Pituitary Gland News and Research

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CNS experts create new research-based guidelines for evaluation and treatment of NFPAs

Nonfunctioning pituitary adenomas (NFPAs) are common benign tumors that may be present for years before causing any symptoms.

26 Sep 2016

Taking ipilimumab, nivolumab drugs may increase risk of developing rheumatologic diseases

Case reports on 13 cancer patients suggest that a small number of cancer patients taking the immunotherapy drugs ipilimumab and nivolumab may be at some higher-than-normal risk of developing autoimmune joint and tissue diseases, including inflammatory arthritis, according to a preliminary study by Johns Hopkins Medicine researchers.

24 Jun 2016

Proton therapy offers new hope to patients with inoperable tumors

An enormous high tech machine is providing new hope to patients across the country with inoperable tumors. Proton therapy is a precise radiation technique that reduces the side effects often accompanied by traditional treatment options. Thanks to this remarkable technology, a new proton therapy center at UF Health Cancer Center - Orlando Health is saving the eyesight of a new mother who was diagnosed with a tumor behind her eye during her second trimester of pregnancy.

5 May 2016

Blast-related concussions result in hormone changes that lead to poor quality of life among veterans

A study in military veterans finds that explosive blast-related concussions frequently result in hormone changes leading to problems such as sleep disturbances, fatigue, depression and poor quality of life. The research, to be presented Saturday at the Endocrine Society's 98th annual meeting in Boston, evaluated hormone levels in 41 male veterans who had been deployed to Iraq or Afghanistan.

4 Apr 2016

David Calligaris wins ABC Best Paper Award

David Calligaris is the winner of this year's ABC Best Paper Award, presented by the Springer journal Analytical and Bioanalytical Chemistry. In a paper published in ABC, lead author Calligaris and his colleagues describe a novel system using mass spectrometry as an intraoperative tool. Their method opens new possibilities to detect additional tumour markers which are useful in diagnosing brain and breast tumours during surgery.

11 Feb 2016

Proton radiotherapy as effective as standard photon therapy in treating pediatric brain tumor

The use of proton radiotherapy to treat the most common malignant brain tumor in children is as effective as standard photon (x-ray) radiation therapy while causing fewer long-term side effects such as hearing loss and cognitive disorders, according to a study receiving online publication in Lancet Oncology.

30 Jan 2016

BioTE Medical Combat Trauma Treatment Study shows promising results in veterans with PTSD and TBI

A current BioTE Medical Combat Trauma Treatment Study (in conjunction with the Veterans Advocacy Center (VAC)) is showing promising results in helping veterans suffering from Post-Traumatic Stress Disorder (PTSD) and Traumatic Brain Injury (TBI).

31 Dec 2015

Multiple small doses of targeted radiation therapy more effective at destroying pituitary gland tumors

A recent patient study at Houston Methodist Hospital proved that multiple small doses of highly focused radiation therapy is safer and more effective than a single larger dose of radiation at destroying pituitary gland tumors.

18 Dec 2015

More hormone treatments decrease women's chances of having baby

A Michigan State University study has found that too much of a hormone commonly used during in vitro fertility, or IVF, treatments actually decreases a woman's chances of having a baby.

24 Nov 2015

IU researchers discover hormonal mechanism that links short winter days with increased aggression in females

Indiana University researchers have discovered a hormonal mechanism in hamsters that connects short winter days with increased aggression in females, and that it differs from the mechanism that controls this same response in males.

18 Nov 2015

Study explores effectiveness of frontline treatments for couples with unexplained infertility

A breast cancer drug with promise for improving the chance that couples with unexplained infertility can have a baby without increasing their risk of multiple births apparently does not deliver, according to a comparative study.

24 Sep 2015

Research: Cancer preventative surgery may not be necessary in the future

Surgery to remove the breasts of women at increased risk of developing breast cancer may not be necessary in the future, according to research published in EBioMedicine. Two new studies looking at the effect the menstrual cycle has on the development of breast and ovarian cancer reveal alternative prevention strategies that may render surgery unnecessary.

11 Sep 2015

A new approach to prevent breast and ovarian cancer

Surgery to remove the breasts of women at increased risk of developing breast cancer may not be necessary in the future, according to research published in EBioMedicine.

10 Sep 2015

New genome-wide association study sheds light on the underlying biology of polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) has been passed down in many families for generations -- causing reproductive and metabolic health problems for millions of women around the world. Yet, its cause remains unknown despite more than 80 years of research since the disorder was first described in 1935.

20 Aug 2015

FDA accepts Chiasma's NDA filing for octreotide capsules for treatment of adult patients with acromegaly

Chiasma, Inc., a U.S. late-stage biopharmaceutical company, today announced that the U.S. Food and Drug Administration has accepted for filing the Company's New Drug Application (NDA) for the marketing and sale of octreotide capsules, an oral drug proposed for the maintenance therapy of adult patients with acromegaly.

17 Aug 2015

Endocrine Society recommends removal of tumor as first-line treatment for endogenous Cushing's syndrome

The Endocrine Society today issued a Clinical Practice Guideline (CPG) on strategies for treating Cushing's syndrome, a condition caused by overexposure to the hormone cortisol.

30 Jul 2015

Vanderbilt researchers hope to give new dexterity to needlescopic surgery with tiny mechanical wrist

With the flick of a tiny mechanical wrist, a team of engineers and doctors at Vanderbilt University's Medical Engineering and Discovery Laboratory hope to give needlescopic surgery a whole new degree of dexterity.

24 Jul 2015

Aeterna Zentaris selects Ergomed to manage Phase 3 clinical study of Macrilen

Aeterna Zentaris Inc. announced today that it has executed a definitive agreement with Ergomed PLC, pursuant to which Ergomed will manage the new, confirmatory Phase 3 clinical study to demonstrate the efficacy of Macrilen (macimorelin), a novel orally-active ghrelin agonist for use in evaluating adult growth hormone deficiency ("AGHD").

25 Jun 2015

Aeterna Zentaris plans to conduct Macrilen Phase 3 clinical study for AGHD

Aeterna Zentaris Inc. today announced plans to conduct a new, confirmatory Phase 3 clinical study to demonstrate the efficacy of Macrilen (macimorelin), a novel orally-active ghrelin agonist for use in evaluating adult growth hormone deficiency ("AGHD"), as well as a dedicated thorough QT study to evaluate the effect of Macrilen on myocardial repolarization.

13 Apr 2015

Letrozole helps restore fertility in obese, infertile men

A letrozole pill once a week restored fertility in obese, infertile men and led to their partners giving birth to two full-term, healthy babies, according to a new study from Canada. The results will be presented Thursday at the Endocrine Society's 97th annual meeting in San Diego.

9 Mar 2015