Positron Emission Tomography News and Research

RSS

Scientists generate 3D ultra-resolution maps of mitochondrial networks in lung tumors

Scientists have long known that mitochondria, the "powerhouses" of cells, play a crucial role in the metabolism and energy production of cancer cells.

15 Mar 2023

An overview of COVID-19-associated neurological complications in children

Researchers review current literature to understand the association between COVID-19, neuroimaging, and neurological symptoms in children.

14 Mar 2023

Research helps explain the metabolic differences of people living at high altitudes

Compared to those of us who live at sea level, the 2 million people worldwide who live above 4,500 meters (or 14,764 feet) of elevation-;about the height of Mount Rainier, Mount Whitney, and many Colorado and Alaska peaks-;have lower rates of metabolic diseases such as diabetes, coronary artery disease, hypercholesterolemia, and obesity.

7 Mar 2023

What are the clinical considerations of proton radiotherapy for individuals with locally advancing breast cancer?

In a recent review published in Current Oncology, researchers highlighted the technical and clinical considerations for proton radiotherapy delivery for individuals with locally advancing breast malignancies.

1 Mar 2023

The natural history of tau accumulation and the impact of disease stage and reference region on the magnitude and effect size of regional change

Researchers performed serial tau imaging with 18F-MK6240 to detect tau accumulation in cognitively unimpaired beta-amyloid negative Alzheimer’s disease patients as well as those with mild cognitive impairment who were Aβ+ at baseline.

27 Feb 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers presented eight hallmarks of neurodegenerative diseases (NDDs), their in vivo biomarkers, and interactions to help categorize NDDs and specify patients within a specific NDD.

21 Feb 2023

Changes in brain aerobic glycolysis reflect aging-related pathologies in Alzheimer’s

Researchers explore aerobic glycolysis in the brain and its resilience during Alzheimer's disease.

8 Feb 2023

New scan reliably detects primary aldosteronism, a common cause of hypertension

In a recent article, researchers performed a prospective within-patient clinical trial, Is Metomidate superior to AVS in predicting ouTComes from adrenalectomy in primary Hyperaldosteronism (MATCH) in the United Kingdom (UK) in primary aldosteronism (PA) patients. These patients suffered from high blood pressure caused by a steroid hormone, aldosterone.

19 Jan 2023

Study explores the role of endocannabinoids in hazardous drinking among young adults

Although heavy drinking in young adulthood increases the risk for alcohol use disorder (AUD), not all young heavy drinkers go on to develop AUD, globally the most common substance use disorder.

18 Jan 2023

Caterpillars could be used as an alternative to mammalian models to study gut inflammation

Rats and mice have been the backbone of biomedical research for decades -; including research to understand cancer and pioneer new treatments.

12 Jan 2023

Wearable skin patch could help clinicians diagnose tumors, organ malfunction and more

Novel skin patch capable of deep detection of hemoglobin and core temperature.

22 Dec 2022

New support for a serotonin deficit in depression

Since the 1960s, researchers have postulated that major depression stems from disruptions in the serotonin neurotransmitter system, but the evidence for that idea, though plentiful, was indirect.

16 Dec 2022

People with Alzheimer’s and Down syndrome may benefit from participating in Alzheimer’s clinical trials

Amyloid plaques — protein clumps that are one of the hallmarks of Alzheimer's disease—occur at roughly the same level in the brains of people with Down syndrome who have Alzheimer's as they do in people with forms of hereditary, early-onset Alzheimer's, according to research funded by the National Institutes of Health.

12 Dec 2022

New method for determining the need for coronary stents, bypass surgery more effective than angiogram

A new method for determining whether patients with heart disease need coronary stents or bypass surgery is more effective than the angiogram, which is currently used, according to research from UTHealth Houston Heart & Vascular.

30 Nov 2022

Study identifies a urinary biomarker to reveal early-stage Alzheimer’s disease

Could a simple urine test reveal if someone has early-stage Alzheimer’s disease and could this pave the way for large-scale screening programs? A new study in Frontiers in Aging Neuroscience certainly suggests so. The researchers tested a large group of patients with Alzheimer’s disease of different levels of severity and healthy controls with normal cognition to identify differences in urinary biomarkers.

30 Nov 2022

Machine learning pinpoints the most accurate timelines for predicting Alzheimer's progression

A Cornell-led collaboration used machine learning to pinpoint the most accurate means, and timelines, for anticipating the advancement of Alzheimer's disease in people who are either cognitively normal or experiencing mild cognitive impairment.

28 Nov 2022

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

Addressing this gap in research, a recent Nature Medicine study hypothesized that 4R isoform-specific MTBR-tau species accumulate in the patient’s brain of specific subtypes of 4R tauopathies.

28 Nov 2022

Researchers to develop brain imaging radiotracers for better understanding of Alzheimer's, autism

Emory researchers are on the cusp of seeing in real time how brain diseases like Alzheimer's and autism spectrum disorder affect a patient's brain function.

21 Nov 2022

Inhibitory neuron dysfunction emerges as a modulable mechanism of hyperexcitability

A small group of brain cells linked in a circuit is responsible for setting off whole-brain seizures in a rare form of epilepsy affected by blood sugar levels, a study led by UT Southwestern researchers suggests. The finding, published in Science Translational Medicine, could lead to new treatments for other metabolic disorders in the brain, the authors said.

17 Nov 2022

AI tool uses CT scans to identify patients at risk of reduced blood flow to the heart

Cedars-Sinai investigators and colleagues have developed an artificial intelligence (AI) tool that uses computed tomography (CT) scans to identify patients at risk of reduced blood flow to the heart.

14 Nov 2022