Pituitary Gland News and Research

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New molecular evidence of the role of the hormone prolactin in breast cancer

They have found that prolactin, a pituitary hormone that normally stimulates breast development and milk production, initiates a new “signaling pathway” that may regulate the growth and survival of breast cancer cells.

29 Sep 2007

Exercise might actually increase the risk of developing ovarian cancer

Barcelona, Spain: A new study adds fuel to the debate over whether being fat or inactive affects the risk of developing ovarian cancer.

27 Sep 2007

Low birth weight children may be at a greater risk of stress-related health problems as adults

Findings from this study show that low birth weight (below the 10th percentile) can lead later in life to low concentrations of cortisol, a hormone that regulates stress response by adjusting blood pressure and blood sugar levels.

27 Sep 2007

FDA approves Somatuline Depot to treat acromegaly

The U.S. Food and Drug Administration has approved Somatuline Depot (lanreotide acetate injection) for the treatment of acromegaly, a rare and potentially life threatening disease in adults caused by abnormal secretion of growth hormone (GH), commonly from a benign tumor located in the pituitary gland located in the brain.

30 Aug 2007

Sildenafil increases release of key reproductive hormone oxytocin

Researchers at the University of Wisconsin-Madison report this month that sildenafil increases the amount of oxytocin released by stimulation of the posterior pituitary gland, a small structure directly underneath the brain that regulates hormone levels in response to neural signals.

24 Aug 2007

Researchers improve accuracy of thyroid hormone testing

Researchers at Georgetown University Medical Center have developed a fast and accurate way to measure a major hormone released by the thyroid gland--an advance they say may help in the treatment of many women who have overactive or underactive thyroid glands.

26 Jul 2007

Hormone treatment could cut need for chemo in some younger breast cancer patients

Around 5,500 pre-menopausal breast cancer patients could be offered a hormone drug that is shown to be as effective as traditional chemotherapy - and so avoid potential infertility and long-term menopausal side effects - according to a Cancer Research UK report published in The Lancet.

20 May 2007

The circadian rhythm of glucocorticoids is regulated by a gating mechanism residing in the adrenal cortical clock

In mammals, including humans, a master clock in the brain and subordinate clocks found in organs throughout the body coordinate daily, or circadian, rhythms of behavior and physiology.

8 Aug 2006

New hope for women with Alzheimer's disease

Leuprolide acetate helps women with mild-to-moderate Alzheimer's disease maintain functional capabilities for a longer period of time, according to data presented Monday by Voyager Pharmaceutical Corporation.

18 Jul 2006

Osteoporosis could be caused by factors other than declining estrogen levels

New evidence in the April 21, 2006 Cell challenges the long-standing notion that declining estrogen levels alone lead to osteoporosis after women go through menopause. The researchers rather found that high levels of pituitary-derived follicle-stimulating hormone (FSH) cause bone loss in mice. The pituitary is a master gland found at the base of the brain.

26 Apr 2006

Scientists find that growth hormone is produced in the brain

Scientists have found that growth hormone, a substance that is used for body growth, is produced in the brain, according to an article published in the Proceedings of the National Academy of Sciences.

11 Apr 2006

Hormone discovered in bird brains also plays major role in mammalian reproductive system

University of California, Berkeley, researchers have discovered a new actor in the mammalian reproductive system, a hormone that fills a role long suspected, but until now undetected.

7 Feb 2006

rhTSH combined with radiation therapy successfully destroys remaining thyroid tissue

A multicenter international study, including Johns Hopkins, has found that after surgery for thyroid cancer, giving genetically engineered human thyroid-stimulating hormone (rhTSH) before radioiodine treatment avoids the previous need to stop thyroid replacement therapy and the miserable side effects that go with it.

9 Jan 2006

Stress increases alcoholism

A number of sociocultural studies indicate that stress may increase the risk of alcoholism. In other words, an individual's ability to cope with stressful situations may indicate his or her vulnerability to alcoholism.

13 Dec 2005

First step in exploring the GnRH reproduction-related circuitry in the brain

Howard Hughes Medical Institute researchers have discovered a vast network of neurons in the brain of mice that governs reproduction and controls the effects of reproductive status on other brain functions.

14 Nov 2005

Search for genes responsible for anxiety disorders

Increasing the activity of two enzymes better known for their role in oxidative stress metabolism turns normally relaxed mice into "Nervous Nellies," according to research conducted at the Salk Institute for Biological Studies and reported in the early online edition of Nature.

30 Oct 2005

Growth hormone illegal for off-label anti-aging use

Because of 1988 and 1990 amendments to the Food, Drug and Cosmetic Act, off-label distribution or provision of human growth hormone to treat aging or age-associated illnesses is illegal in the United States, according to a report in the Journal of the American Medical Association.

25 Oct 2005

Increlex - first major innovation in 20 years for the treatment of growth failure

Rush University Medical Center is participating in a clinical trial to evaluate the potential benefit of the first major innovation in 20 years for the treatment of growth failure.

26 Sep 2005

Blood test to measure hormone prolactin can help determine type of seizure

Using a blood test to measure the level of the hormone prolactin can help determine, in certain clinical settings, whether an epileptic seizure has occurred, according to a guideline developed by the American Academy of Neurology and published in the September 13, 2005 issue of Neurology.

20 Sep 2005

Mission to teach patients about modern treatments for sinusitis

Coughing, headaches, fatigue, post-nasal drip and intense pressure throughout the face. For millions of Americans, these aren't just the side effects of a short bout with the flu, but what they experience every day living with sinusitis.

16 Aug 2005