Progenitor Cells News and Research

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Researchers engineer adult stem cells derived from human umbilical cord blood to produce insulin

The researchers announced their laboratory finding, which caps nearly four years of research, in the June 2007 issue of the medical journal Cell Proliferation, posted online this week.

28 May 2007

New adult nerves have a deeper role than simply replacing dead ones

You may not be able to relive your youth, but part of your brain can. Johns Hopkins researchers have found that newly made nerves in an adult brain's learning center experience a one-month period when they are just as active as the nerves in a developing child.

24 May 2007

Brca2 gene prevents medulloblastoma

Investigators at St. Jude Children's Research Hospital have gained some of the first major insights into how certain genes known to prevent cancer also guide the normal development of the nervous system before birth and during infancy by repairing DNA damage.

22 May 2007

Researchers identify antioxidant mechanisms involved in protection against heart disease

Zvonimir Katusic, M.D., Ph.D., and Mayo colleagues have identified antioxidant mechanisms essential for regenerative function of endothelial progenitor cells (EPCs).

30 Apr 2007

Small amounts of stem/progenitor cells from bone marrow enhance repair of damaged tissues

New studies in the laboratory of Dr. Darwin J. Prockop, Director of Tulane University's Center for Gene Therapy, are shedding light on the previously mysterious mechanism through which even relatively small amounts of stem/progenitor cells taken from a patient's own bone marrow enhance repair of damaged tissues.

30 Apr 2007

Scientists develop method to convert normal human blood cells into

Cancer researchers led by Dr. John Dick at Ontario Cancer Institute (OCI) have developed a method to convert normal human blood cells into "human" leukemia stem cells.

27 Apr 2007

Scientists tackle cancer with different approaches

Studies presented at the 2007 meeting of the American Association for Cancer Research show how researchers are using the new, as well as the natural, to help design and test new drugs to treat cancer.

18 Apr 2007

Study suggests reason for high incidence of cancer in the prostate

Cancer occurs more frequently in the prostates of men than in any organ other than the skin. While DNA damage caused by exposure to the sun is likely the cause of many skin cancers, the cause of prostate cancer remains largely unknown.

12 Apr 2007

Stem cell therapy shows promise for degenerative diseases of the eye

For the millions of Americans whose vision is slowly ebbing due to degenerative diseases of the eye, the lowly neural progenitor cell may be riding to the rescue.

3 Apr 2007

Atorvastatin shows potential as a new treatment for spinal cord injuries

A multidisciplinary investigation led by Inderjit Singh, Ph.D, of the Medical University of South Carolina, has resulted in a new treatment of spinal cord injuries (SCI). The study investigates the efficacy of atorvastatin (AT), (i.e. Lipitor) as a treatment for spinal cord injuries following trauma.

22 Mar 2007

Researchers show how endocrine cell types are produced in the pancreas

An international research team has identified the process by which pancreatic progenitor cells give rise to different endocrine cell types.

8 Mar 2007

New discovery suggests novel methods for treating acute lymphoblastic leukemia

Investigators at St. Jude Children's Research Hospital have discovered previously unsuspected mutations that contribute to the formation of pediatric acute lymphoblastic leukemia (ALL), the most common cancer in children.

8 Mar 2007

Perfluorocarbon nanoparticles track living cells

Stem cell therapy, primarily bone marrow transplantation, plays a key role in treating leukemia and other types of cancer.

26 Feb 2007

Rate of stem cell transplants among African-Americans lower

Lower transplant rates in ethnic communities may be explained somewhat by a lack of suitable anonymous donors, a problem the medical community has long known and been working to address. Surprisingly, the study found the discrepancy in treatment held true even when the transplant was autologous (e.g. self-donated stem cells were used) or when the cells were donated by a relative, typically a sibling.

11 Feb 2007

Scientists discover master switches for adult blood stem cells

Johns Hopkins Kimmel Cancer Center scientists have found a set of "master switches" that keep adult blood-forming stem cells in their primitive state.

8 Feb 2007

FDA issues guidance on license applications for placental/umbilical cord blood products

The Food and Drug Administration (FDA) has issued a draft guidance recommending a streamlined path to licensure for establishments that manufacture cord blood for certain medical conditions.

16 Jan 2007

Retinoblastoma gene may play a critical role in the development of the placenta

An important cancer-related gene may play a critical role in the development of the placenta, the organ that controls nutrient and oxygen exchange between a mother and her fetus during pregnancy, and perhaps in miscarriages.

10 Jan 2007

A Trojan horse for gliomas

Gliomas are a group of brain tumors where the most common type is also the most aggressive one.

9 Jan 2007

Retinoblastoma gene may play a critical role in the development of the placenta

9 Jan 2007

New treatment for lower back pain using patient's own stem cells

A University of Manchester researcher has developed a treatment for lower back pain using the patient's own stem cells, which could replace the use of strong painkillers or surgery that can cause debilitation, neither of which addresses the underlying cause.

From The University of Manchester 2 Dec 2006