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Comprehensive dataset from A4 study yields key insights about Alzheimer's disease

Data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) study, the first and largest clinical trial of pre-symptomatic Alzheimer's disease, is now widely available to researchers studying the condition.

24 Jul 2024

A reliable artificial intelligence-guided marker for early dementia prediction

Researchers use machine learning techniques to develop and test a predictive prognostic model to predict dementia early using real-world patient data.

18 Jul 2024

Predicting Alzheimer's decline: New model offers personalized insights for patients

Researchers developed a model to predict cognitive decline in Alzheimer's patients using clinical and biomarker data, improving personalized treatment plans.

16 Jul 2024

Immunotherapy response assessment in malignant pleural mesothelioma: FDG-PET/CT vs. CT

A new research paper was published in Oncotarget's Volume 15 on June 20, 2024, entitled, "Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma."

15 Jul 2024

Revolutionary AI model improves early dementia diagnosis

Cambridge scientists have developed an artificially-intelligent tool capable of predicting in four cases out of five whether people with early signs of dementia will remain stable or develop Alzheimer’s disease.

13 Jul 2024

Researchers develop a more accurate way to scan for tuberculosis using PET

A more accurate way to scan for tuberculosis (TB) has been developed by UK and US researchers, using positron emission tomography (PET).

27 Jun 2024

Blood-based biomarkers could revolutionize Alzheimer's diagnosis and treatment

A recent review outlines the necessary factors for widespread implementation and interpretation of Alzheimer's disease blood-based biomarkers (BBMs) at the population level, emphasizing the potential for early detection and improved diagnosis.

14 Jun 2024

UC Davis pioneers advanced PET imaging to monitor lung cancer treatment

Lung cancer can advance quickly. Once a person starts treatment, it is vital to know if that treatment is working or if the patient should be switched to a different treatment.

10 Jun 2024

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation.

28 May 2024

$Osaka University to pioneer world-first clinical trial for refractory prostate cancer with alpha-ray therapy$

Osaka University to pioneer world-first clinical trial for refractory prostate cancer with alpha-ray therapy

A research team at Osaka University will start an investigator-initiated clinical trial for refractory prostate cancer patients after the successful development of a new alpha-ray therapeutic agent ([At-211] PSMA-5) and confirmation of its efficacy in animal models.

27 May 2024

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

A study published in Nature Medicine delineates how APOE4 homozygosity distinctly accelerates Alzheimer's disease pathology and biomarkers from the age of 55, suggesting a unique form of the disease and a potential focus for targeted therapies.

8 May 2024

New discovery offers dietary solution for pulmonary hypertension

Blood vessels in the lungs aren't like the others in the body. This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death.

2 May 2024

PET brain scans could reveal hidden inflammation in patients with multiple sclerosis

A Brigham and Women’s Hospital study of 30 people found that, in patients with MS, advanced brain imaging could identify hidden inflammation not picked up on traditional MRIs

27 Apr 2024

UC San Diego researchers secure NIH grants to develop noninvasive immune cell imaging technology

Researchers at University of California San Diego School of Medicine have been awarded two new grants by the National Institutes of Health (NIH), totaling $6.7 million, to develop and clinically test technologies that can noninvasively examine and quantify immune cells found in tumors.

1 Apr 2024

Study demonstrates safe reduction of lymph node removal in breast cancer patients

Patients with breast cancer that has started to spread to the lymph nodes in the armpit can safely avoid extensive removal of the lymph nodes if their treatment is tailored to their response to cancer-killing therapies such as chemotherapy before surgery.

22 Mar 2024

Combined scanning technique could refine treatment for early-stage breast cancer patients

Using a combined scanning technique on patients with early-stage breast cancer improved treatment in almost three out of ten cases in a trial presented at the 14th European Breast Cancer Conference today.

21 Mar 2024

Computer model can find signs of lymph node cancer in 90% of cases

Medical image analysis using AI has developed rapidly in recent years. Now, one of the largest studies to date has been carried out using AI-assisted image analysis of lymphoma, cancer of the lymphatic system.

14 Mar 2024

Study highlights potential of p-tau217 assays in Alzheimer's clinical trials and diagnosis

The performance of two commercial phospho-tau217 (p-tau217) assays.

14 Mar 2024

Study reveals link between blood amyloid levels and brain microstructure changes in Alzheimer's

New research published today suggests there is a link between abnormal blood levels of amyloid -; a protein associated with Alzheimer's disease -; and subtle changes in brain microstructures on a type of MRI, findings that could lead to a new way to detect Alzheimer's earlier in people with no clinical signs.

6 Mar 2024

How does cancer impact cognitive decay?

The risk of mild cognitive impairment (MCI) and Alzheimer's disease (AD) among cancer patients.

26 Feb 2024