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Eating for health: how dietary interventions impact pre-diabetic oral and gut microbiome, metabolites and cytokines

Researchers evaluated the impact of two diets on the intestinal and oral microbiota, cytokines, and metabolites of 200 pre-diabetic individuals.

7 Sep 2023

One in three men carry HPV: The ignored reservoir in the fight against cancer

One in three men over 15 globally have at least one incidence of genital HPV, underscoring the need to include males in HPV prevention strategies. The prevalence remains high from young adulthood through later life, particularly for high-risk HPV types linked to cancers.

6 Sep 2023

COVID-19 hits American Indian and Alaska Native populations hardest, new study reveals

A recent study at the University of New Mexico Hospital highlights that American Indian and Alaska Native populations face disproportionate severity and mortality rates from COVID-19. The research points to the urgent need for targeted interventions and resources to address these health disparities.

5 Sep 2023

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

Around 5.2% of the global population carries abnormal hemoglobin genes. Each year, 300,000 to 500,000 children are born with severe hemoglobinopathies worldwide, with approximately 80% of these cases occurring in developing countries.

5 Sep 2023

SARS-CoV-2 Eris variant spreads faster and dodges immunity

Study investigates the characteristics of the EG.5.1 "Eris" variant of SARS-CoV-2, finding it more transmissible among hamsters and slightly better at evading immunity compared to the XBB.1.5 variant. The results suggest that these properties could be driving the variant's increasing prevalence in human populations.

5 Sep 2023

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Researchers have developed a new blood test that measures mitochondrial DNA damage as a potential marker for Parkinson's disease (PD). The study shows the test could aid in diagnosing PD and assessing responses to LRRK2 kinase inhibitors, which may help in reducing mitochondrial damage in PD patients.

4 Sep 2023

Study reports highly pathogenic avian influenza A infection in pet dogs and cat on a rural poultry farm in Italy

Researchers presented serological evidence of highly pathogenic avian influenza (HPAI) H5N1 virus infection in a pet cat and five dogs on a rural poultry farm in Italy.

4 Sep 2023

Wild boars and Hepatitis E: Whats the zoonotic risk?

The prevalence of the Hepatitis E virus (HEV) in the Portuguese wild boar population.

4 Sep 2023

The first point-of-care genetic test for lactose intolerance: A compact, lab-on-phone diagnostic assay

The performance of a compact diagnostic assay that can accurately and rapidly diagnose lactose intolerance.

4 Sep 2023

Is the rapid evolution of SARS-CoV-2 in white-tailed deer complicating our fight against the pandemic?

New study reveals rapid evolution of SARS-CoV-2 in Ohio's white-tailed deer population, with a 25% seroprevalence rate. The findings suggest a significant risk of animal-to-human transmission and indicate the virus evolves faster in deer than in humans.

31 Aug 2023

Fourth COVID-19 booster supercharges antibody defense in older adults, study says

The study finds that the fourth dose of the COVID-19 mRNA vaccine significantly boosts neutralizing antibody levels in the elderly, providing enhanced protection against new SARS-CoV-2 variants like Omicron. This supports the efficacy of booster shots for older populations in combating COVID-19.

31 Aug 2023

Parkinson's disease diagnosis could be made earlier with new blood test

Researchers have developed a blood test that detects Parkinson's disease, potentially establishing a way to help diagnose the condition before nervous system damage worsens.

30 Aug 2023

Scientists create library of mutant bacteria to study antibiotic resistance

Modern medicine depends on antibiotics to treat infections by disabling targets inside bacterial cells. Once inside these cells, antibiotics bind to certain sites on specific enzyme targets to stop bacterial growth.

30 Aug 2023

How frequent are hospital-onset SARS-CoV-2 infections and what hospital characteristics are associated with rates of hospital-onset SARS-CoV-2 infections?

Researchers investigated the frequency of hospital-onset COVID-19 cases and the hospital characteristics related to hospital-onset infections by SARS-CoV-2 in US.

30 Aug 2023

Study examines health impacts of second-hand cigarette smoke exposure

In a recent study, researchers evaluated the effects of chronic second-hand smoke exposure on cognition, behavior, neuropathology, and metabolism.

29 Aug 2023

Study finds evidence of SARS-CoV-2 exposure in many patients with postviral syndrome

Researchers investigated immunologic and clinical findings indicative of SARS-CoV-2 exposure among individuals with postviral syndrome.

29 Aug 2023

Dual CRISPR-Cas3 is a promising tool to induce a gigantic genomic deletion and restore dystrophin protein

Researchers evaluated the use of a dual clustered regularly interspaced short palindromic repeats (CRISPR)-Cas3 system.

29 Aug 2023

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

This recent study identifies new urinary biomarkers for detecting acute COVID-19 using spectroscopic analysis. The findings reveal that these biomarkers could offer valuable tools for early diagnosis, understanding the severity of the disease, and possibly contribute to endogenous immunological defense mechanisms against SARS-CoV-2.

29 Aug 2023

Could automated, saliva-based PCR testing be the future of COVID-19 surveillance?

In a large-scale study funded by Kings College London, researchers successfully implemented an automated PCR-based testing program for SARS-CoV-2 using saliva samples from asymptomatic students and staff. The system achieved 85% sensitivity and 100% specificity, provided rapid results within eight hours, and offered a cost-effective and scalable approach to community surveillance of COVID-19.

28 Aug 2023

A comprehensive online resource allows for the exploration of interactions between mutational signatures and topographical features across human cancer

An online resource for studying the relationship between mutational signatures and topographical characteristics across human cancer.

28 Aug 2023

Polymerase News and Research

Eating for health: how dietary interventions impact pre-diabetic oral and gut microbiome, metabolites and cytokines

One in three men carry HPV: The ignored reservoir in the fight against cancer

COVID-19 hits American Indian and Alaska Native populations hardest, new study reveals

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

SARS-CoV-2 Eris variant spreads faster and dodges immunity

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Study reports highly pathogenic avian influenza A infection in pet dogs and cat on a rural poultry farm in Italy

Wild boars and Hepatitis E: Whats the zoonotic risk?

The first point-of-care genetic test for lactose intolerance: A compact, lab-on-phone diagnostic assay

Is the rapid evolution of SARS-CoV-2 in white-tailed deer complicating our fight against the pandemic?

Fourth COVID-19 booster supercharges antibody defense in older adults, study says

Parkinson's disease diagnosis could be made earlier with new blood test

Scientists create library of mutant bacteria to study antibiotic resistance

How frequent are hospital-onset SARS-CoV-2 infections and what hospital characteristics are associated with rates of hospital-onset SARS-CoV-2 infections?

Study examines health impacts of second-hand cigarette smoke exposure

Study finds evidence of SARS-CoV-2 exposure in many patients with postviral syndrome

Dual CRISPR-Cas3 is a promising tool to induce a gigantic genomic deletion and restore dystrophin protein

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

Could automated, saliva-based PCR testing be the future of COVID-19 surveillance?

A comprehensive online resource allows for the exploration of interactions between mutational signatures and topographical features across human cancer

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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