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Innovative molecular biology technique used to identify targets for Schistosoma mansoni vaccine candidates

Researchers in Brazil have used an innovative technique in molecular biology to identify targets for candidate vaccines against Schistosoma mansoni, the parasite that causes schistosomiasis.

2 Apr 2024

New compound shows promise as a more effective treatment for schistosomiasis

A newly developed compound is showing promise in animal studies as a more effective treatment for human schistosomiasis, an understudied tropical disease caused by parasitic worms.

25 Mar 2024

Researchers uncover novel targets for treatment of schistosomiasis

The worms that cause schistosomiasis (Schistosoma mansoni) are unusual in several ways, especially the fact that male and female adults must stay paired together throughout their lives for reproduction to be successful.

21 Jul 2023

Crystal engineering strategy could make medicines more soluble and palatable for children

Research conducted at University of Limerick in Ireland has shown that crystal engineering can improve access to a drug used in the treatment of a tropical disease affecting millions worldwide.

3 Apr 2023

Oil-based gels could make it easier for children to swallow medicines

For most children and even some adults, swallowing pills or tablets is difficult. To make it easier to give those medicines, researchers at MIT and Brigham and Women's Hospital have created a drug-delivering gel that is much easier to swallow and could be used to administer a variety of different kinds of drugs.

27 May 2022

Researchers develop oil-based gels as drug delivery systems for children in resource-limited countries

Administering medications to children poses unique challenges, especially in resource-limited countries with high infant and child mortality rates.

27 May 2022

Researchers identify how a critical schistosomiasis drug works on the molecular level

Independent teams from Texas Biomedical Research Institute and the Medical College of Wisconsin have published two papers in Science Translational Medicine identifying how the only approved drug to treat schistosomiasis, a widespread parasitic worm infection, works on the molecular level.

6 Jan 2022

Research may pave the way for designing new therapies to combat schistosomiasis

Neglected tropical diseases (NTDs) represent a group of about 20 conditions that affect more than a billion people worldwide.

6 Jan 2022

Two studies shed light on the biology and potential vulnerabilities of schistosomes

Two studies led by UT Southwestern researchers shed light on the biology and potential vulnerabilities of schistosomes - parasitic flatworms that cause the little-known tropical disease schistosomiasis.

24 Sep 2020

Bayer supports WHO through donated medicines for treatment of T. solium infection

A recent agreement between the World Health Organization and the German pharmaceutical company Bayer promises hope of expanding access to essential medicines for the treatment of people exposed to or infected by the pork tapeworm Taenia solium.

12 Aug 2020

Study uncovers how schistosome worms trick the host's immune system

Researchers uncovered in a new study how schistosomes, parasitic flatworms that infect more than 200 million people in the tropics, trick the host's immune system and continue producing eggs for decades.

3 Aug 2020

Research could open a promising new path to control schistosomiasis

Scientists have isolated a natural chemical that acts as a potent kryptonite against parasitic worms that burrow through human skin and cause devastating health problems.

From PLOS ONE 18 Oct 2019

Research could lead to new ways to fight against schistosomiasis

Scientists at the Morgridge Institute for Research have isolated a natural chemical that acts as a potent kryptonite against schistosomes, the parasitic worms that burrow through human skin and cause devastating health problems.

17 Oct 2019

Schistosomiasis prevention and treatment could help control HIV

Of the 34 million people worldwide with HIV, and the 200 million with schistosomiasis, the majority live in Africa— where millions of people are simultaneously infected with both diseases.

13 Dec 2018

Study: Young children should be priority for snail fever treatment

Infants in some of the world's poorest regions are vulnerable to a common worm parasite infection and their treatment should become a priority, according to a study.

17 Apr 2018

UNM professor receives $1.9-million NIH grant to battle against pervasive African parasite

UNM Distinguished Professor of Biology Eric S. Loker began studying the parasite that causes this disease more than three decades ago and is widely considered one of the world's foremost experts in this field. Loker was recently awarded a five-year, $1.9-million grant from the National Institutes of Health to continue his work in Africa.

2 Aug 2017

Schistosomiasis: the biggest killer you’ve never heard of?

Schistosomiasis is a parasitic disease, sometimes called bilharzia or snail fever. The disease impacts a huge number of people around the world, over 230 million people are infected with one of the schistosome species, the parasitic worms that causes the disease.

4 Jul 2017

The Global Schistosomiasis Alliance unveils giant worm on Lake Geneva

Experts gather at Neglected Tropical Diseases Summit to demand more global action to tackle one of the world’s biggest killers - schistosomiasis.

18 Apr 2017

GHIT Fund invests in phase 3 clinical trial for pediatric formulation of ‘snail fever’ drug

The Global Health Innovative Technology Fund, a unique Japanese public-private partnership formed to battle infectious diseases around the globe, today announced 11 new investments totaling US$23 million that could help deliver a range of new innovative therapies for a host of debilitating conditions.

31 Mar 2017

Naturally occurring protein shows promise as biocontrol weapon against schistosomiasis

A naturally occurring protein has been discovered that shows promise as a biocontrol weapon against schistosomiasis, one of the world's most prevalent parasitic diseases, Oregon State University researchers reported today in a new study.

15 Feb 2017