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Alarming spread of H5N1 bird flu in US dairy cattle reveals cross-species transmission dangers

Researchers discovered that the H5N1 avian influenza virus has spilled over into dairy cattle in the US, posing significant cross-species transmission risks. Their multidisciplinary study reveals the virus's evolution and its zoonotic potential, emphasizing the need for heightened biosecurity measures.

25 Jul 2024

Long-term immune changes persist in unvaccinated COVID-19 patients

Study reveals that unvaccinated individuals experience significant long-term changes in immune parameters up to ten months post-COVID-19 infection, with a shift towards a Th2 cytokine profile.

21 Jul 2024

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Xueqing Hu , Ujjwol Khatri , Tao Shen , and Jie Wu, at University of Oklahoma Health Sciences Center, USA, provides a comprehensive review of the role of the RET (REarranged during Transfection) receptor tyrosine kinase in cancer development and the advancements in RET-targeted cancer therapies.

19 Jul 2024

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Blocking IL-11 signaling extends lifespan and healthspan in mice, reducing age-related metabolic decline, frailty, and cancer incidence.

18 Jul 2024

Harnessing ctDNA measurements for response assessment in metastatic castration resistant prostate cancer

A new editorial paper was published in Oncotarget's Volume 15 on July 2, 2024, entitled, "Using early on-treatment circulating tumor DNA measurements as response assessment in metastatic castration resistant prostate cancer."

18 Jul 2024

Study finds dairy cows vulnerable to flu strains from birds, humans, and pigs

Researchers compared the distribution of sialic acid receptors in the respiratory tract and mammary glands of dairy cattle naturally infected with the highly pathogenic avian influenza A(H5N1) virus.

18 Jul 2024

First trimester COVID-19 exposure and vaccination not tied to major birth defects

Neither covid-19 infection nor vaccination during the first trimester of pregnancy is associated with increased risk of major birth defects, finds a study from Scandinavia published by The BMJ today.

18 Jul 2024

One-time prime editing targets common genetic cause of cystic fibrosis

Researchers optimized prime editing for the efficient correction of the cystic fibrosis transmembrane conductance regulator F508del mutation in human airway epithelial cells, achieving high correction efficiencies and functional restoration with minimal off-target effects.

15 Jul 2024

Salads under scrutiny: Study reveals contamination risks and solutions in ready-to-eat salads

The research paper highlights critical contamination points in the production of ready-to-eat salads and discusses solutions to ensure microbiological safety and health.

10 Jul 2024

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.

10 Jul 2024

INTEGRA Biosciences’ pipettes help to cultivate success in agriculture

The National Agricultural Research and Development Institute (NARDI) in Fundulea, Romania, relies on electronic multichannel pipettes from INTEGRA Biosciences to streamline its liquid handling workflows.

From INTEGRA Biosciences 9 Jul 2024

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.

7 Jul 2024

Scientists unveil KLF15 transcription factor's role in white fat cells, opening new paths for obesity therapy

Researchers found that KLF15 is crucial for maintaining white adipocyte properties in subcutaneous fat, and its deletion induces beige adipocyte characteristics, suggesting new obesity treatment pathways.

4 Jul 2024

New study reveals how RNA polymerase opens the transcription bubble in real time

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA.

3 Jul 2024

Frequent infections and pathobionts boost children's nasal immunity, study reveals

Dynamic interactions with viruses and bacterial pathobionts significantly enhance nasal innate immunity in children, revealing distinct immunophenotypes driven by microbial load and type.

2 Jul 2024

FDA commercial pasteurization process kills H5N1 bird flu virus in milk

A study by FDA and USDA confirms that commercial milk pasteurization effectively inactivates the Highly Pathogenic H5N1 Avian Influenza virus in cattle milk. This ensures the safety of the U.S. milk supply against this virus.

2 Jul 2024

Bird flu virus detected in Alaskan polar bear

Researchers reported a natural infection of a highly pathogenic avian influenza A(H5N1) virus in a free-ranging juvenile polar bear in Alaska, highlighting the importance of wildlife health surveillance in detecting emerging pathogens.

2 Jul 2024

Study finds specific gut microbiota signature is associated with vulnerability to food addiction

Researchers of a recent study published in Gut explored gut microbial involvement in food addiction-related processes.

1 Jul 2024

AI identifies new high-risk subtype in endometrial cancer

An AI tool to classify histopathological images and differentiate between endometrial cancer subtypes.

28 Jun 2024

Adaptive therapy approach can reduce toxicity and drug resistance in ovarian cancer

Ovarian cancer, often diagnosed at an advanced stage, presents significant treatment challenges because patients tend to develop resistance to conventional therapies quickly.

26 Jun 2024

Polymerase News and Research

Alarming spread of H5N1 bird flu in US dairy cattle reveals cross-species transmission dangers

Long-term immune changes persist in unvaccinated COVID-19 patients

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Harnessing ctDNA measurements for response assessment in metastatic castration resistant prostate cancer

Study finds dairy cows vulnerable to flu strains from birds, humans, and pigs

First trimester COVID-19 exposure and vaccination not tied to major birth defects

One-time prime editing targets common genetic cause of cystic fibrosis

Salads under scrutiny: Study reveals contamination risks and solutions in ready-to-eat salads

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

INTEGRA Biosciences’ pipettes help to cultivate success in agriculture

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Scientists unveil KLF15 transcription factor's role in white fat cells, opening new paths for obesity therapy

New study reveals how RNA polymerase opens the transcription bubble in real time

Frequent infections and pathobionts boost children's nasal immunity, study reveals

FDA commercial pasteurization process kills H5N1 bird flu virus in milk

Bird flu virus detected in Alaskan polar bear

Study finds specific gut microbiota signature is associated with vulnerability to food addiction

AI identifies new high-risk subtype in endometrial cancer

Adaptive therapy approach can reduce toxicity and drug resistance in ovarian cancer

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

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