Phenotype News and Research

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Researchers discover what makes lymphomas tick

University of Pennsylvania researchers and their colleagues at the Wistar Institute and University of Oxford have discovered the molecular process by which the PAX5 protein, necessary for lymphocyte development, promotes the growth of common lymphomas, thereby unveiling a potential new target in the fight against cancer.

30 Aug 2007

Antioxidant overload

Despite the popular notion that antioxidants, such as vitamins C and E, offer health-promoting benefits by protecting against damaging free radicals, a new study in the August 10 issue of the journal Cell reveals that, in fact, balance is the key.

12 Aug 2007

Sex steroids, platelet aggregation and inflammation

In women, hormone therapy is a risk factor for venous thrombosis, a blood clot forming deep inside the vein. Despite the fact that the disorder is rare, it increases exponentially during menopause and can be deadly.

11 Aug 2007

New approach to assessing clot risk in menopausal women

In women, hormone therapy is a risk factor for venous thrombosis, a blood clot forming deep inside the vein.

9 Aug 2007

E. coli bacteria linked to Crohn's disease

A team of Cornell University scientists from the College of Veterinary Medicine, Weill Cornell Medical College and the College of Agriculture and Life Sciences have discovered that a novel group of E. coli bacteria, containing genes similar to those described in uropathogenic and avian pathogenic E. coli and enteropathogenic bacteria such as salmonella, cholera, bubonic plague, is associated with intestinal inflammation in patients with Crohn's disease in their research paper published July 12 by the ISME Journal: Multidisciplinary Journal of Microbial Ecology.

8 Aug 2007

Variant of the dopamine receptor gene may be associated with ADHD

A variant of the dopamine receptor gene may be associated with attention-deficit/hyperactivity disorder (ADHD) and with thinner tissue in areas of the brain that handle attention, but also appears associated with better clinical outcomes among individuals with the disorder, according to a report in the August issue of Archives of General Psychiatry , one of the JAMA/Archives journals.

7 Aug 2007

Scientists make female mice act blokey!

By short-circuiting the sensory organ that detects the chemical cues mice use to attract mates, a team of Howard Hughes Medical Institute (HHMI) researchers has prompted female mice to behave like male mice in the throes of courtship.

6 Aug 2007

Sex and gender differences in chronic obstructive pulmonary disease

In the first study to directly compare men and women with chronic obstructive pulmonary disease, or COPD, and severe emphysema, researchers have found that there are marked differences between the sexes.

3 Aug 2007

New approach for restless legs syndrome

Scientists at deCODE genetics ( NASDAQ:DCGN ) in collaboration with colleagues from Emory University today report the discovery of the first variant in the sequence of the human genome ever linked to risk of Restless Legs Syndrome (RLS) and Periodic Limb Movements (PLMs).

19 Jul 2007

New method to estimate sickle cell disease severity

Researchers from Boston University School of Medicine (BUSM) and Boston University School of Public Health (BUSPH) have developed a method to estimate sickle cell disease severity and predict the risk of death in people with this disease.

12 Jul 2007

New model of early biological evolution

In a study publishing in PLoS Computational Biology, Shakhnovich et al present a new model of early biological evolution , the first that directly relates the fitness of a population of evolving model organisms to the properties of their proteins.

12 Jul 2007

Many of the areas of the human genome previously thought to be deserts are in fact teeming with life

Most known human genes in the genome map are still incompletely annotated, says Professor Alexandre Reymond, from the Centre for Integrative Genomics, University of Lausanne, Switzerland and the Department of Genetic Medicine, University of Geneva, Geneva, Switzerland.

19 Jun 2007

Focus on motor neurone disease

Motor neurone disease (MND), also known as amyotrophic lateral sclerosis, is a degenerative disease of unknown cause which causes patients to lose basic motor functions and has a devastating effect on them and their families.

17 Jun 2007

Injected neural stem cells reduce Parkinson's symptoms in primates

Primates with severe Parkinson's disease were able to walk, move, and eat better, and had diminished tremors after being injected with human neural stem cells, a research team from Yale, Harvard, the University of Colorado, and the Burnham Institute report in Proceedings of the National Academy of Sciences.

14 Jun 2007

Phenotype News and Research

Researchers discover what makes lymphomas tick

Antioxidant overload

Sex steroids, platelet aggregation and inflammation

New approach to assessing clot risk in menopausal women

E. coli bacteria linked to Crohn's disease

Variant of the dopamine receptor gene may be associated with ADHD

Scientists make female mice act blokey!

Sex and gender differences in chronic obstructive pulmonary disease

New approach for restless legs syndrome

New method to estimate sickle cell disease severity

New model of early biological evolution

Many of the areas of the human genome previously thought to be deserts are in fact teeming with life

Focus on motor neurone disease

Injected neural stem cells reduce Parkinson's symptoms in primates

Researchers shed light on congenital diaphragmatic hernia

New regulator of fat metabolism identified

Systems characterization of cell surface receptors

New discoveries on genes implicated in Fanconi anaemia

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients

New form of idiopathic pulmonary fibrosis found

One Health, One Mission: The World Organisation for Animal Health on the AMR Frontline

Uniting Against Resistance: The World Health Organization for World Antimicrobial Awareness Week 2023

Tackling Antimicrobial Resistance: A Conversation with Dr. Beverley Isherwood

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