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Study reveals surprising findings on gene involved in human pregnancy

From an evolutionary perspective, human pregnancy is quite strange, says University at Buffalo biologist Vincent Lynch.

22 Apr 2020

Inflammation caused by radiation can promote survival of triple-negative breast cancer cells

While radiation is successfully used to treat breast cancer by killing cancer cells, inflammation caused as a side-effect of radiation can have a contrary effect by promoting the survival of triple-negative breast cancer cells, according to research published online in the International Journal of Radiation Biology by Jennifer Sims-Mourtada, Ph.D., director of Translational Breast Cancer Research at ChristianaCare's Helen F. Graham Cancer Center & Research Institute.

24 Feb 2020

FETO therapy produces favorable outcomes when fetal and maternal care are highly coordinated

Researchers from The Johns Hopkins Center for Fetal Therapy report new evidence that fetuses with severe congenital diaphragmatic hernia, a rare but life-threatening, lung-damaging condition, experience a significantly high rate of success for the fetal treatment known as FETO, if they and their mothers receive coordinated and highly experienced care in the same expert setting.

20 Feb 2020

New quick and convenient microfluidic chip to assess male fertility

Current tests for male fertility include measuring the concentration and motility of spermatozoa. However, other characteristics of sperm, such as their ability to follow a chemical trail to the egg, can influence the likelihood of fertilization.

19 Feb 2020

UGA historian shines light on the evolutionary purpose of menopause

Menopause- that time in every woman's life when the ovaries no longer release an egg each month and menstruation ceases forever- is a rare thing among Earth's infinitely varied creatures.

18 Feb 2020

Acid reflux drug may be a promising therapy to reduce preterm birth

Lansoprazole, an over-the-counter acid reflux drug that is often taken by pregnant women, may be a promising therapy to reduce preterm birth, according to a computational drug repurposing study that also tested several of the drugs in mice.

13 Feb 2020

Study suggests potential therapy option for early-stage breast cancer

Radionuclide therapy has proven successful in delaying the growth of disseminated tumor cells (DTCs) in early-stage breast cancer in a small animal model, suggesting its use as a potential adjuvant therapy for retarding the proliferation of DTCs.

5 Feb 2020

Experts think progesterone could prevent 8,500 miscarriages a year

According to two new studies from the University of Birmingham and Tommy's National Centre for Miscarriage Research, women who have bleeding during early pregnancy and who have had earlier miscarriages could benefit from a course of progesterone, with about 8,500 babies being saved each year.

2 Feb 2020

Call for FDA to withdraw preterm birth drug divides doctors and insurers

Doctors fear that the only drug approved to prevent preterm birth, the nation’s leading cause of infant mortality and disability, will no longer be available to expectant mothers.

27 Jan 2020

Three big AI projects in medicine to watch in 2020

Artificial intelligence (AI) is beginning to touch medicine in many different ways, from making diagnoses to triaging patients. Many AI enterprises will make headlines in 2020:

24 Jan 2020

Elagolix drug suppresses ovarian hormone production, prevents heavy menstrual bleeding

About 50 % of women with uterine fibroids--non-cancerous muscle tumors that grow in the uterus--experience heavy menstrual bleeding and other symptoms. Surgery is commonly recommended when these symptoms are severe enough to prompt a woman to seek treatment.

23 Jan 2020

Updated breast cancer guideline offers recommendations for handling cases with low ER expression

The updated guideline for estrogen and progesterone receptor (ER/PgR) testing in breast cancer, published jointly today by the College of American Pathologists and the American Society of Clinical Oncology, reaffirms much of the original guidance and has more specific recommendations for handling and reporting cases with low ER expression.

13 Jan 2020

Study hints a link between disruptions to progesterone signaling and recurrent miscarriage

About twenty percent of confirmed pregnancies end in miscarriage, most often in the first trimester, for reasons ranging from infection to chromosomal abnormality.

6 Jan 2020

Scientists successfully cultivate and characterize corpus luteum cells of cats

The reproduction of lynxes is highly mysterious. Unlike other wild cats, most lynxes are only receptive for a few days once a year.

20 Dec 2019

The evidence for BRCA1/2 or any genetic testing in breast cancer patients

A new statement by the American College of Medical Genetics and Genomics (ACMG), published in the journal Genetics in Medicine, discusses the place of germline genetic testing in breast cancer patients.

15 Dec 2019

Points to consider: Should germline genetic testing be offered to all patients with breast cancer?

Should germline genetic testing be offered to all patients with breast cancer? The American College of Medical Genetics and Genomics addresses this important question in a new statement published in Genetics in Medicine, "Points to Consider: Is There Evidence to Support BRCA1/2 and Other Inherited Breast Cancer Genetic Testing for All Breast Cancer Patients? A Statement of the American College of Medical Genetics and Genomics."

13 Dec 2019

ACMG recommends evaluations of breast cancer patients before genetic testing

According to a statement on behalf of the American College of Medical Genetics and Genomics (ACMG) published Dec. 13 in the organization's official journal, Genetics in Medicine, there is insufficient evidence to recommend universal genetic testing for BRCA1/2 alone or in combination with multi-gene panels for all breast cancer patients.

13 Dec 2019

New drug combo promises help for triple negative breast cancer patients

A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when used along with standard drugs than alone. The study, reported in the journal PLOS ONE, opens up a new door of opportunity for patients with this disease.

11 Dec 2019

Combination regimen shows promising results in preclinical models of triple negative breast cancer

Tumor volume in a preclinical model of triple negative breast cancer (TNBC) was reduced four times more when an experimental polo-like kinase 1 (PLK1) inhibitor was combined with a standard-of-care chemotherapeutic agent than when the agent was used alone.

10 Dec 2019

Trial investigating "abortion pill reversal" stops due to safety concerns

Scientists are calling for pro-life US states to abolish an unproven medication that supposedly "reverses" medical abortion.

9 Dec 2019