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Emerging tick-borne viral threats in eastern europe and the black sea basin

Tick samples from countries in Eastern Europe and the Black Sea region.

16 Nov 2023

One in five patients on Nirmatrelvir–Ritonavir experience virologic rebound, new observational study reveals

The frequency of viral rebound (VR) among acute coronavirus disease 2019 patients.

16 Nov 2023

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival.

15 Nov 2023

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

Study demonstrates the use of cellulose nanofiber sheets for spatial analysis of extracellular vesicles, revealing their geographical heterogeneity in the human body, which could advance the understanding and treatment of diseases.

14 Nov 2023

Hospital-acquired COVID-19 mortality drops in Omicron era post-vaccination, reveals Swedish study

In a study published in JAMA Network Open, researchers found that hospital-acquired SARS-CoV-2 infections in Stockholm led to increased 30-day mortality in the pre-vaccination period but showed significantly lower mortality during the Omicron wave post-vaccination. The study underscores the importance of vaccination in reducing mortality risks from nosocomial SARS-CoV-2 infections.

13 Nov 2023

Researchers identify key factors involved in DNA repair mechanism

Researchers from Tokyo Metropolitan University have identified key factors in the mechanism behind DNA repair in our bodies.

12 Nov 2023

Allergies linked to heightened risk of long COVID, new review suggests

Systematic review indicates that pre-existing allergic conditions like asthma and allergic rhinitis may be linked to an increased risk of developing long COVID. Despite some evidence, the certainty remains low due to potential biases and confounding factors, highlighting the need for more rigorous research to determine the impact of these allergies on prolonged COVID-19 symptoms.

9 Nov 2023

New research aims to decipher how animals discard half their genes

New research is underway to decipher a fascinating biological puzzle-;how some animals can naturally discard more than half of their genetic information during embryonic development.

9 Nov 2023

SSRIs show promise in easing post-COVID struggles, Dutch study reveals

Dutch study finds SSRIs significantly alleviate post-COVID syndrome symptoms, offering promising treatment avenues and shedding light on neurobiological mechanisms at play.

5 Nov 2023

Decoding long COVID, pathophysiology, epidemiology, diagnosis, and management

Comprehensive review unravels the complexities of long COVID, spanning pathophysiology to management strategies, and underscores the need for targeted therapies and early diagnosis.

5 Nov 2023

New virus diagnosis device gives lab-quality results within just three minutes

A virus diagnosis device that gives lab-quality results within just three minutes has been invented by engineers at the University of Bath, who describe it as the 'world's fastest Covid test'.

2 Nov 2023

Added calcium and phosphate in fluoride varnishes no silver bullet for fighting kids' tooth decay, study finds

The study explores the effectiveness of sodium fluoride varnishes with added calcium and phosphate versus conventional varnishes in reducing harmful bacteria in preschool children's mouths. Results indicate no significant difference between the two types of varnishes in controlling bacterial growth, calling for more research on effective ways to combat early childhood caries.

1 Nov 2023

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

Researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications.

1 Nov 2023

How one gene shakes up our understanding of male infertility

The study investigates the role of the ACTL7B gene in sperm formation using genetically modified mice and finds that deficiencies in this gene lead to failed spermatogenesis and structural sperm abnormalities. Given the gene's similarity in humans, the findings suggest ACTL7B could serve as a potential biomarker for male infertility.

31 Oct 2023

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

The study reveals that introducing progerin, a protein associated with accelerated aging, into cellular models of Alzheimer's Disease (AD) can hasten the development of AD-related traits. This innovative approach offers a more efficient method for studying AD mechanisms, potentially accelerating the discovery of new treatments.

31 Oct 2023

COVID-19’s long reach: Some physical symptoms can persist up to two years post-diagnosis

Researchers investigated the prevalence rate of physical-type symptoms by the severity of acute COVID-19 beyond two years of diagnosis.

31 Oct 2023

Human-to-lion COVID transmission confirmed: Singapore study rings alarm bells for endangered species

The study reveals that the SARS-CoV-2 delta variant was transmitted from humans to lions at a Singapore zoo, emphasizing the risk to captive and endangered animals. The researchers call for strict infection control measures and suggest vaccinations for susceptible animals to protect them from anthropogenic viral transmissions.

30 Oct 2023

Polymerase News and Research

Emerging tick-borne viral threats in eastern europe and the black sea basin

One in five patients on Nirmatrelvir–Ritonavir experience virologic rebound, new observational study reveals

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

Hospital-acquired COVID-19 mortality drops in Omicron era post-vaccination, reveals Swedish study

Researchers identify key factors involved in DNA repair mechanism

Allergies linked to heightened risk of long COVID, new review suggests

New research aims to decipher how animals discard half their genes

SSRIs show promise in easing post-COVID struggles, Dutch study reveals

Decoding long COVID, pathophysiology, epidemiology, diagnosis, and management

New virus diagnosis device gives lab-quality results within just three minutes

Added calcium and phosphate in fluoride varnishes no silver bullet for fighting kids' tooth decay, study finds

Proof-of-concept study holds promise for safer gene therapy techniques for treating immunodeficiencies

How one gene shakes up our understanding of male infertility

Speeding up Alzheimer's research: Progerin turbocharges cellular models for quicker drug screening

COVID-19’s long reach: Some physical symptoms can persist up to two years post-diagnosis

Human-to-lion COVID transmission confirmed: Singapore study rings alarm bells for endangered species

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

AI-nanopore platform can detect SARS-CoV-2 variants with high accuracy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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