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CityU researchers identify super-enhancers that stimulate the activity of breast cancer genes

Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option, but the clinical result is unsatisfactory.

15 Apr 2021

Pregnancy increases the risk of first-time symptomatic kidney stone

Though researchers have long known that several physiological and anatomical changes occur during pregnancy that can contribute to kidney stone formation, evidence of the link has been lacking. But now Mayo Clinic researchers believe they have that evidence.

15 Apr 2021

Ovarian follicular function unaffected by SARS-CoV-2 infection or Pfizer vaccine, study finds

A new study by researchers in Jerusalem indicates that while specific antibodies to the virus are present in both serum and ovarian follicles following infection or vaccination, there is no apparent adverse effect on follicular function as a result.

15 Apr 2021

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Researchers at the University of California, San Francisco, have discovered that aggressive, triple-negative breast cancers (TNBCs) can evade treatment by reorganizing and softening the collagen matrix that surrounds the cancer cells.

3 Apr 2021

Exposure to endocrine-disrupting chemicals may increase likelihood of postpartum depression

Endocrine-disrupting chemicals may influence hormonal shifts during pregnancy as well as contribute to postpartum depression, according to a small study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

1 Apr 2021

Taking progestogens during high-risk pregnancy could reduce preterm birth

Taking progestogens - steroid hormones - during pregnancy could reduce the risk of preterm birth in high-risk single baby pregnancies, research has shown.

31 Mar 2021

Stem cell depletion could be an important factor behind miscarriage

Depletion of a certain type of stem cell in the womb lining during pregnancy could be a significant factor behind miscarriage, according to a study released today in STEM CELLS.

27 Mar 2021

YAP inhibitors could facilitate targeted treatment of basal-like breast cancer

Targeted treatment of basal-like breast cancer could be facilitated by YAP inhibitors in the future. As reported by an MDC team headed by Walter Birchmeier in the scientific journal Cancer Research, this type of cancer requires the support of the YAP protein to stimulate the growth of cancer stem cells.

22 Mar 2021

Male fertility and androgen production may be impacted by COVID-19

An interesting new study has appeared online in the journal Hormones that discusses the effects of COVID-19 on the male and female gonads.

22 Mar 2021

Progesterone therapy may improve clinical outcomes for male COVID-19 patients

COVID-19 disproportionately affects men compared with women, raising the possibility that a hormone like progesterone may improve clinical outcomes for certain hospitalized men with the disease.

18 Mar 2021

Study evaluates effectiveness of hormone therapies in managing postmenopausal nocturia

As women age, they are more likely to wake up in the middle of the night to pass urine. The loss of estrogen during the menopause transition accelerates this problem, which is known as nocturia.

17 Mar 2021

High levels of progesterone can reduce stress after concussion, speed recovery in females

Could birth control pills help young female athletes recover faster from concussions and reduce their symptoms?

16 Mar 2021

Unbalanced progesterone may cause preterm or prolonged labor in some pregnant women

New research by the National Institutes of Health found that unbalanced progesterone signals may cause some pregnant women to experience preterm labor or prolonged labor.

11 Mar 2021

Study uncovers mechanism to help explain how maternal stress causes idiopathic preterm birth

Preterm birth is a leading cause of infant deaths and illness in the U.S. -- yet its underlying molecular causes remain largely unclear. About 40 to 50% of preterm births, defined as births before 37 weeks of pregnancy, are estimated to be "idiopathic," meaning they arise from unexplained or spontaneous labor.

9 Mar 2021

Using decision theory for precise choice of breast cancer treatment

The precise choice of treatment for breast cancer depends upon the status of the hormone receptors (for oestrogen and progesterone). Their conventional determination by means of immunohistochemistry (IHC) is associated with a certain error rate, which can be reduced by adding genomic data.

8 Mar 2021

Progesterone News and Research

CityU researchers identify super-enhancers that stimulate the activity of breast cancer genes

Pregnancy increases the risk of first-time symptomatic kidney stone

Ovarian follicular function unaffected by SARS-CoV-2 infection or Pfizer vaccine, study finds

Treatment resistance in triple-negative breast cancers linked to softer tissue environment

Exposure to endocrine-disrupting chemicals may increase likelihood of postpartum depression

Taking progestogens during high-risk pregnancy could reduce preterm birth

Stem cell depletion could be an important factor behind miscarriage

YAP inhibitors could facilitate targeted treatment of basal-like breast cancer

Male fertility and androgen production may be impacted by COVID-19

Progesterone therapy may improve clinical outcomes for male COVID-19 patients

Study evaluates effectiveness of hormone therapies in managing postmenopausal nocturia

High levels of progesterone can reduce stress after concussion, speed recovery in females

Unbalanced progesterone may cause preterm or prolonged labor in some pregnant women

Study uncovers mechanism to help explain how maternal stress causes idiopathic preterm birth

Using decision theory for precise choice of breast cancer treatment

Study illuminates the role of HAND2 gene in timing of human labor

Study uses computational framework to identify tamoxifen resistance markers in ER+ breast cancer

Researchers develop a tiny, yet effective method for preventing premature birth

Understanding traumatic brain injury in women

Surgery may increase length of survival for metastatic breast cancer patients

Snapping at new biotech breakthroughs with Gator Pro

Realizing the Importance of Medical Electronic Devices

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