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Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

The authors of a new study under review at the journal Scientific Reports and currently posted to the Research Square preprint* server proposed a novel analysis pipeline to help identify mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription-polymerase chain reaction (RT-PCR) primer regions.

29 Mar 2023

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Researchers assessed the efficiency of a genetic decoding system for diagnosing non-small cell lung cancer (NSCLC).

16 Mar 2023

Important backup mechanism of human immune cells elucidated

The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses.

10 Mar 2023

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers highlight recent research investigating whether gut microbiota regulates tau pathology and tau-mediated neurodegeneration in an ApoE isoform–dependent manner.

21 Feb 2023

Cryo-electron microscopy captures the first 3D structure of SPOP protein that drives cancer

SPOP is the most mutated protein in prostate cancer and plays a role in endometrial, uterine and other cancers. Despite this importance, how SPOP mutations drive cancer has been incompletely understood.

23 Jan 2023

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

Researchers evaluated the use of receptor decoys for SARS-CoV-2 based on soluble forms of ACE2 for immunological prophylaxis and management of COVID-19 through the use of AAV vectors.

16 Jan 2023

Point mutation News and Research

Study finds minimal impact of SARS-CoV-2 genome variability on current diagnostic molecular systems

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Important backup mechanism of human immune cells elucidated

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Cryo-electron microscopy captures the first 3D structure of SPOP protein that drives cancer

Researchers report that vectored expression of a high-affinity ACE2 microbody protein establishes a high degree of protection from SARS-CoV-2

New insights on the circadian clock of Drosophila melanogaster

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Bivalent recombinant vaccine protects against SARS-CoV-2 and influenza in animal models

Fast and sensitive paper-based nucleic acid assay for SARS-CoV-2

UCI researchers develop novel test that detects specific SARS-CoV-2 variants with 100% accuracy

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

The impact of the SARS-CoV-2 spike A222V mutation on viral infection

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

SARS-CoV-2-specific T cells are broader after vaccination than after infection

Genetic cause of lupus identified

Researchers develop new platform capable of mitochondrial DNA editing

New, longest documented case of persistent acute SARS-CoV-2 infection

SARS-CoV-2 Delta-Omicron recombinant identified in a transplant patient treated with Sotrovimab

Researchers show how an important inhibitor binds to the A2A receptor

Hasret Altan-Martin

Speeding Up Sample Preparation to Accelerate Analytical Chemistry

Ask the Expert: 7 Questions about Colorectal Cancer & Non-invasive Fecal DNA Testing

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