Placebo News and Research

RSS

FDA wants new warnings on antidepressant medications

The U.S. Food and Drug Administration (FDA) has proposed that makers of all antidepressant medications update the existing black box warning on their products' labeling to include warnings about increased risks of suicidal thinking and behavior, known as suicidality, in young adults ages 18 to 24 during initial treatment (generally the first one to two months).

4 May 2007

Statins reduce risk of stroke and heart attack

People whose cholesterol improved after one month on cholesterol-lowering drugs called statins reduced their risk of stroke and heart attack, according to research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 , May 5, 2007.

4 May 2007

BioMarin starts phase 2a study of 6R-BH4 in sickle cell disease

BioMarin Pharmaceutical has announced that the first patient has initiated treatment in the Phase 2a clinical study of 6R-BH4 (sapropterin dihydrochloride) for the treatment of sickle cell disease (SCD).

4 May 2007

Reclast found to cause abnormal heart rhythms

An osteoporosis drug with the potential to cut the risk of spine fractures by 70 percent and the chance of hip fractures by 41 percent, has been found to have an adverse side effect on some women.

3 May 2007

Recommended doses of ginseng, ginko biloba do not interfere with drug absorption

Recent findings that the widely-used herbal supplement Saint John's wort could dramatically affect the absorption and metabolism of many prescription and non-prescription drugs raised concerns that other popular herbal supplements might cause similar changes, thus significantly altering drugs, therapeutic or toxic effects.

2 May 2007

Infliximab fails to improve chronic obstructive pulmonary disease symptoms

A promising anti-inflammatory drug failed to improve symptoms of moderate to severe chronic obstructive pulmonary disease, or COPD, in a large, multi-center trial.

2 May 2007

Adalimumab shows potential for Crohn's disease

A study led by Mayo Clinic found that adalimumab (HUMIRA) is an effective treatment for adults with Crohn's disease who do not respond to infliximab (REMICADE) therapy.

2 May 2007

Rituximab reduces disease activity in multiple sclerosis

A new drug under investigation shows a reduction in disease activity in multiple sclerosis (MS), according to two studies that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston. The drug reduced disease activity as indicated by MRI scans.

2 May 2007

Testosterone cream does not increase sexual drive in female cancer survivors

Increasing the testosterone levels of female cancer survivors using testosterone cream did not improve their libido more than a placebo, according to a randomized controlled clinical trial in the May 2 Journal of the National Cancer Institute.

2 May 2007

Low libido experienced by female cancer survivors is not boosted by testosterone creams

Scientists at the Mayo Clinic College of Medicine in Rochester, Minnesota, say the low libido experienced by many female cancer survivors is not boosted by testosterone creams.

2 May 2007

FDA approves INVEGA treatment for schizophrenia

The U.S. Food and Drug Administration (FDA) has approved INVEGA (paliperidone) Extended-Release Tablets, a new once-daily, atypical antipsychotic, for the long-term maintenance treatment of schizophrenia.

30 Apr 2007

Drug for toenail fungus also blocks angiogenesis

Researchers at Johns Hopkins have discovered to their surprise that a drug commonly used to treat toenail fungus can also block angiogenesis, the growth of new blood vessels commonly seen in cancers.

30 Apr 2007

Heavy use of cannabis triggers psychotic illnesses

Scientists in the UK say the heavy consumption of the drug cannabis may trigger psychotic illnesses such as schizophrenia.

30 Apr 2007

Tarceva extends life of patients with pancreatic cancer

New results published by the Journal of Clinical Oncology show that adding Tarceva (erlotinib) to gemcitabine chemotherapy significantly improves survival by 22 percent in patients with advanced pancreatic cancer.

27 Apr 2007

Sangamo BioSciences starts phase 2 trial of therapy diabetic neuropathy

Sangamo BioSciences has announced that the company has initiated a repeat-dosing, multi-center Phase 2 clinical trial of SB-509 in subjects with moderate to severe diabetic peripheral sensory motor neuropathy (DN).

27 Apr 2007

Taking low dose aspirin does not protect older women against cognitive decline

Identifying ways to prevent dementia is a public health priority. Evidence suggests that aspirin and other anti-inflammatory drugs may protect against dementia, but data from randomised studies to date have been inconclusive.

27 Apr 2007

No evidence to support the use of Dan Shen for ischemic stroke

The herbal medicine Dan Shen, a standard treatment for ischemic stroke in China, lacks strong scientific evidence to support such use, according a new review of studies.

27 Apr 2007

Drugs that adjust dopamine levels in the brain greatly affect how people react to success and failure

In a first-of-its-kind study on humans, researchers measured how dopamine-related drugs affect the striatum, a part of the brain that is stimulated by rewards.

27 Apr 2007

Naproxen and celecoxib do not prevent Alzheimer's disease

Over-the-counter pain medication naproxen and prescription pain reliever celecoxib do not prevent Alzheimer's disease, according to a study published April 25, 2007, in the online edition of Neurology, the scientific journal of the American Academy of Neurology.

26 Apr 2007

ADHD study to look at effects of different stimulant medications and dosages on sleep and mood

Researchers at the University of Illinois at Chicago are comparing two common stimulant drugs with a placebo to evaluate their effect on sleep and behavior in children with attention deficit hyperactivity disorder.

25 Apr 2007