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Single dose of malaria monoclonal antibody 77% effective in children, trial in Mali shows

One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country's six-month malaria season, according to the results of a mid-stage clinical trial.

26 Apr 2024

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function.

26 Apr 2024

Exploring the potential of ketogenic diets in managing epilepsy

The mechanisms of action, efficacy, and side effects of ketogenic diet (KD) variations in epileptic patients.

26 Apr 2024

Advancing medical treatment with causal machine learning

Machines can learn not only to make predictions, but also to handle causal relationships. An international research team shows how this could make therapies safer, more efficient, and more individualized.

25 Apr 2024

Monoclonal antibody Prasinezumab shows promise in slowing rapid Parkinson's progression

A recent study in Nature Medicine evaluated the efficacy of prasinezumab, a monoclonal antibody, in slowing the progression of motor symptoms in Parkinson’s disease patients with rapidly progressing forms, using phase II clinical trial data.

19 Apr 2024

Phase 2 trial reveals Lixisenatide may reduce motor disability in Parkinson’s patients

A trial of lixisenatide to assess its effects in early Parkinson’s disease.

18 Apr 2024

Exploring the benefits of blueberries: Studies link extract to reduced cognitive aging

Wild blueberry extracts (WBE) may improve cognitive performance.

18 Apr 2024

Phase 3 trial shows overall survival benefit from adjuvant therapy in kidney cancer patients

For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.

17 Apr 2024

Study finds microdosing LSD leads to longer sleep: Insights from a controlled trial

A phase I trial to assess the effect of micro-dosing of lysergic acid diethylamide (LSD) on the sleep.

17 Apr 2024

Managing diabetes with probiotics and synbiotics

Systematic review in Clinical Nutrition analyzed randomized trials to assess the impact of prebiotics and synbiotics on glycemic control in diabetes, revealing significant benefits in fasting glucose, serum insulin, and HbA1C levels.

16 Apr 2024

Study shows potential for universal flu vaccine with broad antibody response

Study discusses the potential of universal influenza vaccines, emphasizing the importance of antibody breadth and Fc receptor (FcR) effector functions in protecting against various influenza strains, including those with pandemic potential.

15 Apr 2024

Roasted green tea boosts mental task performance, study finds

Study examines how the consumption of green tea and roasted green tea affects human responses during mental tasks, demonstrating that roasted green tea can enhance performance and reduce fatigue.

15 Apr 2024

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Low-dose esketamine administered post-labor significantly reduced depressive symptoms in women with prenatal depression within 42 days, despite an increase in short-lived neuropsychiatric side effects.

14 Apr 2024

Cannabis compound d-limonene reduces anxiety-inducing effects of THC

A Johns Hopkins Medicine-led research team has added to evidence that a chemical found naturally in cannabis (also known as marijuana) can -; in the right amounts -; lessen the anxiety-inducing effects of tetrahydrocannabinol (THC), the primary psychoactive sister chemical found in cannabis.

12 Apr 2024

Low dose esketamine injection after childbirth reduces postpartum depression

A single low dose injection of esketamine given immediately after childbirth reduces major depressive episodes in individuals with depressive symptoms during pregnancy (prenatal depression), finds a clinical trial published by The BMJ today.

12 Apr 2024

Transcranial direct current stimulation shows promise for treating depression, anxiety in older adults

A noninvasive brain stimulation treatment improved depression and anxiety symptoms among older adults in a new University of Florida-led study.

12 Apr 2024

New sleep-enhancing nutraceutical blend falls short in clinical trial

Study investigates the impact of a unique nutraceutical blend, combining L-theanine with valerian, saffron, and lemon balm extracts, on improving sleep quality, finding no significant difference compared to a placebo in individuals experiencing poor sleep.

10 Apr 2024

New natural supplement shows promise in preventing postpartum blues

A new study published in the Lancet discovery science journal eClinicalMedicine has confirmed that a novel natural supplement-;invented, researched, developed and commercialized at the Centre for Addiction and Mental Health (CAMH)-;prevents postpartum blues, and reduces symptoms of postpartum depression over the following six months after giving birth.

10 Apr 2024

Probiotics plus vitamin D supplements may improve cognitive function in individuals with schizophrenia

Previous studies have questioned whether gut microbe imbalances and vitamin D deficiency may be linked to schizophrenia.

10 Apr 2024

SGLT2 inhibitors: A game-changer in preventing heart failure and sudden cardiac deaths

study reveals that SGLT2 inhibitors consistently lower the risk of major adverse cardiovascular events by 9% across various patient groups, especially impacting cardiovascular death reduction, highlighting their broad therapeutic potential beyond diabetes management.

9 Apr 2024

Placebo News and Research

Single dose of malaria monoclonal antibody 77% effective in children, trial in Mali shows

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Exploring the potential of ketogenic diets in managing epilepsy

Advancing medical treatment with causal machine learning

Monoclonal antibody Prasinezumab shows promise in slowing rapid Parkinson's progression

Phase 2 trial reveals Lixisenatide may reduce motor disability in Parkinson’s patients

Exploring the benefits of blueberries: Studies link extract to reduced cognitive aging

Phase 3 trial shows overall survival benefit from adjuvant therapy in kidney cancer patients

Study finds microdosing LSD leads to longer sleep: Insights from a controlled trial

Managing diabetes with probiotics and synbiotics

Study shows potential for universal flu vaccine with broad antibody response

Roasted green tea boosts mental task performance, study finds

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Cannabis compound d-limonene reduces anxiety-inducing effects of THC

Low dose esketamine injection after childbirth reduces postpartum depression

Transcranial direct current stimulation shows promise for treating depression, anxiety in older adults

New sleep-enhancing nutraceutical blend falls short in clinical trial

New natural supplement shows promise in preventing postpartum blues

Probiotics plus vitamin D supplements may improve cognitive function in individuals with schizophrenia

SGLT2 inhibitors: A game-changer in preventing heart failure and sudden cardiac deaths

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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