Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Long-COVID recovery insight: Fatigue and cognitive deficits improve over two years

Study reveals improvements in cognitive deficits and fatigue among long-COVID patients over two years, with specific risk factors like depressive symptoms and old age predicting non-recovery.

5 Feb 2024

XBB.1.5 updated COVID vaccine booster offers 54% increased protection against symptomatic infection

Early estimates show the 2023-24 updated monovalent XBB.1.5 COVID-19 vaccine offers significant protection against symptomatic infection, with effectiveness varying by age and time since vaccination.

4 Feb 2024

New sequencing tool speeds up SARS-CoV-2 outbreak response and informs treatment

Announcing a new article publication for Zoonoses journal. In the context of two Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outbreaks involving local transmission and an international flight, the authors of this article used meta-transcriptome and multi-amplicon sequencing to successfully acquire the complete viral genome sequences from clinical samples with varying viral loads.

1 Feb 2024

Immunocompromised patients show prolonged SARS-CoV-2 infection and unique mutations

study identifies risk factors for prolonged SARS-CoV-2 infection in immunocompromised patients, revealing that B-cell dysfunction, solid organ transplantation, and AIDS lead to longer infections and unique spike mutations.

31 Jan 2024

Immune protein Ku70 key in fighting bowel cancer

Study establishes Ku70's role in tumor suppression, showing that reduced expression or mutations in this DNA repair protein significantly increase intestinal cancer risk.

30 Jan 2024

Study reveals significant health benefits of golden berries in diabetic and obese rats

The effects of a Golden Berry (Physalis peruviana)-enriched diet on insulin resistance and obesity.

30 Jan 2024

Netherlands sees unexpected surge in Mycoplasma pneumoniae cases, younger population more affected

A study in the Netherlands reports a significant rise in Mycoplasma pneumoniae infections since October 2023, with a notable decrease in the median age of patients compared to the last epidemic.

28 Jan 2024

The association between handgrip strength and functional outcomes in long COVID-19

The association between dynapenia with long coronavirus disease 2019 (COVID-19).

26 Jan 2024

RT-PCR genotyping outperforms whole-genome sequencing in speedy and accurate COVID-19 variant tracking

A study in JAMA Network Open shows RT-PCR genotyping assays as a faster, cost-effective alternative to WGS for SARS-CoV-2 variant surveillance, offering high accuracy and scalability.

24 Jan 2024

Lung cancer prediction using biomarkers based on bronchoalveolar fluid microbiomes

The lung microbiomes of patients with benign and malignant pulmonary diseases.

23 Jan 2024

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Researchers explored how Death Induced by Survival gene Elimination through the analysis of RNA-induced silencing complex-bound short RNAs in Alzheimer's disease models influences neuronal survival and correlates with neurotoxicity in AD.

22 Jan 2024

Innovative COVID-19 test prototype uses bioluminescence for speedier results

Researchers used a luciferase-independent luminescence test to investigate whether the wild-type SARS-CoV-2 spike protein possesses pseudo-luciferase activity for Cypridina luciferin.

22 Jan 2024

Study assesses effectiveness of strategies to prevent SARS-CoV-2 transmission in healthcare settings

Researchers analyzed whether infection prevention measures during the COVID-19 pandemic were adequate in protecting healthcare workers.

22 Jan 2024

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers compared SARS-CoV-2 Omicron variant of concern replication in human cell lines and primary airway cultures and measured host responses to infection.

19 Jan 2024

Comprehensive analysis of more than 2 million SARS-CoV-2 samples detects co-infections and intra-host recombination

Researchers evaluated the prevalence of co-infection and intra-host recombination in over 2 million global SARS-CoV-2 cases and developed strategies for accurate identification and analysis of recombinant strains.

17 Jan 2024

Combining health data with whole genome sequence data in cancer patients can help doctors provide more tailored care

Researchers evaluated the impact of integrating whole-genome sequencing data with clinical outcomes across 13,880 tumors from 33 cancer types, assessing precision care potentials within the UK NHS through the 100,000 Genomes Cancer Programme.

16 Jan 2024

New study shows how brain glucose affects fungal disease treatment

Metabolite-drug-fungal interactions in the fungal meningitis pathogen Cryptococcus neoformans.

16 Jan 2024

Study reveals key role of skin microbiome in aging and skin health

Microbial taxa related to skin aging.

16 Jan 2024

Study finds that HIV populations in people with higher viral loads also have higher rates of viral recombination

Researchers investigated whether denser intrahost HIV populations had a higher incidence of coinfection and recombination.

15 Jan 2024

mRNA COVID-19 vaccines highly effective in preventing hospitalizations among adolescents in Nordic study

Study evaluated the effectiveness of mRNA COVID-19 vaccines (BNT162b2, mRNA-1273, and heterologous schedules) in preventing hospitalization among adolescents in Nordic countries, finding high protection rates of 73% to 86% at six months.

14 Jan 2024

Polymerase Chain Reaction News and Research

Further Reading

Long-COVID recovery insight: Fatigue and cognitive deficits improve over two years

XBB.1.5 updated COVID vaccine booster offers 54% increased protection against symptomatic infection

New sequencing tool speeds up SARS-CoV-2 outbreak response and informs treatment

Immunocompromised patients show prolonged SARS-CoV-2 infection and unique mutations

Immune protein Ku70 key in fighting bowel cancer

Study reveals significant health benefits of golden berries in diabetic and obese rats

Netherlands sees unexpected surge in Mycoplasma pneumoniae cases, younger population more affected

The association between handgrip strength and functional outcomes in long COVID-19

RT-PCR genotyping outperforms whole-genome sequencing in speedy and accurate COVID-19 variant tracking

Lung cancer prediction using biomarkers based on bronchoalveolar fluid microbiomes

Discovery of toxic and protective short RNAs associated with Alzheimer's disease and superior memory capacity

Innovative COVID-19 test prototype uses bioluminescence for speedier results

Study assesses effectiveness of strategies to prevent SARS-CoV-2 transmission in healthcare settings

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Comprehensive analysis of more than 2 million SARS-CoV-2 samples detects co-infections and intra-host recombination

Combining health data with whole genome sequence data in cancer patients can help doctors provide more tailored care

New study shows how brain glucose affects fungal disease treatment

Study reveals key role of skin microbiome in aging and skin health

Study finds that HIV populations in people with higher viral loads also have higher rates of viral recombination

mRNA COVID-19 vaccines highly effective in preventing hospitalizations among adolescents in Nordic study

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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