynamics simulations as advanced tools for novel antiviral drug discovery

Are men or women impacted more by adverse reactions to prescription drug treatments?

FDA-approved anti-sedative could alleviate common side effects of cancer treatments

Plants and plant-derived preparations as co-treatments for COVID-19

Drug Discovery - Second Edition eBook

Michael Stryker

The past, present and future of automation and digitalization in the life sciences laboratory

Arxspan BioDrive: A Versatile Solution for Molecular Biology

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