Pharmacogenetics News and Research

RSS
The terms pharmacogenomics and pharmacogenetics are often used interchangeably to describe a field of research focused on how genes affect individual responses to medicines. Whether a medicine works well for you—or whether it causes serious side effects—depends, to a certain extent, on your genes.

Just as genes contribute to whether you will be tall or short, black-haired or blond, your genes also determine how you will respond to medicines. Genes are like recipes—they carry instructions for making protein molecules. As medicines travel through your body, they interact with thousands of proteins. Small differences in the composition or quantities of these molecules can affect how medicines do their jobs.

These differences can be due to diet, level of activity, or the medicines a person takes, but they can also be due to differences in genes. By understanding the genetic basis of drug responses, scientists hope to enable doctors to prescribe the drugs and doses best suited for each individual.
Study identifies genetic marker which could personalize treatment for Crohn's disease

Study identifies genetic marker which could personalize treatment for Crohn's disease

Common genetic variant explains why immunotherapy often fails in Crohn's disease

Common genetic variant explains why immunotherapy often fails in Crohn's disease

AMP offers recommendations to aid in design and validation of clinical CYP2C9 assays

AMP offers recommendations to aid in design and validation of clinical CYP2C9 assays

Access to real-time genotype data influences prescriber behavior after PCI

Access to real-time genotype data influences prescriber behavior after PCI

Experts issue new guidelines for use of genetic testing in psychiatric care

Experts issue new guidelines for use of genetic testing in psychiatric care

New collaboration aims to prevent life-threatening adverse reactions to medications

New collaboration aims to prevent life-threatening adverse reactions to medications

FDA permits marketing of 23andme Personal Genome Service Pharmacogenetic Reports test

FDA permits marketing of 23andme Personal Genome Service Pharmacogenetic Reports test

Beyond BRCA: Epigenetic Silencing in Breast Cancer

Beyond BRCA: Epigenetic Silencing in Breast Cancer

Study highlights need for population-specific precision medicine programs in Latin America

Study highlights need for population-specific precision medicine programs in Latin America

Easy and inexpensive test could one day help guide epilepsy treatment

Easy and inexpensive test could one day help guide epilepsy treatment

Genetic variant discovery could improve safety, effectiveness of drugs for asthma and COPD

Genetic variant discovery could improve safety, effectiveness of drugs for asthma and COPD

Medical University of Vienna to partner with bio.logis GIM in pharmacogenetics

Medical University of Vienna to partner with bio.logis GIM in pharmacogenetics

New clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy

New clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy

Medicare fails to recover hundreds of millions of dollars in lab overcharges

Medicare fails to recover hundreds of millions of dollars in lab overcharges

MTSA expands efforts to fight against national opioid epidemic

MTSA expands efforts to fight against national opioid epidemic

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

LimTox online software tool provides information on drug hepatotoxicity

LimTox online software tool provides information on drug hepatotoxicity

Study identifies potential link between genes and treatment response in children with CAE

Study identifies potential link between genes and treatment response in children with CAE

Alzheimer's drug prescribed off-label could accelerate cognitive decline for some patients

Alzheimer's drug prescribed off-label could accelerate cognitive decline for some patients

Researchers develop new tool to help avoid adverse reactions to drugs

Researchers develop new tool to help avoid adverse reactions to drugs