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GlaxoSmithKline starts phase III trial of Syncria (albiglutide) type 2 diabetes medication

GlaxoSmithKline has announced initiation and dosing of the first patient of the Phase III clinical trial programme to evaluate the efficacy, safety and tolerability of the investigational GLP-1 (Glucagon-like peptide 1) agonist Syncria (albiglutide) in men and women with type 2 diabetes.

18 Feb 2009

Asthma drugs need to be maintained for continued benefit

Children whose asthma improved while taking steroid drugs for several years did not see those improvements continue after stopping the drugs, new results from a comprehensive childhood asthma study show.

18 Feb 2009

New nationwide Alzheimer's study underway

Researchers at Wake Forest University Baptist Medical Center are preparing to begin a clinical trial aimed at testing an investigational new drug that may help control the progression of Alzheimer's disease.

17 Feb 2009

Experimental antiarrhythmic drug dronedarone reduces death rate in patients with atrial fibrillation

Results from the ATHENA trial, reported in the 12th February issue of the New England Journal of Medicine , suggest that the (as yet unlicensed) antiarrhythmic drug dronedarone can reduce the incidence of cardiovascular-related hospitalisation or death in patients with atrial fibrillation.

16 Feb 2009

Avosentan shows prmoise for diabetic kidney disease

A new drug called avosentan significantly lowers urinary protein excretion-an important marker of kidney disease progression-in patients with diabetic kidney disease, according to an international clinical trial appearing in the March 2009 issue of the Journal of the American Society Nephrology (JASN).

16 Feb 2009

Study on ustekinumab for treatment of psoriatic arthritis published

A group of patients suffering from potentially debilitating psoriatic arthritis showed significant and prolonged improvement after treatment with ustekinumab, according to data from a randomized, double-blind, placebo-controlled study in patients with moderate to severe psoriatic arthritis (PsA).

11 Feb 2009

ViroPharma reports results of trial for Maribavir in bone marrow transplant patients

ViroPharma Incorporated has announced that its Phase 3 trial evaluating maribavir used as prophylaxis in allogeneic stem cell, or bone marrow, transplant (SCT) patients did not achieve its primary endpoint.

10 Feb 2009

Nightly dose of vitamin B12 an effective canker sore therapy

A team of physicians at Ben-Gurion University of the Negev has discovered that a nightly dose of vitamin B12 is a simple, effective and low risk therapy to prevent Recurrent Aphthous Stomatitis (RAS), better known as "canker sores."

10 Feb 2009

Long-term use of inhaled corticosteroid drugs increases risk of pneumonia for COPD patients

Newly published research out of Wake Forest University School of Medicine finds that a popular class of anti-inflammatory inhalers significantly increases the risk of pneumonia in patients with Chronic Obstructive Pulmonary Disease (COPD).

9 Feb 2009

Anti-HIV vaginal gel shows promise

An investigational vaginal gel intended to prevent HIV infection in women has demonstrated encouraging signs of success in a clinical trial conducted in Africa and the United States.

9 Feb 2009

Idenix Pharmaceuticals and GSK sign agreement for novel NNRTI for treatment of HIV

Idenix Pharmaceuticals, Inc. and GlaxoSmithKline (GSK) today announced the execution of a license agreement granting GSK exclusive worldwide rights to IDX899.

8 Feb 2009

Aspirin cuts stomach cancer risk

Aspirin users could be 36 per cent less likely to get a type of stomach cancer, according to a study published in the British Journal of Cancer.

8 Feb 2009

Study tests salsalate anti-inflammatory for poorly controlled type 2 diabetes

Researchers in 20 medical centers across the country are enrolling adults with type 2 diabetes who have poorly controlled blood glucose to participate in a clinical study, Targeting Inflammation with Salsalate in Type 2 Diabetes (TINSAL-T2D).

5 Feb 2009

Safinamide significantly improved motor function in patients with advanced Parkinson's disease

Merck Serono, a division of Merck KGaA, Darmstadt, Germany, and its partner Newron Pharmaceuticals SpA has announced that the first Phase III trial of investigational agent safinamide as adjunctive therapy to levodopa (study 016) met its primary endpoint by increasing daily "ON" time in mid- to late-stage Parkinson's disease patients with motor fluctuations by 1.3 hours.

5 Feb 2009

FDA grants priority review of Cinryze C1 inhibitor as treatment for acute attacks of hereditary angioedema

ViroPharma Incorporated has announced that the U.S. Food and Drug Administration (FDA) has granted priority review for Cinryze C1 Inhibitor (human) as a treatment for acute attacks of Hereditary Angioedema (HAE).

5 Feb 2009

Infliximab after intestinal resective surgery may help prevent post-op Crohn's disease recurrence

The administration of infliximab after intestinal resective surgery was found to be effective at preventing endoscopic and histological recurrence of Crohn's disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

2 Feb 2009

Study looks at acupuncture for pain

The pain relieving effects of acupuncture compared with placebo are small and seem to lack clinical relevance, according to a study published on bmj.com.

29 Jan 2009

New bone cement may prevent amputations

Old technologies, bone cement and a well known antibiotic, may effectively fight an emerging infection in soldiers with compound bone fractures, according to a study published online in the Journal of Orthopedic Research.

29 Jan 2009

Study of cannabinoid medicine for pain found patients got 'high,' but effects not related to pain relief

Researchers at Brigham and Women's Hospital found that patients taking cannabinoid medicines for pain may be getting "high," but these effects were unrelated to relief from their pain symptoms. Results of their study, one of the first to examine the addictive potential of this class of pain medicine, were presented today at the American Academy of Pain Medicine's 25th Annual Meeting.

29 Jan 2009

Early treatment with rasagiline (Azilect) for Parkinson's best

There is hope that the drug rasagiline can do what no other medication for Parkinson's disease now does -- slow the progression of a devastating degenerative brain disease that eventually robs people of their ability to move and function.

27 Jan 2009

Placebo News and Research

GlaxoSmithKline starts phase III trial of Syncria (albiglutide) type 2 diabetes medication

Asthma drugs need to be maintained for continued benefit

New nationwide Alzheimer's study underway

Experimental antiarrhythmic drug dronedarone reduces death rate in patients with atrial fibrillation

Avosentan shows prmoise for diabetic kidney disease

Study on ustekinumab for treatment of psoriatic arthritis published

ViroPharma reports results of trial for Maribavir in bone marrow transplant patients

Nightly dose of vitamin B12 an effective canker sore therapy

Long-term use of inhaled corticosteroid drugs increases risk of pneumonia for COPD patients

Anti-HIV vaginal gel shows promise

Idenix Pharmaceuticals and GSK sign agreement for novel NNRTI for treatment of HIV

Aspirin cuts stomach cancer risk

Study tests salsalate anti-inflammatory for poorly controlled type 2 diabetes

Safinamide significantly improved motor function in patients with advanced Parkinson's disease

FDA grants priority review of Cinryze C1 inhibitor as treatment for acute attacks of hereditary angioedema

Infliximab after intestinal resective surgery may help prevent post-op Crohn's disease recurrence

Study looks at acupuncture for pain

New bone cement may prevent amputations

Study of cannabinoid medicine for pain found patients got 'high,' but effects not related to pain relief

Early treatment with rasagiline (Azilect) for Parkinson's best

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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