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From Cells to Drugs: How Cell Painting is Transforming Drug Discovery

In this interview, Jordi Carreras delves into the fascinating world of Cell Painting, a powerful technology gaining momentum in drug discovery. He shares insights into his groundbreaking research, the unique aspects of Phenaros' drug discovery platform, and the synergy between academia and industry.

From ELRIG (UK) Ltd. 1 Nov 2023

Researchers develop new method for mapping how the parts of the brain "speak" to each other

A research team led by Cleveland Clinic and Oregon Health and Science University (OHSU) has developed a new method for mapping how the parts of the brain "speak" to each other, critical to understanding behavior changes in patients with neurological disease.

31 Oct 2023

Next-generation vaccine candidates protect against multiple strains of influenza and last longer

Recent preclinical results indicate novel next-generation vaccine candidates developed at Cleveland Clinic protect against multiple strains of influenza and last longer than vaccines currently in use.

31 Oct 2023

AI may help identify potential gonorrhea vaccine proteins

Gonorrhea, a sexually transmitted bacterial infection that affects more than 80 million people worldwide every year, has become resistant to almost all known antibiotics.

31 Oct 2023

Using synthetic biology to develop smarter cell therapies for cancer patients

We are embarking on an unprecedented era of therapeutic development enabled by live cell engineering.

31 Oct 2023

UQ's drug discovery facility opens to researchers nationwide after $1.9M funding injection

The University of Queensland's small molecule drug discovery facility will open its doors to researchers from across Australia for the first time thanks to a National Collaborative Research Infrastructure Strategy (NCRIS) funding injection.

30 Oct 2023

Redefining the battle against Alzheimer's with tau-focused treatments

Researchers explore the potential of tau-targeting therapies in treating Alzheimer's disease, focusing on immunotherapies and strategies to improve their efficacy. The study dives into the complex biology of tau proteins, their modifications, and how they can be targeted to halt the progression of Alzheimer's.

29 Oct 2023

Reducing air pollution associated with lower risk of all-cause dementia and Alzheimer's disease

Previous reports have linked long-term air pollution exposure with accumulation of Alzheimer's disease-related brain plaques, but this is the first accumulated evidence that reducing pollution, especially fine particulates in the air and pollutants from the burning of fuel, is associated with lower risk of all-cause dementia and Alzheimer's disease.

27 Oct 2023

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

26 Oct 2023

$3.4 million grant awarded to identify therapeutic treatments for acute respiratory distress syndrome

A four-year, $3.4 million grant to investigate molecular mechanisms and therapeutic treatments for acute respiratory distress syndrome (ARDS) has been awarded to UTHealth Houston researchers by the National Heart, Lung, and Blood Institute, part of the National Institutes of Health.

26 Oct 2023

Doubts abound about a new Alzheimer’s blood test

For the first time, people worried about their risk of Alzheimer's disease can go online, order a blood test, and receive results in the privacy of their homes.

26 Oct 2023

How strep bacteria outsmart your immune system and why it matters for treatment

Researchers discover that Group A streptococcal infections alter immunoglobulin G (IgG) homeostasis to evade the immune system, affecting the transition from local to systemic infections. The study also raises concerns about the effectiveness of antibody-based therapies, as the bacteria's virulence factors can degrade therapeutic antibodies.

25 Oct 2023

Oxford Vaccine Group launches a pioneering study into human immunity

This study will test the responses of cells in lymph nodes before and after immunization with flu and COVID-19 vaccines and compare reactions in older and younger adults.

25 Oct 2023

New consortium to build on breakthroughs in malaria research to develop P. vivax vaccines

Plasmodium vivax is the most widespread human malaria-causing pathogen with 2.5 billion people living at risk in Africa, South America, Oceania, and Asia.

24 Oct 2023

Finding and targeting dormant tumor cells to prevent breast cancer recurrence

While breast cancer survival continues to improve, thanks to advances in detection and treatment, when breast cancer recurs – or returns after initial treatment – it is incurable.

24 Oct 2023

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

24 Oct 2023

New "pseudo cell" formulation could revolutionize treatment of vitreoretinal diseases

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and Beijing Chaoyang Hospital have developed a new "pseudo cell" formulation based on self-healing microcapsule-loading exosomes to treat diverse vitreoretinal diseases.

24 Oct 2023

Can strawberries mitigate Alzheimer's risk? Recent study suggests a possibility

Whether strawberry supplementation mitigates the risk for late-life dementia.

23 Oct 2023

Scientists develop gene therapy approach for rare paralyzing disease

The 50 families stretch from the Netherlands and the United Kingdom to the United States and China. Each family has a child who is paralyzed from a mutation in a single gene named Contactin-Associated Protein 1 (Cntnap1).

20 Oct 2023

Atovaquone "chemical vaccine" for malaria could be more feasible than thought

Johns Hopkins researchers looking to develop a long-acting, injectable malaria preventive using atovaquone have shown in a new study that resistance may not be the challenge scientists thought it was, particularly when using atovaquone as a malaria preventive.

20 Oct 2023

Preclinical News and Research

From Cells to Drugs: How Cell Painting is Transforming Drug Discovery

Researchers develop new method for mapping how the parts of the brain "speak" to each other

Next-generation vaccine candidates protect against multiple strains of influenza and last longer

AI may help identify potential gonorrhea vaccine proteins

Using synthetic biology to develop smarter cell therapies for cancer patients

UQ's drug discovery facility opens to researchers nationwide after $1.9M funding injection

Redefining the battle against Alzheimer's with tau-focused treatments

Reducing air pollution associated with lower risk of all-cause dementia and Alzheimer's disease

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

$3.4 million grant awarded to identify therapeutic treatments for acute respiratory distress syndrome

Doubts abound about a new Alzheimer’s blood test

How strep bacteria outsmart your immune system and why it matters for treatment

Oxford Vaccine Group launches a pioneering study into human immunity

New consortium to build on breakthroughs in malaria research to develop P. vivax vaccines

Finding and targeting dormant tumor cells to prevent breast cancer recurrence

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

New "pseudo cell" formulation could revolutionize treatment of vitreoretinal diseases

Can strawberries mitigate Alzheimer's risk? Recent study suggests a possibility

Scientists develop gene therapy approach for rare paralyzing disease

Atovaquone "chemical vaccine" for malaria could be more feasible than thought

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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