Phenotype News and Research

RSS

Researchers find 'origin' of cancer spread

The discovery of the cell, which they are calling 'the cell of origin' sheds new light on what fuels cancer growth and how to potentially stop it.

4 Feb 2019

Study sheds light on the genetic causes of tumors in salivary glands

Acinic cell carcinoma is the third most common malignant form of salivary gland cancer. These tumors are similar to normal salivary gland tissue and occur most frequently in the parotid gland.

31 Jan 2019

New autism mouse model shows how epigenetic regulation impacts downstream gene

The causes of autism spectrum disorder are diverse and to some extent, unknown. But without doubt, they are complex, layered and deeply nuanced.

31 Jan 2019

Study shows that aging and chronic diseases share common genetic factors

The global population aged 60 or over is growing faster than all younger age groups and faces the tide of chronic diseases threatening their quality of life and posing challenges to healthcare and economy systems.

30 Jan 2019

Big data opens door for characterizing immunity-related genome in Japanese population

Although different genes are distributed widely across chromosomes, many genes related to the immune system are clustered together on human chromosome 6, in a segment called the major histocompatibility complex (MHC) region.

29 Jan 2019

NIH grants awarded to Nanoscope to recruit talent and develop optogenetic delivery platforms

Retinal dystrophies such as Age-related macular degeneration (AMD) are a major cause of vision loss in aging populations. National Eye Institute (NEI) estimates that the prevalence of advanced AMD will grow to nearly 3 million by 2020.

29 Jan 2019

Study: CD4+ T cells could be important mediators of protection against Zika virus

Immune cells called CD4+ T cells could be important mediators of protection against the Zika virus, according to a study published January 24 in the open-access journal PLOS Pathogens by Sujan Shresta of the La Jolla Institute for Allergy and Immunology, and colleagues.

25 Jan 2019

Understanding healing role for kidney-resident macrophages may help treat acute kidney injury

During development in the womb, immune cells called macrophages go to the kidneys, and they remain there for life. Understanding the possible healing role for these macrophages after kidney damage may be crucial to helping treat patients who suffer acute kidney injury.

25 Jan 2019

Study determines impact of antibiotic perturbation of the gut microbiome on skeletal health

Microbes are often seen as pathogens that cause disease and antibiotics have been used successfully to combat these foreign invaders. In reality, the picture is more complex.

17 Jan 2019

Unconventional T cells may account for failure of IL-17 inhibition in rheumatoid arthritis

Spondyloarthritis is one of the most common types of chronic joint inflammation affecting nearly 1-2% of the Western population.

10 Jan 2019

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Millions of people suffer from inflammatory bowel disease worldwide, either in the form of ulcerative colitis or Crohn's disease, and few effective long-term treatments are available. Chronic intestinal inflammation is a hallmark of IBD.

9 Jan 2019

Study shows how specific mutations in SYNE1 gene may increase bipolar disorder risk

A new study by researchers at The Picower Institute for Learning and Memory at MIT finds that the protein CPG2 is significantly less abundant in the brains of people with bipolar disorder and shows how specific mutations in the SYNE1 gene that encodes the protein undermine its expression and its function in neurons.

9 Jan 2019

Heberden's nodes may be associated with knee osteoarthritis

Heberden's nodes are bony enlargements of the finger joints that are readily detectable in a routine physical exam and are considered hallmarks of osteoarthritis. A new Arthritis & Rheumatology study found that the presence of HNs may also indicate structural damage associated with knee osteoarthritis.

9 Jan 2019

Study: Mice lacking PARL protein display specific problems in the nervous system reminiscent of Leigh syndrome

Leuven researchers led by professor Bart De Strooper (VIB-KU Leuven) have identified a new role for PARL, a protein that has been linked to Parkinson's disease.

3 Jan 2019

Researchers launch clinical trial to develop breath test for multiple cancers

Researchers have launched a clinical trial to develop a breath test, analyzing molecules that could indicate the presence of cancer at an early stage.

2 Jan 2019

New editorial proposes changes to improve minority representation in clinical trials

In an editorial published in CNS Spectrums, Jay Avasarala, MD, PhD, takes the research community to task for its lack of minority representation in Phase III clinical trials for drugs to treat Multiple Sclerosis (MS).

2 Jan 2019

WU biomedical engineer makes a significant step toward precision medicine

In 2015, then President Barack Obama launched a precision medicine initiative, saying that its promise was "delivering the right treatments, at the right time, every time to the right person.

20 Dec 2018

Researchers identify link between mucus in the small airways and pulmonary fibrosis

A team of investigators led by members of the University of Colorado School of Medicine faculty at CU Anschutz Medical Campus has identified a connection between mucus in the small airways and pulmonary fibrosis.

18 Dec 2018

Answering the Biggest Neurological Research Questions of Today

An interview with Dr. Peggy Taylor, discussing the biggest neurological research questions of today and how BioLegend is helping to develop new biomarkers for neurological disease.

From BioLegend 14 Dec 2018

UAB research may point a path to more effective influenza vaccines

Seasonal influenza vaccines are typically less than 50 percent effective, according to Centers for Disease Control and Prevention studies. Research at the University of Alabama at Birmingham, published this week in Nature Immunology, may point a path to more effective vaccines.

6 Dec 2018

Phenotype News and Research

Researchers find 'origin' of cancer spread

Study sheds light on the genetic causes of tumors in salivary glands

New autism mouse model shows how epigenetic regulation impacts downstream gene

Study shows that aging and chronic diseases share common genetic factors

Big data opens door for characterizing immunity-related genome in Japanese population

NIH grants awarded to Nanoscope to recruit talent and develop optogenetic delivery platforms

Study: CD4+ T cells could be important mediators of protection against Zika virus

Understanding healing role for kidney-resident macrophages may help treat acute kidney injury

Study determines impact of antibiotic perturbation of the gut microbiome on skeletal health

Unconventional T cells may account for failure of IL-17 inhibition in rheumatoid arthritis

Metabolite from berries and pomegranates can mitigate inflammatory bowel disease

Study shows how specific mutations in SYNE1 gene may increase bipolar disorder risk

Heberden's nodes may be associated with knee osteoarthritis

Study: Mice lacking PARL protein display specific problems in the nervous system reminiscent of Leigh syndrome

Researchers launch clinical trial to develop breath test for multiple cancers

New editorial proposes changes to improve minority representation in clinical trials

WU biomedical engineer makes a significant step toward precision medicine

Researchers identify link between mucus in the small airways and pulmonary fibrosis

Answering the Biggest Neurological Research Questions of Today

UAB research may point a path to more effective influenza vaccines

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News