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Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Unlocking clotting mechanisms in caterpillar hemolymph for medical use

Blood is a remarkable material: it must remain fluid inside blood vessels, yet clot as quickly as possible outside them, to stop bleeding. The chemical cascade that makes this possible is well understood for vertebrate blood.

30 Mar 2024

UMass Amherst study targets aplastic anemia with cell retraining approach

Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study that focuses on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the overzealous immune response that can lead to fatal autoimmune disorders.

27 Feb 2024

Gut microbial metabolite plays a role in exacerbating thrombosis

A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis -- the formation of blood clots – researchers report February 23rd in the journal Cell Metabolism.

23 Feb 2024

A high-protein diet and elevation in the amino acid leucine may contribute to buildup of plaque in arteries

Researchers conducted clinical studies on murine animals and humans to evaluate the impact of high protein intake on the amino acid-mammalian target of the rapamycin complex 1 autophagy signaling pathway.

19 Feb 2024

Turning wine waste into wellness: Grape pomace's journey from by-product to superfood

A study in Foods highlights grape pomace's (GP) potential in preventing winery waste, showcasing its bioactive properties for health benefits and applications in food and cosmetics, contributing to sustainable industry practices.

15 Feb 2024

What natural compounds can help you manage your rosacea?

Researchers reviewed existing data on rosacea management using botanicals.

7 Feb 2024

Early whole blood transfusion boosts survival in trauma patients

Significant bleeding due to traumatic injury is the number one cause of preventable deaths in the U.S., with the majority of deaths occurring within six hours.

31 Jan 2024

New research identifies immune system activity as likely cause of long Covid

New research has revealed changes in our blood proteins caused by our body’s own immune defenses are the likely cause of long Covid.

30 Jan 2024

New scientific statement outlines recommendations for diagnosing, managing cerebral venous thrombosis

A new scientific statement from the American Heart Association emphasizes the need to increase patients' and physicians' awareness of cerebral venous thrombosis (CVT) to improve the recognition of this condition and initiate prompt medical treatment.

29 Jan 2024

Study finds patients with long COVID exhibit complement dysregulation with signs of thromboinflammation

Researchers explore inflammatory signatures restricted to patients with active post-acute COVID-19 sequelae.

23 Jan 2024

Revolutionary bio-sponge halts bleeding instantly

More than 11 million people in the United States take anticoagulation or antiplatelet medications, such as heparin or aspirin, to treat serious conditions like heart attack and stroke.

22 Jan 2024

New study reveals key blood markers for sepsis diagnosis in burn patients

The efficacy of Complete Blood Count (CBC) parameters in diagnosing sepsis.

10 Jan 2024

Blood tests can detect inflammatory bowel disease years before symptoms appear

Researchers at the Francis Crick Institute and Aalborg University in Copenhagen have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis.

7 Nov 2023

New score predicts risk of postoperative liver failure with high accuracy

Surgical removal of parts of the liver remains the only curative approach for patients with liver-specific cancer.

2 Nov 2023

Scientists identify mechanism causing deadly blood clots after some COVID-19 vaccines

A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.

30 Oct 2023

Could young blood be the key to reversing age-related cognitive decline?

Researchers at the University of Auckland identify platelet factor 4 (PF4) in young blood as a key player in reversing age-related cognitive decline in mice. The study offers a promising avenue for treating dementia-related conditions and enhancing brain function in aging populations.

11 Oct 2023

Parasites that cause visceral leishmaniasis can infect non-immune cells, study finds

The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.

29 Sep 2023

Pitt launches trial to test interventions for life-threatening bleeding in injured children

The No. 1 cause of death in children is trauma. There are an estimated 2,000 pediatric deaths from traumatic bleeding in the U.S. each year that are preventable with optimal care, yet there have been no large-scale clinical trials to guide the best way to resuscitate children with life-threatening bleeding from traumatic injury.

21 Sep 2023

Mapping the human body one cell at a time: New study reveals the intricate relationship between cell size and count

A study published in PNAS provides a comprehensive look at the relationship between cell size and count across the human body, drawing from over 1,500 sources and identifying around 400 unique cell types. The research reveals an almost inverse relationship between cell size and count, offering a quantitative framework that could serve as a baseline for understanding cellular composition and function in various applications.

19 Sep 2023